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The map label for this gene is rutG [H]

Identifier: 157160530

GI number: 157160530

Start: 1130809

End: 1132137

Strand: Reverse

Name: rutG [H]

Synonym: EcHS_A1121

Alternate gene names: 157160530

Gene position: 1132137-1130809 (Counterclockwise)

Preceding gene: 157160531

Following gene: 157160526

Centisome position: 24.38

GC content: 53.88

Gene sequence:

>1329_bases
ATGGCAATGTTCGGTCTTCCTCACTGGCAGTTAAAATCGACCTCTACAGAGAGCGGCGTGGTCGCGCCGGATGAACGATT
GCCGTTTGCTCAGACGGCAATAATGGGCGTTCAACACGCGGTGGCGATGTTTGGCGCGACGGTGTTAATGCCGATTCTGA
TGGGGCTGGATCCCAATCTTTCCATTTTAATGTCGGGGATCGGCACATTACTGTTTTTCTTTATTACCGGCGGGCGCGTC
CCCAGTTATCTCGGTTCCAGCGCGGCTTTTGTCGGCGTGGTGATTGCCGCGACGGGCTTTAACGGTCAGGGCATTAACCC
GAATATCAGCATTGCGCTGGGCGGGATTATCGCCTGTGGGCTGGTTTATACCGTCATTGGCCTGGTGGTGATGAAAATCG
GTACACGCTGGATTGAACGGCTAATGCCGCCGGTGGTGACGGGTGCGGTGGTGATGGCGATTGGCCTGAACTTAGCGCCT
ATCGCAGTGAAAAGTGTATCGGCTTCGGCCTTTGATAGCTGGATGGCGGTAATGACGGTGCTGTGTATTGGGCTGGTGGC
GGTGTTTACCCGTGGCATGATCCAGCGATTATTGATTCTCGTAGGATTAATTGTCGCCTGTCTGCTGTATGGCGTGATGA
CCAACGTTTTAGGGCTGGGAAAAGCCGTCGATTTTACTCTCGTCAGCCATGCTGCCTGGTTCGGTTTGCCACATTTTTCC
ACTCCTGCTTTTAATGGTCAGGCAATGATGCTGATTGCGCCCGTGGCGGTGATTCTGGTGGCGGAAAACTTAGGCCATCT
CAAGGCGGTCGCCGGGATGACCGGACGCAATATGGATCCATATATGGGACGGGCATTCGTCGGTGATGGGCTGGCGACGA
TGCTTTCTGGTTCTGTCGGTGGCAGCGGCGTAACCACCTACGCCGAGAATATCGGTGTAATGGCCGTGACAAAAGTCTAC
TCGACGCTGGTGTTTGTCGCTGCTGCCGCCATCGCCATGCTGTTGGGCTTTTCACCGAAATTTGGCGCGCTGATTCATAC
CATTCCGGCCGCGGTGATTGGTGGTGCATCAATTGTTGTGTTCGGGCTGATTGCCGTCGCAGGCGCAAGGATCTGGGTAC
AAAACCGTGTCGATTTAAGCCAGAACGGTAATTTGATTATGGTCGCAGTAACCTTAGTGCTGGGCGCGGGTGATTTTGCT
CTCACGCTGGGCGGTTTTACGTTGGGAGGGATTGGTACAGCAACCTTTGGCGCGATTTTACTCAATGCGTTGTTAAGCAG
AAAGTTGGTTGACGTTCCACCGCCAGAAGTTGTTCATCAGGAGCCATAA

Upstream 100 bases:

>100_bases
CGATTCATCGTCACGCCACACCCTACGGGCTGGTGTGGTTCGATCGCAGTTATCACGCGCTGATGCGCCCTGCTTGTTAA
CCTCCTTAAGGAGACAGCTG

Downstream 100 bases:

>100_bases
ACAGAAAACCGCCGGGATTACCCGGCGGTGCAGATTGTTGACAACGTACGCATTGTTCATGCCGGATGCGGCGTAAACGC
CTTATCCGGCCTACAAAACA

Product: putative purine permease ycdG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MAMFGLPHWQLKSTSTESGVVAPDERLPFAQTAIMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRV
PSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAAAIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFA
LTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP

Sequences:

>Translated_442_residues
MAMFGLPHWQLKSTSTESGVVAPDERLPFAQTAIMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRV
PSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAAAIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFA
LTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP
>Mature_441_residues
AMFGLPHWQLKSTSTESGVVAPDERLPFAQTAIMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVP
SYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPI
AVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFST
PAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYS
TLVFVAAAAIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFAL
TLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=442, Percent_Identity=99.3212669683258, Blast_Score=859, Evalue=0.0,
Organism=Escherichia coli, GI1788843, Length=425, Percent_Identity=36.9411764705882, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI87082181, Length=457, Percent_Identity=26.0393873085339, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI87082178, Length=407, Percent_Identity=26.5356265356265, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=174, Percent_Identity=34.4827586206897, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17542260, Length=174, Percent_Identity=34.4827586206897, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17542262, Length=176, Percent_Identity=30.1136363636364, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17558856, Length=181, Percent_Identity=29.2817679558011, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17541904, Length=175, Percent_Identity=29.1428571428571, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356175, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45510; Mature: 45379

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AMFGLPHWQLKSTSTESGVVAPDERLPFAQTAIMGVQHAVAMFGATVLMPILMGLDPNL
CCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACG
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHEEEECCCCCCCCCCCEEHHHHHHHHH
LVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVG
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHCHHHHCCCHHHHHCCCCC
GSGVTTYAENIGVMAVTKVYSTLVFVAAAAIAMLLGFSPKFGALIHTIPAAVIGGASIVV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHH
FGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAIL
HHHHHHHHHHEEEECCCCCCCCCCEEEEEHHHHHCCCCCEEEECCEEECCHHHHHHHHHH
LNALLSRKLVDVPPPEVVHQEP
HHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]