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The map label for this gene is arsR [H]

Identifier: 154247864

GI number: 154247864

Start: 4363997

End: 4364296

Strand: Direct

Name: arsR [H]

Synonym: Xaut_3941

Alternate gene names: 154247864

Gene position: 4363997-4364296 (Clockwise)

Preceding gene: 154247862

Following gene: 154247865

Centisome position: 82.2

GC content: 66.33

Gene sequence:

>300_bases
ATGCAGTCCGCCCTCACCCTTCTGTCGGCCCTGGCCGAACCCACCCGCCTCGCGGCGGTCCGCCTCCTGTGGGATGGGCA
CGAGCATTGCGTCTGCGAACTCGTGCGCGTCCTCGGCGTCACCCAATCCCGCATGTCGCGCCATATGGCGGTGCTCAAGC
AGGCTGGCGTCGTGGTGGATCGGCGGGACGCCCAATGGGTGCGCTACCGTCGCAATCCCGAACTGCCGGCCGAGCAGGCA
ACCATCATCAATGCTGTCCTCACCACCCTGGACGCTTCATCGAACAGGAGAGCCGCATGA

Upstream 100 bases:

>100_bases
GTTCAATTCTCCCCTGATTTCGAGAAGCCCTGCGTTCCCAGTGACAAGCTAATTATAAAATGCGCTTGAACGCATATGCG
CATTAAAGTAAAAGAAGCGT

Downstream 100 bases:

>100_bases
GCGCCGACCTGTCATTGACCGGGCGCAAGCCGCAGCGGGAGGCATCGCCTCTGGCCTGGGCGGCGGCGACCGTCGCGGCG
ATCGCGCTCTGGTTCGTGGT

Product: regulatory protein ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 99; Mature: 99

Protein sequence:

>99_residues
MQSALTLLSALAEPTRLAAVRLLWDGHEHCVCELVRVLGVTQSRMSRHMAVLKQAGVVVDRRDAQWVRYRRNPELPAEQA
TIINAVLTTLDASSNRRAA

Sequences:

>Translated_99_residues
MQSALTLLSALAEPTRLAAVRLLWDGHEHCVCELVRVLGVTQSRMSRHMAVLKQAGVVVDRRDAQWVRYRRNPELPAEQA
TIINAVLTTLDASSNRRAA
>Mature_99_residues
MQSALTLLSALAEPTRLAAVRLLWDGHEHCVCELVRVLGVTQSRMSRHMAVLKQAGVVVDRRDAQWVRYRRNPELPAEQA
TIINAVLTTLDASSNRRAA

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=80, Percent_Identity=42.5, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11031; Mature: 11031

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSALTLLSALAEPTRLAAVRLLWDGHEHCVCELVRVLGVTQSRMSRHMAVLKQAGVVVD
CCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEE
RRDAQWVRYRRNPELPAEQATIINAVLTTLDASSNRRAA
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQSALTLLSALAEPTRLAAVRLLWDGHEHCVCELVRVLGVTQSRMSRHMAVLKQAGVVVD
CCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEE
RRDAQWVRYRRNPELPAEQATIINAVLTTLDASSNRRAA
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]