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The map label for this gene is gcp

Identifier: 156980365

GI number: 156980365

Start: 2172593

End: 2173618

Strand: Reverse

Name: gcp

Synonym: SAHV_2034

Alternate gene names: 156980365

Gene position: 2173618-2172593 (Counterclockwise)

Preceding gene: 156980366

Following gene: 156980362

Centisome position: 75.47

GC content: 37.62

Gene sequence:

>1026_bases
ATGACTAAAGATATATTAATACTAGCTGTTGAAACAAGTTGTGATGAAACAAGCGTTAGTGTTATAAAAAATGGCAGAGA
TATTTTATCAAATACAGTTTTAAGTCAGATTGAAAGTCATAAACGATTTGGCGGTGTCGTTCCCGAAGTGGCAAGTAGAC
ATCACGTTGAAGGTATAACAACAACAATAAACGAGGCTCTAGTGGATGCCGATGTATCAATGGAAGATATTGATGCCATA
GCGGTTACAGAAGGCCCTGGACTAATTGGTGCGTTACTAATAGGTGTTAATGCAGCCAAAGCATTGGCATTTGCTTACGA
TAAGCCACTTATTCCTGTTCATCATATTGCAGGACATATATATGCTAATCACATAGAAGAGCCATTAACATTCCCGCTAA
TTGCACTTATTGTTTCAGGTGGACATACTGAATTAGTTTATATGAAAGATCATTTATCATTTGAAGTCATTGGTGAAACA
CGAGATGACGCAGTAGGTGAGGCTTATGATAAAGTGGCACGAACAATTGGTTTAAATTATCCAGGTGGTCCACAAGTTGA
TCGGTTGGCTGCTGAAGGTGAAGATACTTATTCATTCCCTCGTGTTTGGTTGGATAAAGATAGTTATGATTTTAGTTTTA
GTGGGTTGAAAAGTGCCGTGATCAATCAACTTCACAATCAACGACAAAAAAATATTCCAATCATTGAAGCTAACGTAGCA
ACGAGCTTTCAAAATAGTGTTGTAGAGGTGCTTACGTTTAAAGCTATTCAAGCTTGTAAAGAATATAGTGTTCAGCGATT
AATTGTTGCTGGTGGCGTGGCGAGTAATAAAGGATTACGTCAATCTTTAGCGGATCAATGCAAAGTCAATGACATTCAAT
TAACTATCCCAAGTCCTAAATTATGCACAGATAATGCTGCAATGATAGGCGTTGCCGGCCACTCTTTGTATCAGCAAGGT
CGATTTGCTGATTTAGCATTAAATGGGCACAGCAATATAGATTTAGAAGAGTATTCTGCAGAATAA

Upstream 100 bases:

>100_bases
GCACAACATGTATATGAAAATTTAGGATTTCAATATGGTGGTAAACGTAAAAATTATTATGGTGAAGGTGAGGACGCAAT
GGTTATGTGGGTGAATTTAA

Downstream 100 bases:

>100_bases
AATAAACGTCAGTTATTAACATGATTACGATGAACATTATTGAAACTGTTCATAGTCTTCTGTCATGTGATAGCTGACGT
TTTTATATTGCAATTAGGGG

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITTTINEALVDADVSMEDIDAI
AVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGET
RDDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
TSFQNSVVEVLTFKAIQACKEYSVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHSLYQQG
RFADLALNGHSNIDLEEYSAE

Sequences:

>Translated_341_residues
MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITTTINEALVDADVSMEDIDAI
AVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGET
RDDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
TSFQNSVVEVLTFKAIQACKEYSVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHSLYQQG
RFADLALNGHSNIDLEEYSAE
>Mature_340_residues
TKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITTTINEALVDADVSMEDIDAIA
VTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGETR
DDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVAT
SFQNSVVEVLTFKAIQACKEYSVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHSLYQQGR
FADLALNGHSNIDLEEYSAE

Specific function: Critical mediator involved in the modification of cell wall peptidoglycan synthesis and/or cell division. Essential for cell viability

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=332, Percent_Identity=32.5301204819277, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI8923380, Length=326, Percent_Identity=30.0613496932515, Blast_Score=135, Evalue=5e-32,
Organism=Escherichia coli, GI1789445, Length=336, Percent_Identity=41.9642857142857, Blast_Score=288, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=30.1538461538462, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=334, Percent_Identity=29.940119760479, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320099, Length=356, Percent_Identity=30.6179775280899, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6322891, Length=294, Percent_Identity=27.5510204081633, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129063, Length=334, Percent_Identity=30.5389221556886, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI21357207, Length=330, Percent_Identity=27.8787878787879, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_STAA1 (A7X4L9)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442624.1
- ProteinModelPortal:   A7X4L9
- SMR:   A7X4L9
- STRING:   A7X4L9
- MEROPS:   M22.001
- EnsemblBacteria:   EBSTAT00000002946
- GeneID:   5560219
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2034
- eggNOG:   COG0533
- GeneTree:   EBGT00050000024961
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   SAUR418127:SAHV_2034-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36863; Mature: 36732

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGIT
CCCCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHH
TTINEALVDADVSMEDIDAIAVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHI
HHHHHHHHCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGETRDDAVGEAYDKVARTIGLNY
HHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
PGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
CCCCCHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHH
TSFQNSVVEVLTFKAIQACKEYSVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPK
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCC
LCTDNAAMIGVAGHSLYQQGRFADLALNGHSNIDLEEYSAE
CCCCCCEEEEECCHHHHHCCCEEEEEECCCCCCCHHHCCCC
>Mature Secondary Structure 
TKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGIT
CCCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHH
TTINEALVDADVSMEDIDAIAVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHI
HHHHHHHHCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGETRDDAVGEAYDKVARTIGLNY
HHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
PGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
CCCCCHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHH
TSFQNSVVEVLTFKAIQACKEYSVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPK
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCC
LCTDNAAMIGVAGHSLYQQGRFADLALNGHSNIDLEEYSAE
CCCCCCEEEEECCHHHHHCCCEEEEEECCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA