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The map label for this gene is gap3 [H]

Identifier: 154247883

GI number: 154247883

Start: 4383180

End: 4384220

Strand: Direct

Name: gap3 [H]

Synonym: Xaut_3960

Alternate gene names: 154247883

Gene position: 4383180-4384220 (Clockwise)

Preceding gene: 154247882

Following gene: 154247884

Centisome position: 82.56

GC content: 67.92

Gene sequence:

>1041_bases
ATGAGAGTAGGGATCAACGGCCTCGGCCGCATCGGACGGTTGTCGCTGCGCGCGGCCATGGGGGCGGCGCAGCGCCCGGA
CAACGACCCGCGCGGCAACAACCGGCTCGACATCGTCCATCTCAACGAGATCAAGGGCGGCGCGGAAGCTATCGCCCATC
TCCTCGAGTTCGACAGCGTGCAGGGGCGCTGGCGCGCGCCCATCTCCCATGATGAGGGGAGCGTGCGCATCGGGGACAAG
GCCATGTCCTTCTCCGCCCATGCCGCCCCCACCGACATCCCCTGGGGCGATCTCGGCGTGGACGTGGTGCTGGAATCCAC
CGGCAAGTTCCTGACGCCGCAGGTGCTCGAAGGCCACCTGAAGCGCGGCGCCAAACGTGTCATCGTCGCCGCGCCGGTGA
AGGACCCCTCGGTGCTCAACGTGGTGGTAGGGGTGAACGAAAATCTCTACGACCGCGAGAAGCACCCCATCGTCACCGCC
GCCTCCTGCACCACCAATTGCCTCGCCCCGGTGGTGAAGGTGGTGCACGAGGCCATCGGCATCCGCCACGGCCAGATCAC
CACCATCCACGATCCCACCAACACCAACGTGGTGGTGGACGCGCCCCACAAGGACCTGCGCCGCGCCCGCTCGGCCATGC
TCTCGCTGCAGCCCACCACCACCGGCAGCGCCACCGCCATCGCCCTCATCTATCCCGAGCTGAAGGGCAAGCTGAACGGC
CATGCGGTGCGCGCCCCGGTGCTCAACGCCTCGCTTACCGATTGCGTGTTCGAGCTGAACCGCGAGACCACGGCGGAGGA
GGTGAACGCCCTGTTCACCGAGGCCGCCGCGGGCGCGCTCAACGGCATCCTCGGCTTCGAGCCGCGTCCGCTGGTGTCGG
CGGACTACGCCCGCGACACCCGCTCCGCCATCGTGGACGGACCGTCCACCCTCGTCACCGACGGCACCCTGCTCAAGGTC
TATGCCTGGTACGACAACGAGATGGGCTATGCCTGCCGCATGGTGGACCTCGCCTGCCATCTCGAACGCGTGGGGCTGTG
A

Upstream 100 bases:

>100_bases
GCCGGCGGCGTGAAGGTGACGGATGCAGCCGACCACACCAAGGCCTGAGGTCGTCGCGGCAACGCCGCCCCTTTTCAAAG
TTTGCGAGGATGACGGTGCC

Downstream 100 bases:

>100_bases
GATGGCGGCATCATCCTCCGCGGGCCTACGCAACTACGCCATCGTCACGGCGGCCTATTGGGGCTTCACGCTGACCGACG
GCGCGCTGCGCATGCTGGTG

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRVGINGLGRIGRLSLRAAMGAAQRPDNDPRGNNRLDIVHLNEIKGGAEAIAHLLEFDSVQGRWRAPISHDEGSVRIGDK
AMSFSAHAAPTDIPWGDLGVDVVLESTGKFLTPQVLEGHLKRGAKRVIVAAPVKDPSVLNVVVGVNENLYDREKHPIVTA
ASCTTNCLAPVVKVVHEAIGIRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLNG
HAVRAPVLNASLTDCVFELNRETTAEEVNALFTEAAAGALNGILGFEPRPLVSADYARDTRSAIVDGPSTLVTDGTLLKV
YAWYDNEMGYACRMVDLACHLERVGL

Sequences:

