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The map label for this gene is lepB [H]

Identifier: 154247803

GI number: 154247803

Start: 4299262

End: 4300014

Strand: Direct

Name: lepB [H]

Synonym: Xaut_3880

Alternate gene names: 154247803

Gene position: 4299262-4300014 (Clockwise)

Preceding gene: 154247802

Following gene: 154247804

Centisome position: 80.98

GC content: 61.35

Gene sequence:

>753_bases
ATGACCGCGACCAGCGACTCCAAGAAGGACGGCGGTTTCCTCGAAACCGTCCGCGTGATCGTCCATGCGCTTCTGATTGC
GCTGGTGATCCGGACCTTCCTGTTCCAGCCTTTCAACATCCCGTCCGGGTCCATGAAGGACACCCTGCTGATCGGCGACT
ATCTCTTCGTCTCCAAGTACAGCTACGGCTATTCGCGCTTCTCGATCCCATTCTCGCCCAACCTGTTCTCCGGCCGCATC
TTCGGCTCGGAGCCCACGCGCGGCGACGTGGTGGTGTTCAAGCTGCCGCGCGACAACGAGACGGACTACATCAAGCGCGT
CATCGGCATGCCCGGCGACAAGATCCAGATGATCGGTGGCCTTTTGCACATCAACGGCACGCCGGTGCAGCGTGAGCGCC
TTCCCGACGTGTCGGAGGATGACGGCACCGGCCGCAAGGTCCCGGTGAAGCGCTGGCGCGAGACCCTGCCCAACGGCGTC
TCCTTCGAGACCCTCGATCTGGTGGATAACGGCTTCTACGACAACACCCCCGTCTATGACGTGCCTCCGGGCCACTACTT
CATGATGGGCGATAATCGTGATAACTCGGCGGACAGCCGGGTTTTGAGCCAGGTCGGCTACGTTCCCTTCGAGAATCTCA
TCGGCAAGGCGCAGGTGATCTTCTTCTCGGTCGACGAGGGCGCGTCCGCGTGGCAGGTTTGGACTTGGCCTTGGACGGTG
CGATGGGATCGGCTGTTCTCTCGGGTACATTGA

Upstream 100 bases:

>100_bases
ACCTTGGCCCTGTGGACACGGGCGCCGATCCGGCGTCTCTCCTCAGTTTCGGCGCAGTTTCATCTACCCTGCGCCTCACC
CGGGATTTTTTGGACAACAG

Downstream 100 bases:

>100_bases
ACGCGGTGGGCTCTGACCTCGCGTCCGTAGAAGAGCGGATCGGATATCGCTTCCGTGACCGGTCGATCCTTGAGCTCGCG
CTCTCCCACATCAGCGCCGT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTATSDSKKDGGFLETVRVIVHALLIALVIRTFLFQPFNIPSGSMKDTLLIGDYLFVSKYSYGYSRFSIPFSPNLFSGRI
FGSEPTRGDVVVFKLPRDNETDYIKRVIGMPGDKIQMIGGLLHINGTPVQRERLPDVSEDDGTGRKVPVKRWRETLPNGV
SFETLDLVDNGFYDNTPVYDVPPGHYFMMGDNRDNSADSRVLSQVGYVPFENLIGKAQVIFFSVDEGASAWQVWTWPWTV
RWDRLFSRVH

Sequences:

>Translated_250_residues
MTATSDSKKDGGFLETVRVIVHALLIALVIRTFLFQPFNIPSGSMKDTLLIGDYLFVSKYSYGYSRFSIPFSPNLFSGRI
FGSEPTRGDVVVFKLPRDNETDYIKRVIGMPGDKIQMIGGLLHINGTPVQRERLPDVSEDDGTGRKVPVKRWRETLPNGV
SFETLDLVDNGFYDNTPVYDVPPGHYFMMGDNRDNSADSRVLSQVGYVPFENLIGKAQVIFFSVDEGASAWQVWTWPWTV
RWDRLFSRVH
>Mature_249_residues
TATSDSKKDGGFLETVRVIVHALLIALVIRTFLFQPFNIPSGSMKDTLLIGDYLFVSKYSYGYSRFSIPFSPNLFSGRIF
GSEPTRGDVVVFKLPRDNETDYIKRVIGMPGDKIQMIGGLLHINGTPVQRERLPDVSEDDGTGRKVPVKRWRETLPNGVS
FETLDLVDNGFYDNTPVYDVPPGHYFMMGDNRDNSADSRVLSQVGYVPFENLIGKAQVIFFSVDEGASAWQVWTWPWTVR
WDRLFSRVH

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=285, Percent_Identity=35.4385964912281, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28342; Mature: 28210

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATSDSKKDGGFLETVRVIVHALLIALVIRTFLFQPFNIPSGSMKDTLLIGDYLFVSKY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEECC
SYGYSRFSIPFSPNLFSGRIFGSEPTRGDVVVFKLPRDNETDYIKRVIGMPGDKIQMIGG
CCCCEEEECCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEEE
LLHINGTPVQRERLPDVSEDDGTGRKVPVKRWRETLPNGVSFETLDLVDNGFYDNTPVYD
EEEECCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEHHHCCCCCCCCEEE
VPPGHYFMMGDNRDNSADSRVLSQVGYVPFENLIGKAQVIFFSVDEGASAWQVWTWPWTV
CCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCEEEEEECCEEE
RWDRLFSRVH
EHHHHHHHCC
>Mature Secondary Structure 
TATSDSKKDGGFLETVRVIVHALLIALVIRTFLFQPFNIPSGSMKDTLLIGDYLFVSKY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEECC
SYGYSRFSIPFSPNLFSGRIFGSEPTRGDVVVFKLPRDNETDYIKRVIGMPGDKIQMIGG
CCCCEEEECCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEEE
LLHINGTPVQRERLPDVSEDDGTGRKVPVKRWRETLPNGVSFETLDLVDNGFYDNTPVYD
EEEECCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEHHHCCCCCCCCEEE
VPPGHYFMMGDNRDNSADSRVLSQVGYVPFENLIGKAQVIFFSVDEGASAWQVWTWPWTV
CCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCEEEEEECCEEE
RWDRLFSRVH
EHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA