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The map label for this gene is ptxB [H]

Identifier: 154247885

GI number: 154247885

Start: 4385548

End: 4386516

Strand: Direct

Name: ptxB [H]

Synonym: Xaut_3962

Alternate gene names: 154247885

Gene position: 4385548-4386516 (Clockwise)

Preceding gene: 154247884

Following gene: 154247886

Centisome position: 82.61

GC content: 60.47

Gene sequence:

>969_bases
ATGACGCTACCGCGCTTTCTCGCACGCACCCTCATGCTTGCCGCCATGTGTCTGGGGCCAAGCATCGCCCATGCTGACTT
CAAGCTCGATCCACGCTTCACGGACGCGAATGGCGACATGGTCGCGGACGCGCCCACTGATCCTTCCAAGCAGATCGACC
CGGACACGCTGATCTTCTCCTACACCCCCGTTGAGGATCCGGCCGTCTACGCCAAGGTGTGGCAGGAATTCACCGACCAT
CTTGCGAAGGTGACCGGCAAGAAGGTGCAGTTCTTCCCCGTGCAGTCCAACGCCGCCCAGCTCGAAGCCATGCGTGCCGG
GCGCCTGCATGTGGCCGGCTTCAACACCGGCTCCAATCCCATCGCCGTCGCCTGCTCCGGCTTTGTGCCTTTCGCCATGA
TGGCCTCGAAGGATGGCGCCTACGGCTATGAGATGGAGATCATCACCTATCCCGGCTCCGGCATCACTAAGGTTGAAGAC
ATCAAGGGTAAGAAGATGGCCTTCACCTCGGAGACCTCCAATTCCGGCTACAAGGCGCCGTCCGCGCTGCTGCGCTCGCA
GTTCGGCATGGAGGCGGGCAAGGATTACGAACCCGCCTTCTCCGGCAAGCACGACAATTCCATCATCGGCGTCGCCAACA
AGGATTATCCGGCAGCGGCCGTCGCCAATTCGGTGATGAAGCGCATGATCGCCCGCGGCGTGATCAAACCCGAGCAGGTG
GTTACCATCTACAAGTCGCAGACCTTCCCCACCACCGGCTATGGCTATGCCTACAATCTGAAGCCCGAGCTTGCCGCCAA
GGTGAAAGAGGCGTTCTTCAGCTTCAATTGGGATGGCACTGCTCTCCTGAAGGAGTTCCAGTCGGCCGAGCCGCCGCAGG
AGAAATTCATTTCCATCACCTTCAAGGAGACCTGGGCGGTGGTGCGCCAGGTCGATGACGCCATGGGCGTCAGCTACGCC
TGCAAGTAA

Upstream 100 bases:

>100_bases
CCAGCCGATGGGAACGCCGGCACCGAGCAGATAAGGCTCCGACTTCGAGTTCGCGTACCAGCATCGTCCGATTGAATTAC
ACCGCCACTGGAGAGAAGAG

Downstream 100 bases:

>100_bases
ACTCTGGAGAGAGGGACTGTGGGATGCTGACCATCGCCGGTCTGTCCAAGCGCTACGCCAAGGGGGACAAGGCCCTCGAT
GATGTTTCGCTCAGCATCCC

Product: phosphonate ABC transporter periplasmic phosphonate-binding protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTLPRFLARTLMLAAMCLGPSIAHADFKLDPRFTDANGDMVADAPTDPSKQIDPDTLIFSYTPVEDPAVYAKVWQEFTDH
LAKVTGKKVQFFPVQSNAAQLEAMRAGRLHVAGFNTGSNPIAVACSGFVPFAMMASKDGAYGYEMEIITYPGSGITKVED
IKGKKMAFTSETSNSGYKAPSALLRSQFGMEAGKDYEPAFSGKHDNSIIGVANKDYPAAAVANSVMKRMIARGVIKPEQV
VTIYKSQTFPTTGYGYAYNLKPELAAKVKEAFFSFNWDGTALLKEFQSAEPPQEKFISITFKETWAVVRQVDDAMGVSYA
CK

Sequences:

>Translated_322_residues
MTLPRFLARTLMLAAMCLGPSIAHADFKLDPRFTDANGDMVADAPTDPSKQIDPDTLIFSYTPVEDPAVYAKVWQEFTDH
LAKVTGKKVQFFPVQSNAAQLEAMRAGRLHVAGFNTGSNPIAVACSGFVPFAMMASKDGAYGYEMEIITYPGSGITKVED
IKGKKMAFTSETSNSGYKAPSALLRSQFGMEAGKDYEPAFSGKHDNSIIGVANKDYPAAAVANSVMKRMIARGVIKPEQV
VTIYKSQTFPTTGYGYAYNLKPELAAKVKEAFFSFNWDGTALLKEFQSAEPPQEKFISITFKETWAVVRQVDDAMGVSYA
CK
>Mature_321_residues
TLPRFLARTLMLAAMCLGPSIAHADFKLDPRFTDANGDMVADAPTDPSKQIDPDTLIFSYTPVEDPAVYAKVWQEFTDHL
AKVTGKKVQFFPVQSNAAQLEAMRAGRLHVAGFNTGSNPIAVACSGFVPFAMMASKDGAYGYEMEIITYPGSGITKVEDI
KGKKMAFTSETSNSGYKAPSALLRSQFGMEAGKDYEPAFSGKHDNSIIGVANKDYPAAAVANSVMKRMIARGVIKPEQVV
TIYKSQTFPTTGYGYAYNLKPELAAKVKEAFFSFNWDGTALLKEFQSAEPPQEKFISITFKETWAVVRQVDDAMGVSYAC
K

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 35154; Mature: 35023

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPRFLARTLMLAAMCLGPSIAHADFKLDPRFTDANGDMVADAPTDPSKQIDPDTLIFS
CCHHHHHHHHHHHHHHHHCCCEECCCEEECCCEECCCCCEEECCCCCCCCCCCCCEEEEE
YTPVEDPAVYAKVWQEFTDHLAKVTGKKVQFFPVQSNAAQLEAMRAGRLHVAGFNTGSNP
ECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCEEEEEECCCCCCC
IAVACSGFVPFAMMASKDGAYGYEMEIITYPGSGITKVEDIKGKKMAFTSETSNSGYKAP
EEEEECCCCHHHHEECCCCCCEEEEEEEEECCCCCCCHHHCCCCEEEEECCCCCCCCCCH
SALLRSQFGMEAGKDYEPAFSGKHDNSIIGVANKDYPAAAVANSVMKRMIARGVIKPEQV
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHE
VTIYKSQTFPTTGYGYAYNLKPELAAKVKEAFFSFNWDGTALLKEFQSAEPPQEKFISIT
EEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHEEEEE
FKETWAVVRQVDDAMGVSYACK
HHHHHHHHHHHHHHHCCEEECC
>Mature Secondary Structure 
TLPRFLARTLMLAAMCLGPSIAHADFKLDPRFTDANGDMVADAPTDPSKQIDPDTLIFS
CHHHHHHHHHHHHHHHHCCCEECCCEEECCCEECCCCCEEECCCCCCCCCCCCCEEEEE
YTPVEDPAVYAKVWQEFTDHLAKVTGKKVQFFPVQSNAAQLEAMRAGRLHVAGFNTGSNP
ECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCEEEEEECCCCCCC
IAVACSGFVPFAMMASKDGAYGYEMEIITYPGSGITKVEDIKGKKMAFTSETSNSGYKAP
EEEEECCCCHHHHEECCCCCCEEEEEEEEECCCCCCCHHHCCCCEEEEECCCCCCCCCCH
SALLRSQFGMEAGKDYEPAFSGKHDNSIIGVANKDYPAAAVANSVMKRMIARGVIKPEQV
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHE
VTIYKSQTFPTTGYGYAYNLKPELAAKVKEAFFSFNWDGTALLKEFQSAEPPQEKFISIT
EEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHEEEEE
FKETWAVVRQVDDAMGVSYACK
HHHHHHHHHHHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]