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The map label for this gene is era [H]

Identifier: 154247805

GI number: 154247805

Start: 4300721

End: 4301878

Strand: Direct

Name: era [H]

Synonym: Xaut_3882

Alternate gene names: 154247805

Gene position: 4300721-4301878 (Clockwise)

Preceding gene: 154247804

Following gene: 154247810

Centisome position: 81.01

GC content: 67.36

Gene sequence:

>1158_bases
ATGGCACCGGCAGGGAGGGGTCCCAAGGGCCCCAAGAACAGCCCGGATAAGAACAGCCCGGATGAGAGCGGCCCCGGCAA
CGGCGCTCCGGCCAGTGATGTGTCGAGCGCGGCCCAAGGGTCGCCGCAGGACGCGGAGCACGAGCTGCCGGAGGACGAAC
TGCCGGAGGGCGCCCTGTCCGACGAGGACTTCGACGACGAGGACGACGATTTCGACGAGGAGCACGATGTCGCGCCGCGC
GTCCTGCCGCCTCTTGAGGGACCGACCCGCTGCGGCTTCGTCGCGCTTCTGGGCGCGCCCAATGCGGGCAAGTCCACGCT
GACCAACCAGTTGGTGGGCACCAAGGTGTCCATCGTCTCCCACAAGGTGCAGACCACCCGCGCCATTGTGCGCGGCATCG
CGCTCGATGGCGCGGCCCAGCTGGTGCTGGTGGACACCCCCGGCATCTTCTCGCCCAAGCGCCGGCTGGAGCGCGCCATG
GTGTCCAGCGCCTGGACTCATGCCGCCGACGCCGACGTGATCGCGCTGCTGGTGGACGCCAAGCGCGGCCTGGACGAGGA
CATCGAGGCCCTGCTTGCCCCGCTCTCGCAGATCCACAAGCCGCGGGCGCTGATTCTCAACAAGATCGACATCATCCGCC
GCGACACGCTGCTGGCGCTTGCCGCGCAGATCAACGAGAAGCTGGCGTTCGACCGGGTGTTCATGGTCTCCGCCCTGACC
GGCGACGGGGTTGCCGACGTGCGCCGCTGGTTCGCCGAGCAGGTGCCGCTCAGCCCCTGGCTCTATCCGGAGGACCAGGT
GTCGGATGCGCCCATGCGCATGCTGGCGGCGGAAATCACCCGGGAAAAGATGTTCCTGCGCCTGCACGACGAGCTGCCCT
ACCGCTCCACGGTGGAAACCGAGAGCTGGAAGGAGTTGCGCAACGGCTCCGTGCGCATCGAGCAGACCATCTATGTGGAG
CGCGAAAGCCAGCGCAAGATCGTGCTTGGCAAGGGCGGCAGCACCATCAAGACCATCTCCTCGGAATCCCGGGCGGAGAT
TGCCGGGATCATCGAGCAGCCGGTGCACCTGTTCCTGTTCGTGAAGGTGCGCGAAAGCTGGGCGGACGACCCCGAACGCT
ACCGCGAGATGGGGCTGGAATTTCCCAAGGGCGGCTGA

Upstream 100 bases:

>100_bases
CCTCCGAGCAGGCGGACGGGGCCTCCAAGCAGAATGCGCAGAAGGCGGCAGCCGCCGCTTTCCTCGTCCGTGAGGGCGTG
TGGAAAAAGGACGAGTCGTG

Downstream 100 bases:

>100_bases
ACGGGGCTGAAGGCGGGCGGCTCTTCGGCCGCCATCGTATCAGACGTGCGCGCCCCTCAGACCTCCGCGCCGAGACCTTG
CCGGGCCTTGTCCAGCTCCT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAPAGRGPKGPKNSPDKNSPDESGPGNGAPASDVSSAAQGSPQDAEHELPEDELPEGALSDEDFDDEDDDFDEEHDVAPR
VLPPLEGPTRCGFVALLGAPNAGKSTLTNQLVGTKVSIVSHKVQTTRAIVRGIALDGAAQLVLVDTPGIFSPKRRLERAM
VSSAWTHAADADVIALLVDAKRGLDEDIEALLAPLSQIHKPRALILNKIDIIRRDTLLALAAQINEKLAFDRVFMVSALT
GDGVADVRRWFAEQVPLSPWLYPEDQVSDAPMRMLAAEITREKMFLRLHDELPYRSTVETESWKELRNGSVRIEQTIYVE
RESQRKIVLGKGGSTIKTISSESRAEIAGIIEQPVHLFLFVKVRESWADDPERYREMGLEFPKGG

Sequences:

>Translated_385_residues
MAPAGRGPKGPKNSPDKNSPDESGPGNGAPASDVSSAAQGSPQDAEHELPEDELPEGALSDEDFDDEDDDFDEEHDVAPR
VLPPLEGPTRCGFVALLGAPNAGKSTLTNQLVGTKVSIVSHKVQTTRAIVRGIALDGAAQLVLVDTPGIFSPKRRLERAM
VSSAWTHAADADVIALLVDAKRGLDEDIEALLAPLSQIHKPRALILNKIDIIRRDTLLALAAQINEKLAFDRVFMVSALT
GDGVADVRRWFAEQVPLSPWLYPEDQVSDAPMRMLAAEITREKMFLRLHDELPYRSTVETESWKELRNGSVRIEQTIYVE
RESQRKIVLGKGGSTIKTISSESRAEIAGIIEQPVHLFLFVKVRESWADDPERYREMGLEFPKGG
>Mature_384_residues
APAGRGPKGPKNSPDKNSPDESGPGNGAPASDVSSAAQGSPQDAEHELPEDELPEGALSDEDFDDEDDDFDEEHDVAPRV
LPPLEGPTRCGFVALLGAPNAGKSTLTNQLVGTKVSIVSHKVQTTRAIVRGIALDGAAQLVLVDTPGIFSPKRRLERAMV
SSAWTHAADADVIALLVDAKRGLDEDIEALLAPLSQIHKPRALILNKIDIIRRDTLLALAAQINEKLAFDRVFMVSALTG
DGVADVRRWFAEQVPLSPWLYPEDQVSDAPMRMLAAEITREKMFLRLHDELPYRSTVETESWKELRNGSVRIEQTIYVER
ESQRKIVLGKGGSTIKTISSESRAEIAGIIEQPVHLFLFVKVRESWADDPERYREMGLEFPKGG

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=343, Percent_Identity=30.3206997084548, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1788919, Length=296, Percent_Identity=39.1891891891892, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI87082120, Length=161, Percent_Identity=29.8136645962733, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532761, Length=157, Percent_Identity=36.3057324840764, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646434, Length=331, Percent_Identity=29.607250755287, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42149; Mature: 42018

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPAGRGPKGPKNSPDKNSPDESGPGNGAPASDVSSAAQGSPQDAEHELPEDELPEGALS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCCHHHCCCCCCC
DEDFDDEDDDFDEEHDVAPRVLPPLEGPTRCGFVALLGAPNAGKSTLTNQLVGTKVSIVS
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHH
HKVQTTRAIVRGIALDGAAQLVLVDTPGIFSPKRRLERAMVSSAWTHAADADVIALLVDA
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHH
KRGLDEDIEALLAPLSQIHKPRALILNKIDIIRRDTLLALAAQINEKLAFDRVFMVSALT
HCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHC
GDGVADVRRWFAEQVPLSPWLYPEDQVSDAPMRMLAAEITREKMFLRLHDELPYRSTVET
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ESWKELRNGSVRIEQTIYVERESQRKIVLGKGGSTIKTISSESRAEIAGIIEQPVHLFLF
HHHHHHHCCCEEEEEEEEEEECCCCEEEEECCCCEEEECCCCHHHHHHHHHHCCCEEEEE
VKVRESWADDPERYREMGLEFPKGG
EEEHHHCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
APAGRGPKGPKNSPDKNSPDESGPGNGAPASDVSSAAQGSPQDAEHELPEDELPEGALS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCCHHHCCCCCCC
DEDFDDEDDDFDEEHDVAPRVLPPLEGPTRCGFVALLGAPNAGKSTLTNQLVGTKVSIVS
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHH
HKVQTTRAIVRGIALDGAAQLVLVDTPGIFSPKRRLERAMVSSAWTHAADADVIALLVDA
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHH
KRGLDEDIEALLAPLSQIHKPRALILNKIDIIRRDTLLALAAQINEKLAFDRVFMVSALT
HCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHC
GDGVADVRRWFAEQVPLSPWLYPEDQVSDAPMRMLAAEITREKMFLRLHDELPYRSTVET
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ESWKELRNGSVRIEQTIYVERESQRKIVLGKGGSTIKTISSESRAEIAGIIEQPVHLFLF
HHHHHHHCCCEEEEEEEEEEECCCCEEEEECCCCEEEECCCCHHHHHHHHHHCCCEEEEE
VKVRESWADDPERYREMGLEFPKGG
EEEHHHCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA