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The map label for this gene is hutI

Identifier: 156980645

GI number: 156980645

Start: 2456281

End: 2457519

Strand: Reverse

Name: hutI

Synonym: SAHV_2314

Alternate gene names: 156980645

Gene position: 2457519-2456281 (Counterclockwise)

Preceding gene: 156980646

Following gene: 156980644

Centisome position: 85.33

GC content: 36.08

Gene sequence:

>1239_bases
ATGAATGATTTAATAATTAATCACATAGCAGAATTAATTTTACCGAAATCAACAGATAAACCTTTGAAGGGTAAGGAATT
AGATGAATTAAATGTTGTGAAAAATGGTACAGTTGTCATTAAAGATGGCAAAATTGTATATGCTGGACAACATACAGATG
ACTATGATGCGACTGAGACGATAGATGCTAGTGGAAAAGTAGTTTCTCCGGCATTAGTAGATGCTCATACCCATTTAACA
TTTGGTGGATCTCGAGAACATGAGATGTCATTAAAACGTCAAGGTAAGTCTTACCTTGAAATATTAGAAATGGGTGGTGG
CATATTATCTACCGTTAATGCTACTAGAGAAACATCCGAAGATGACTTGTTTAAAAAAGCAGAGCATGATTTGCTTACTA
TGATTAAACACGGCGTGCTTGCAGTTGAAAGTAAGAGTGGTTATGGATTAGATAGAGAAAATGAACTGAAGCAATTGAAA
GTGTCTAATCGTTTAGCTGAGAAATATGATTTAGACATGAAACATACTTTCCTAGGGCCTCATGCTGTACCTAAAGAGGC
AAGTTCAAATGAGGCATTTTTAGAAGAAATGATTGCGTTACTTCCGGAAGTAAAACAATATGCAGACTTTGCGGATATTT
TCTGTGAAACAGGTGTATTTACAATAGAACAATCGCAACATTATATGCAAAAAGCCAAAGAAGCAGGTTTTAAAGTGAAA
ATACATGCGGATGAAATTGATCCGTTAGGCGGACTGGAATTAGCAATTGATGAACAAGCAATATCAGCAGACCACTTAGT
AGCTTCTAGTGATAAAGGAAAAGAAAAGTTGCGAAATAGTGATACTGTAGCTGTCCTCTTACCTGCAACGACGTTCTATT
TAGGTAAAGAAGATTATGCAGATGCGAGAGGTATGCTTGATAATAATGGTGCCATCGCGTTAGCTACTGATTATAATCCA
GGCAGCAGTGTAACGAATAACTTGCAACTTGTTATGGCCATTGCAGCATTAAAATTAAAGCTTTCGCCTAGTGAAGTGTG
GAATGCTGTTACGGTCAACGCTGCTAAAGCAATAGATATTAACGCGGGTACAATTAACACAGGTGATAAGGCTAATTTAG
TAATTTGGGATGCACCAAATCATGAATATATTCCATATCATTTTGGTATCAATCACGCAGAAAAAGTTATTAAAGACGGT
AAGGTCATCGTAGATAACACATTATCTTTTAAAGCATAA

Upstream 100 bases:

>100_bases
GTGTTGCCCGACATGTTGATGCTGGCTATGACATCGCTATTCAAACAGCTAAAGAAAAAGGTATTCATATTCCAATGATT
GATAAAGCAGGTGATAAATA

Downstream 100 bases:

>100_bases
AATAATTAGAAAGCTCTAAGCATTGGTTTACACTAATGTTTAGAGCTTTTGTGGTTTGTAAAAACAAGTTTATCCGAGAA
CACGTTTTTGTATAGATTCT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MNDLIINHIAELILPKSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATETIDASGKVVSPALVDAHTHLT
FGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLK
VSNRLAEKYDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVK
IHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNP
GSSVTNNLQLVMAIAALKLKLSPSEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDG
KVIVDNTLSFKA

Sequences:

>Translated_412_residues
MNDLIINHIAELILPKSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATETIDASGKVVSPALVDAHTHLT
FGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLK
VSNRLAEKYDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVK
IHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNP
GSSVTNNLQLVMAIAALKLKLSPSEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDG
KVIVDNTLSFKA
>Mature_412_residues
MNDLIINHIAELILPKSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATETIDASGKVVSPALVDAHTHLT
FGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLK
VSNRLAEKYDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVK
IHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNP
GSSVTNNLQLVMAIAALKLKLSPSEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDG
KVIVDNTLSFKA

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=395, Percent_Identity=35.4430379746835, Blast_Score=226, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17555004, Length=411, Percent_Identity=34.0632603406326, Blast_Score=214, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_STAA1 (A7X5T3)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442904.1
- ProteinModelPortal:   A7X5T3
- SMR:   A7X5T3
- STRING:   A7X5T3
- EnsemblBacteria:   EBSTAT00000002739
- GeneID:   5559319
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2314
- eggNOG:   COG1228
- GeneTree:   EBGT00050000025449
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   SAUR418127:SAHV_2314-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 45025; Mature: 45025

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: BINDING 85-85 BINDING 98-98 BINDING 148-148 BINDING 181-181 BINDING 245-245

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLIINHIAELILPKSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATET
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEECCEEEEECCCCCCCCCCCE
IDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSE
ECCCCCEECCHHEECEEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCH
DDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLKVSNRLAEKYDLDMKHTFLGP
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
HAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCEEE
IHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYA
EECCCCCCCCCEEEEECHHHCCHHHEEECCCCCHHHHCCCCCEEEEEECEEEEECCCHHH
DARGMLDNNGAIALATDYNPGSSVTNNLQLVMAIAALKLKLSPSEVWNAVTVNAAKAIDI
HHCCEECCCCEEEEEECCCCCCCHHHHHHHHEEEHHHHEECCHHHHCCEEEECCEEEEEE
NAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDGKVIVDNTLSFKA
CCCEECCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MNDLIINHIAELILPKSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATET
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEECCEEEEECCCCCCCCCCCE
IDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSE
ECCCCCEECCHHEECEEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCH
DDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLKVSNRLAEKYDLDMKHTFLGP
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
HAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCEEE
IHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYA
EECCCCCCCCCEEEEECHHHCCHHHEEECCCCCHHHHCCCCCEEEEEECEEEEECCCHHH
DARGMLDNNGAIALATDYNPGSSVTNNLQLVMAIAALKLKLSPSEVWNAVTVNAAKAIDI
HHCCEECCCCEEEEEECCCCCCCHHHHHHHHEEEHHHHEECCHHHHCCEEEECCEEEEEE
NAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDGKVIVDNTLSFKA
CCCEECCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA