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The map label for this gene is sulA

Identifier: 157160479

GI number: 157160479

Start: 1082024

End: 1082533

Strand: Reverse

Name: sulA

Synonym: EcHS_A1067

Alternate gene names: 157160479

Gene position: 1082533-1082024 (Counterclockwise)

Preceding gene: 157160481

Following gene: 157160478

Centisome position: 23.31

GC content: 48.24

Gene sequence:

>510_bases
ATGTACACTTCAGGCTATGCACATCGTTCTTCGTCGTTCTCATCCGCAGCAAGTAAAATTGCGCGTGTCTCTACGGAAAA
CACTACAGCCGGGCTTATCAGTGAAGTTGTCTATCGCGAAGATCAGCCCATGATGACGCAACTTCTACTGTTGCCATTGT
TACAGCAACTCGGTCAGCAATCGCGCTGGCAACTCTGGTTAACACCGCAACAAAAACTGAGTCGGGAATGGGTTCAGGCA
TCTGGGCTACCCTTAACGAAAGTAATGCAGATTAGCCAGCTCTCCCCTTGCCACACTGTGGAGTCAATGGTTCGCGCTTT
ACGCACGGGCAATTACAGTGTGGTGATCGGTTGGTTGGCAGATGATTTGACTGAAGAAGAGCATGCTGAACTTGTTGATG
CGGCAAATGAAGGTAACGCTATGGGGTTTATTATGCGTCCGGTAAGCGCATCCTCTCACGCCACGAGACAACTTTCCGGG
CTAAAAATTCACTCTAATTTGTATCATTAA

Upstream 100 bases:

>100_bases
CGACAAAATTTGCGAGGCTCTTTCCGAAAATAGGGTTGATCTTTGTTGTCACTGGATGTACTGTACATCCATACAGTAAC
TCACAGGGGCTGGATTGATT

Downstream 100 bases:

>100_bases
GTAAATTTAGGATTAATCCTGGAACTTTTTTTGTCGCCCAGCCAATGCTTTCAGTCGTGACTAATTTTCCTTGCGGAGGC
TTGTCTGAAGCGGTTTCCGC

Product: SOS cell division inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQA
SGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
LKIHSNLYH

Sequences:

>Translated_169_residues
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQA
SGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
LKIHSNLYH
>Mature_169_residues
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQA
SGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
LKIHSNLYH

Specific function: Component of the SOS system and an inhibitor of cell division. Accumulation of sulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of ftsZ in a 1:1 r

COG id: COG5404

COG function: function code D; SOS-response cell division inhibitor, blocks FtsZ ring formation

Gene ontology:

Cell location: Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulA family

Homologues:

Organism=Escherichia coli, GI1787192, Length=169, Percent_Identity=100, Blast_Score=348, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SULA_ECO24 (A7ZK62)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001462191.1
- ProteinModelPortal:   A7ZK62
- SMR:   A7ZK62
- STRING:   A7ZK62
- EnsemblBacteria:   EBESCT00000019760
- GeneID:   5586838
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_1072
- eggNOG:   COG5404
- GeneTree:   EBGT00050000011847
- HOGENOM:   HBG416377
- OMA:   EWVQSAG
- ProtClustDB:   PRK10595
- BioCyc:   ECOL331111:ECE24377A_1072-MONOMER
- HAMAP:   MF_01179
- InterPro:   IPR004596
- PIRSF:   PIRSF003093
- TIGRFAMs:   TIGR00623

Pfam domain/function: PF03846 SulA

EC number: NA

Molecular weight: Translated: 18802; Mature: 18802

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQ
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
SRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLA
CCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHH
DDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
HHCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCEECCCCCCC
>Mature Secondary Structure
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQ
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
SRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLA
CCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHH
DDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
HHCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA