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The map label for this gene is ychE

Identifier: 157160747

GI number: 157160747

Start: 1346854

End: 1347501

Strand: Direct

Name: ychE

Synonym: EcHS_A1351

Alternate gene names: 157160747

Gene position: 1346854-1347501 (Clockwise)

Preceding gene: 157160745

Following gene: 157160748

Centisome position: 29.0

GC content: 48.3

Gene sequence:

>648_bases
GTGATTCAGACCTTTTTTGATTTTCCCGTTTACTTCAAATTTTTCATCGGGTTATTTGCGCTGGTCAACCCGGTAGGGAT
TATTCCCGTCTTTATCAGCATGACCAGTTATCAGACAGCGGCAGCGCGAAACAAAACTAACCTTACAGCCAACCTGTCTG
TGGCCATTATCTTGTGGATCTCGCTTTTTCTCGGCGACACGATTCTGCAACTTTTTGGTATATCAATTGATTCGTTCCGT
ATCGCCGGGGGCATCCTGGTGGTGACGATAGCGATGTCGATGATCAGCGGCAAGCTTGGCGAGGATAAACAGAACAAGCA
AGAAAAATCAGAAACCGCGGTACGTGAAAGCATTGGTGTGGTGCCATTGGCGTTGCCGTTGATGGCGGGGCCAGGGGCGA
TCAGTTCTACCATCGTCTGGGGTACGCGTTATCACAGCATTAGCTATCTGTTTGGTTTCTTTGTGGCTATTGCATTGTTC
GCTTTATGTTGCTGGGGATTGTTCCGCATGGCACCGTGGCTGGTACGGGTTTTACGCCAGACCGGCATCAACGTGATTAC
GCGTATTATGGGGCTATTGCTGATGGCATTGGGGATTGAATTTATCGTTACTGGTATTAAGGGGATTTTCCCCGGCCTGC
TTAATTAA

Upstream 100 bases:

>100_bases
AGTTAGGAGGTGAAAAATGCTGTCAAAAGGCGTATTGTCAGCGCGTCTTTTCAACCTTATTTATGGCTAACATTATCCGG
CTTTTGCTTCGGAGCTAACC

Downstream 100 bases:

>100_bases
TTCCTTTCAAATGAAACGGAGCTGCCATGCTCCGTTTACTTCGTCATTATTTTTACTTTGTTCCCGCGCAGTTATCAAAA
GCAAAAGGAATAGGTAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARNKTNLTANLSVAIILWISLFLGDTILQLFGISIDSFR
IAGGILVVTIAMSMISGKLGEDKQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN

Sequences:

>Translated_215_residues
MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARNKTNLTANLSVAIILWISLFLGDTILQLFGISIDSFR
IAGGILVVTIAMSMISGKLGEDKQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN
>Mature_215_residues
MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARNKTNLTANLSVAIILWISLFLGDTILQLFGISIDSFR
IAGGILVVTIAMSMISGKLGEDKQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family

Homologues:

Organism=Escherichia coli, GI1787494, Length=215, Percent_Identity=100, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1787809, Length=194, Percent_Identity=30.9278350515464, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789842, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCHE_ECOLI (P25743)

Other databases:

- EMBL:   X59501
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   E64871
- RefSeq:   AP_001866.1
- RefSeq:   NP_415758.1
- ProteinModelPortal:   P25743
- STRING:   P25743
- EnsemblBacteria:   EBESCT00000002032
- EnsemblBacteria:   EBESCT00000017610
- GeneID:   945836
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1229
- KEGG:   eco:b1242
- EchoBASE:   EB1318
- EcoGene:   EG11342
- eggNOG:   COG2095
- GeneTree:   EBGT00050000010129
- HOGENOM:   HBG731519
- OMA:   INIGTRL
- ProtClustDB:   PRK11111
- BioCyc:   EcoCyc:EG11342-MONOMER
- Genevestigator:   P25743
- InterPro:   IPR002771
- TIGRFAMs:   TIGR00427

Pfam domain/function: PF01914 MarC

EC number: NA

Molecular weight: Translated: 23522; Mature: 23522

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x145e9620)-; HASH(0x1450bb34)-; HASH(0x13f1c808)-; HASH(0x145f9410)-; HASH(0x14379c38)-; HASH(0x13f1c7a8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARNKTNLTANLSVAIILWI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGEDKQNKQEKSETAVRESIGV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCH
VPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALFALCCWGLFRMAPWLVRVLRQ
HHHHHHHHCCCCCHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARNKTNLTANLSVAIILWI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGEDKQNKQEKSETAVRESIGV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCH
VPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALFALCCWGLFRMAPWLVRVLRQ
HHHHHHHHCCCCCHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2015910; 9097039; 9278503