>Translated_346_residues
MRVGINGLGRIGRLSLRAAMGAAQRPDNDPRGNNRLDIVHLNEIKGGAEAIAHLLEFDSVQGRWRAPISHDEGSVRIGDK
AMSFSAHAAPTDIPWGDLGVDVVLESTGKFLTPQVLEGHLKRGAKRVIVAAPVKDPSVLNVVVGVNENLYDREKHPIVTA
ASCTTNCLAPVVKVVHEAIGIRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLNG
HAVRAPVLNASLTDCVFELNRETTAEEVNALFTEAAAGALNGILGFEPRPLVSADYARDTRSAIVDGPSTLVTDGTLLKV
YAWYDNEMGYACRMVDLACHLERVGL
>Mature_346_residues
MRVGINGLGRIGRLSLRAAMGAAQRPDNDPRGNNRLDIVHLNEIKGGAEAIAHLLEFDSVQGRWRAPISHDEGSVRIGDK
AMSFSAHAAPTDIPWGDLGVDVVLESTGKFLTPQVLEGHLKRGAKRVIVAAPVKDPSVLNVVVGVNENLYDREKHPIVTA
ASCTTNCLAPVVKVVHEAIGIRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLNG
HAVRAPVLNASLTDCVFELNRETTAEEVNALFTEAAAGALNGILGFEPRPLVSADYARDTRSAIVDGPSTLVTDGTLLKV
YAWYDNEMGYACRMVDLACHLERVGL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=342, Percent_Identity=37.1345029239766, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI7657116, Length=342, Percent_Identity=37.1345029239766, Blast_Score=230, Evalue=1e-60,
Organism=Escherichia coli, GI1788079, Length=344, Percent_Identity=36.9186046511628, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789295, Length=346, Percent_Identity=37.8612716763006, Blast_Score=238, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17568413, Length=345, Percent_Identity=36.8115942028986, Blast_Score=230, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI32566163, Length=345, Percent_Identity=36.8115942028986, Blast_Score=230, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI17534677, Length=350, Percent_Identity=35.7142857142857, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17534679, Length=350, Percent_Identity=35.4285714285714, Blast_Score=219, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6321631, Length=344, Percent_Identity=38.3720930232558, Blast_Score=255, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6322468, Length=344, Percent_Identity=37.7906976744186, Blast_Score=252, Evalue=6e-68,
Organism=Saccharomyces cerevisiae, GI6322409, Length=344, Percent_Identity=37.5, Blast_Score=249, Evalue=6e-67,
Organism=Drosophila melanogaster, GI85725000, Length=344, Percent_Identity=37.2093023255814, Blast_Score=230, Evalue=9e-61,
Organism=Drosophila melanogaster, GI22023983, Length=344, Percent_Identity=37.2093023255814, Blast_Score=230, Evalue=9e-61,
Organism=Drosophila melanogaster, GI17933600, Length=344, Percent_Identity=36.9186046511628, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI18110149, Length=344, Percent_Identity=36.9186046511628, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI19922412, Length=343, Percent_Identity=35.2769679300292, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37114; Mature: 37114

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGINGLGRIGRLSLRAAMGAAQRPDNDPRGNNRLDIVHLNEIKGGAEAIAHLLEFDSV
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCC
QGRWRAPISHDEGSVRIGDKAMSFSAHAAPTDIPWGDLGVDVVLESTGKFLTPQVLEGHL
CCCCCCCCCCCCCCEEECCHHEECCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
KRGAKRVIVAAPVKDPSVLNVVVGVNENLYDREKHPIVTAASCTTNCLAPVVKVVHEAIG
HCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
IRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLNG
CCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHEEECCCCCCCCEEEEEEEECCCCCCCC
HAVRAPVLNASLTDCVFELNRETTAEEVNALFTEAAAGALNGILGFEPRPLVSADYARDT
CEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCH
RSAIVDGPSTLVTDGTLLKVYAWYDNEMGYACRMVDLACHLERVGL
HHHHCCCCCEEEECCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVGINGLGRIGRLSLRAAMGAAQRPDNDPRGNNRLDIVHLNEIKGGAEAIAHLLEFDSV
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCC
QGRWRAPISHDEGSVRIGDKAMSFSAHAAPTDIPWGDLGVDVVLESTGKFLTPQVLEGHL
CCCCCCCCCCCCCCEEECCHHEECCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
KRGAKRVIVAAPVKDPSVLNVVVGVNENLYDREKHPIVTAASCTTNCLAPVVKVVHEAIG
HCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
IRHGQITTIHDPTNTNVVVDAPHKDLRRARSAMLSLQPTTTGSATAIALIYPELKGKLNG
CCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHEEECCCCCCCCEEEEEEEECCCCCCCC
HAVRAPVLNASLTDCVFELNRETTAEEVNALFTEAAAGALNGILGFEPRPLVSADYARDT
CEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCH
RSAIVDGPSTLVTDGTLLKVYAWYDNEMGYACRMVDLACHLERVGL
HHHHCCCCCEEEECCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]