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The map label for this gene is sugE [H]

Identifier: 154248122

GI number: 154248122

Start: 4652759

End: 4653076

Strand: Direct

Name: sugE [H]

Synonym: Xaut_4202

Alternate gene names: 154248122

Gene position: 4652759-4653076 (Clockwise)

Preceding gene: 154248121

Following gene: 154248123

Centisome position: 87.64

GC content: 65.72

Gene sequence:

>318_bases
ATGGCGTGGATCTATCTGTTCGTCGCCGGTGTCATGGAAATCGCCTGGGCCATCGGCATGAAGCAGTCGGAAGGCTTCAC
CCGGCTGTGGCCCAGCGTCTTCACCCTGTCGGCCATCGCCGTCAGTCTGTTCCTGCTGTCGCTGGCGCTCAGGGGCATTC
CCATCGGCACCGCCTATGCGGTGTGGGCGGGGATCGGCACCGTGGGCACGGCGCTCGTCGGCATTCTCTTCTTCTCCGAA
TCCACCGACCTGCTGCGGCTCGCCTCCATCGGCCTCATCGGCGCCGGGATCGTGGGGCTGAAGCTGGTCACGCCCTGA

Upstream 100 bases:

>100_bases
AATGAGGGCAGGGGACATTCGTCCCCGATGGGACGCGGACGGCCGCGTGCCCTTGCGTATCGAGCGGCGGGGACGACCTC
GCCACCCGAGGTACCCGCCA

Downstream 100 bases:

>100_bases
CGAACCGACTAGTTTGGCGCGCCGCCGGGGCCTCACTGTAAAGCGTTGCCCGGCGGCGCTGCTTCCAAGGATGATCCCAT
GACCGCCGCACCGCCCGCCA

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MAWIYLFVAGVMEIAWAIGMKQSEGFTRLWPSVFTLSAIAVSLFLLSLALRGIPIGTAYAVWAGIGTVGTALVGILFFSE
STDLLRLASIGLIGAGIVGLKLVTP

Sequences:

>Translated_105_residues
MAWIYLFVAGVMEIAWAIGMKQSEGFTRLWPSVFTLSAIAVSLFLLSLALRGIPIGTAYAVWAGIGTVGTALVGILFFSE
STDLLRLASIGLIGAGIVGLKLVTP
>Mature_104_residues
AWIYLFVAGVMEIAWAIGMKQSEGFTRLWPSVFTLSAIAVSLFLLSLALRGIPIGTAYAVWAGIGTVGTALVGILFFSES
TDLLRLASIGLIGAGIVGLKLVTP

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=53.8461538461538, Blast_Score=114, Evalue=1e-27,
Organism=Escherichia coli, GI1786755, Length=102, Percent_Identity=42.156862745098, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11030; Mature: 10899

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWIYLFVAGVMEIAWAIGMKQSEGFTRLWPSVFTLSAIAVSLFLLSLALRGIPIGTAYA
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
VWAGIGTVGTALVGILFFSESTDLLRLASIGLIGAGIVGLKLVTP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHEEEECC
>Mature Secondary Structure 
AWIYLFVAGVMEIAWAIGMKQSEGFTRLWPSVFTLSAIAVSLFLLSLALRGIPIGTAYA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
VWAGIGTVGTALVGILFFSESTDLLRLASIGLIGAGIVGLKLVTP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]