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The map label for this gene is ompA [H]

Identifier: 157160478

GI number: 157160478

Start: 1080627

End: 1081667

Strand: Reverse

Name: ompA [H]

Synonym: EcHS_A1066

Alternate gene names: 157160478

Gene position: 1081667-1080627 (Counterclockwise)

Preceding gene: 157160479

Following gene: 157160476

Centisome position: 23.29

GC content: 53.6

Gene sequence:

>1041_bases
ATGAAAAAGACAGCTATCGCGATTGCAGTGGCACTGGCTGGTTTCGCTACCGTAGCGCAGGCCGCTCCGAAAGATAACAC
CTGGTACACTGGTGCTAAACTGGGCTGGTCCCAGTACCATGACACTGGTTTCATCAACAACAATGGCCCGACCCATGAAA
ACCAACTGGGCGCTGGTGCTTTTGGTGGTTACCAGGTTAACCCGTATGTTGGCTTTGAAATGGGTTACGACTGGTTAGGT
CGTATGCCGTACAAAGGCAGCGTTGAAAACGGTGCATACAAAGCTCAGGGCGTTCAACTGACCGCTAAACTGGGTTACCC
AATCACTGACGACCTAGACATCTACACTCGTCTGGGTGGTATGGTATGGCGTGCAGACACTAAATCCAACGTTTATGGTA
AAAACCACGACACCGGCGTTTCTCCGGTCTTCGCTGGCGGTGTTGAGTACGCGATCACTCCTGAAATCGCTACCCGTCTG
GAATACCAGTGGACCAACAACATCGGTGACGCACACACCATCGGCACTCGTCCGGACAACGGCATGCTGAGCCTGGGTGT
TTCCTACCGTTTCGGTCAGGGCGAAGCAGCTCCAGTAGTTGCTCCGGCTCCAGCTCCGGCACCGGAAGTACAGACCAAGC
ACTTCACTCTGAAGTCTGACGTTCTGTTCAACTTCAACAAAGCAACCCTGAAACCGGAAGGTCAGGCTGCTCTGGATCAG
CTGTACAGCCAGCTGAGCAACCTGGATCCGAAAGACGGTTCCGTAGTTGTTCTGGGTTACACCGACCGCATCGGTTCTGA
CGCTTACAACCAGGGTCTGTCCGAGCGCCGTGCTCAGTCTGTTGTTGATTACCTGATCTCCAAAGGTATCCCGGCAGACA
AGATCTCCGCACGTGGTATGGGCGAATCCAACCCGGTTACTGGCAACACCTGTGACAACGTGAAACAGCGTGCTGCACTG
ATCGACTGCCTGGCTCCGGATCGTCGCGTAGAGATCGAAGTTAAAGGTATCAAAGACGTTGTAACTCAGCCGCAGGCTTA
A

Upstream 100 bases:

>100_bases
GTAGAGTTAATATTGAGCAGATCCCCCGGTGAAGGATTTAACCGTGTTATCTCGTTGGAGATATTCATGGCGTATTTTGG
ATGATAACGAGGCGCAAAAA

Downstream 100 bases:

>100_bases
GTTCTCGTCTGGTAGAAAAACCCCGCTGCTGCGGGGTTTTTTTTGCCTTTAGTAAATTGAACTGACTTTCGTCAGTTATT
CCTTACCCAGCAATGCCTGC

Product: outer membrane protein A

Products: NA

Alternate protein names: Outer membrane protein II [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLG
RMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRL
EYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQ
LYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAAL
IDCLAPDRRVEIEVKGIKDVVTQPQA

Sequences:

>Translated_346_residues
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLG
RMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRL
EYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQ
LYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAAL
IDCLAPDRRVEIEVKGIKDVVTQPQA
>Mature_346_residues
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLG
RMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRL
EYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQ
LYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAAL
IDCLAPDRRVEIEVKGIKDVVTQPQA

Specific function: Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes [H

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787191, Length=346, Percent_Identity=100, Blast_Score=713, Evalue=0.0,
Organism=Escherichia coli, GI48994946, Length=120, Percent_Identity=35.8333333333333, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Mi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR002368
- InterPro:   IPR006690
- InterPro:   IPR000498
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA; PF01389 OmpA_membrane [H]

EC number: NA

Molecular weight: Translated: 37201; Mature: 37201

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS01068 OMPA_1 ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGA
CCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHCCCCEECCCCCCCCCCCCCCC
FGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGG
CCCEEECCEEEHCCCHHHHCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCHHHHHHHCC
MVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDN
EEEEECCCCCCCCCCCCCCCCCEEECCCCEEECHHHHHEEEEEECCCCCCCCCCCCCCCC
GMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQ
CEEEEEEEEEECCCCCCCEEECCCCCCCCCCCEEEEEECCEEEECCCCCCCCCCHHHHHH
LYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGM
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCC
GESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCC
>Mature Secondary Structure
MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGA
CCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHCCCCEECCCCCCCCCCCCCCC
FGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGG
CCCEEECCEEEHCCCHHHHCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCHHHHHHHCC
MVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDN
EEEEECCCCCCCCCCCCCCCCCEEECCCCEEECHHHHHEEEEEECCCCCCCCCCCCCCCC
GMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQ
CEEEEEEEEEECCCCCCCEEECCCCCCCCCCCEEEEEECCEEEECCCCCCCCCCHHHHHH
LYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGM
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCC
GESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1955870 [H]