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The map label for this gene is wrbA [H]

Identifier: 157160526

GI number: 157160526

Start: 1128130

End: 1128726

Strand: Reverse

Name: wrbA [H]

Synonym: EcHS_A1117

Alternate gene names: 157160526

Gene position: 1128726-1128130 (Counterclockwise)

Preceding gene: 157160530

Following gene: 157160525

Centisome position: 24.31

GC content: 53.43

Gene sequence:

>597_bases
ATGGCTAAAGTTCTGGTGCTTTATTATTCCATGTACGGACATATTGAAACGATGGCACGCGCAGTCGCTGAGGGTGCAAG
CAAAGTGGATGGCGCAGAAGTTGTCGTTAAGCGTGTACCGGAAACCATGCCGCCGCAATTATTTGAAAAAGCAGGCGGTA
AAACGCAAACTGCACCGGTTGCAACCCCGCAAGAACTGGCCGATTACGACGCCATTATTTTTGGTACACCTACCCGCTTT
GGCAACATGTCCGGTCAAATGCGTACCTTCCTCGACCAGACGGGCGGCCTGTGGGCTTCCGGCGCACTATACGGAAAACT
GGCGAGCGTCTTTAGTTCCACCGGTACTGGCGGCGGTCAGGAACAAACTATTACTTCAACCTGGACGACCCTTGCGCATC
ACGGCATGGTAATTGTCCCCATTGGCTACGCAGCGCAGGAATTATTTGACGTTTCACAGGTTCGCGGCGGTACGCCGTAC
GGCGCAACAACCATCGCAGGCGGTGACGGCTCACGCCAGCCAAGCCAGGAAGAACTGTCTATTGCTCGTTATCAAGGGGA
ATATGTCGCAGGTCTGGCAGTTAAACTTAACGGCTAA

Upstream 100 bases:

>100_bases
TAAGTGGTTGTGAAATTTGCACTCTGAAAAGGACGTCTTATCTTTAAATAAGTGGTAGCGAATCGCTACGGAATAGAGAT
AACACGAGGAGTGGTTAGAA

Downstream 100 bases:

>100_bases
TCTTCAACAGGAGGATACGCATGCCAACTCAAGAAGCGAAAGCTCATCACGTCGGTGAATGGGCATCTCTGCGCAATACG
TCGCCGGAAATAGCCGAGGC

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: Trp repressor-binding protein [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRF
GNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG

Sequences:

>Translated_198_residues
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRF
GNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>Mature_197_residues
AKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFG
NMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYG
ATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG

Specific function: Seems to enhance the formation and/or stability of noncovalent complexes between the trp repressor protein and operator-bearing DNA [H]

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=198, Percent_Identity=100, Blast_Score=401, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6320235, Length=190, Percent_Identity=46.8421052631579, Blast_Score=176, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6319849, Length=201, Percent_Identity=46.2686567164179, Blast_Score=173, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319526, Length=203, Percent_Identity=37.4384236453202, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 20846; Mature: 20715

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPV
CCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCC
ATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQ
CCHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHHCCCCCCCC
EQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELS
CCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHH
IARYQGEYVAGLAVKLNG
HHHHCCCEEEEEEEEECC
>Mature Secondary Structure 
AKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPV
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCC
ATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQ
CCHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHHCCCCCCCC
EQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELS
CCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHH
IARYQGEYVAGLAVKLNG
HHHHCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA