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The map label for this gene is oprF [H]

Identifier: 154247748

GI number: 154247748

Start: 4244441

End: 4246630

Strand: Direct

Name: oprF [H]

Synonym: Xaut_3825

Alternate gene names: 154247748

Gene position: 4244441-4246630 (Clockwise)

Preceding gene: 154247747

Following gene: 154247749

Centisome position: 79.95

GC content: 74.02

Gene sequence:

>2190_bases
ATGGTTTCAGCGGACGGGCACGAACCCAGGCCCCGGCGCGGGCGCGGCACGGCGTGGCCGGGCCTGTGGCCGCTGCTGCT
CGGCCTCTTCGCCTTCGCCCTGCTGTGCGCCTTCACCCTCGCCGCCGCCCGCGGCCCCATCGAGGCCGACCTCGATTCGG
CGGCCGCCGACATCCTCGCGCGCACCGGGGAGGGCTGGGCCTTCGCCCATTTCGAAGGGCGCGACGCCACGCTGGAGGGC
GAGGCGCTGGCCGAGGAGGCGCGGGCCAAGGTGCGCGGCTCCCTGGCCGGCATGTTCGGCGTCCGGGTGGTGCATGACGC
CACCACCATCCTGCCGGAGCGGCGCCCCTTCACCTTCAGCGCGGTGAAGGACGGCCGCGTCATCGCCCTCGACGGCTATG
TGCCGTCGGCGGAAGCCCTCGCCCGCATCGTGGCGGCCGCCCGTGCCGGCGGCGACCAGGTGACGGGCCAGGAACGGCTG
GTGCGGGCGCGCGGCGCGCCGCCCGGCGATTTCGCCGCCCTGGTCACGTTCGGCCTTGCCCAGCTCAAGAAGCTGCCGTC
CGGCCGCATCACGCTGGCCGATGGGGCCATCGGCATCGAGGGCCGCGCCCGCGACCTTGCGAGCTACGACGCCCTTGCCC
AGACCATGCTCGGCCCCCTGCCGGACGGGATGGTGCTGGCCCGCTTCGCCGTGCGCCCGCCGGTGGCCTCGCCCTTCTTC
TGGTCGGCGGTGCGCGACGGCACGGTGCTGCGGCTGAGCGGCTTCGTGCCCTCGTCTGAGGCGCGCGGCGAGGTGGCCGC
CGCCCTTTCCGCCGCGGTGCCCGGCATTGGCATCAAGGATGACACCCGGCTGGCGGACGGCGCCCCCGCCACCGAGTTGT
GGCTGAAGGCGGTGCGCTTTGCCGGACAGGTGCTGGCGCAACTGCCCGAAGGCCGGGTGACGCTCTCCGACAGCACCATC
GCGGTGGAGGGGGCGGCGCCGAGCTTCCCGGCCTTCGACCAGCTGCTGGCCCAGCGCCGCGCGCCGCCGGACGGCTTCCA
GATCACCCGCTTCGCCGTGGAGCCGCCGCGCGCGGCCCCCTTCGTCTGGCGCATCGAGCGATTGGCCGAGGCGGTGCGGC
TGTCCGGCTACGCGCCCTCGGAGGAGGCCCGTCGGCTGCTGGTGGATGCGACCCGCGCGGCCTTCCCCGGCGTGCAGGTC
TCCGACGACATGCAGCTCGCCTCCGGCGGGCCGGCGCCGGAAGTGTGGGCGAGCACGGCGAGCTTCGCCGTGGCCCAGCT
GGTCAAGCTGCGCACCGGGGCGGCAGACGTGGCGGGCACGAAGGTGACGCTTTCCGGTGAGGCCACCGATTCCGTCACCT
TCCTGTCGGTGATGCAGGCGGTGAAGGCGCCGCCGGCGGGGGTGAGCGTGGTGACGGACGACCTCCAGCCGCCCGCCATC
TCGCCCTATGTGTTCTCGGTGCGCCGGGAGGGCGACGAGCTCACCGTCTCCGGCTTCTATCCGGACGCGGCCGCCCACGC
CGCCATCCGCGCGGCGCTGGAGCGCGACTTCCTGCGCGAAAAGGTGAATGATGTGTCCGCCGTGGGCGGCGGCGCGCCGG
CCGGGTTCCTGCCCGCGGTGCTGTCGGGGCTCACGCAATTGTCGCGCACGGGAACCGGGGAGATCAGCATCGTCGATGGC
CAGCTGCGCCTCACCGGCACCGCCCTGACCTCGGCCGCCGCCAGCGAGATGGACGCCGAGCTGAAGCGGGCCGTGCGCCC
GCCCTTCATGGTGGAGACCGCCATTGACGCGGCCGTCGCCCCGCCGCCGGCGGATACGCCCACGTGCGGCCGGCAGGTGG
GCGAGCTTCTGGCGCGTGGCACCATCCGCTTCGCCAGCGGCAGCGCCGAGATCGACCGGCACAGCCGGGGTCTCATCGAT
CGCCTCGCGGTGGCGCTCAAGCGGTGCCCCACCGCCATGGTGCGCATCCTGGGCCATACCGACGGGGTGGGGGACGCCGA
GTTCAACAAGCGCCTGTCGGAGGCGCGGGCCAATGCGGTGCTCGCCTATCTCGTCACCGCCGGGGTTACCGCCGATCGCC
TCAGCGCGGCGGGTTTCGGCGCCGGCCAGCCGCTGGCGCCCAATGATACCGAGGCGGGCAAGGCGCTGAACCGCCGCATC
GAGTTCGAGGTGAAGGAGCGCGCACCGTGA

Upstream 100 bases:

>100_bases
TCGCAGAAGTGTGCTGAAGTCCCCCGGCCGAAGACGGGTGGCACGTGCCACCCTGCGGCACATGCGGCAGCGCATGCCGG
CGTGAGGGAGACACGGGCGG

Downstream 100 bases:

>100_bases
TCTATCTCACCCTCGCCTTGTGGCCTTATCTTCTGGGGGCGGTGGGAATCGGCCTTGCCACCGGCTATGCGCTCGGCCGG
CTGAACCCGGGGAGGCGTGC

Product: OmpA/MotB domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MVSADGHEPRPRRGRGTAWPGLWPLLLGLFAFALLCAFTLAAARGPIEADLDSAAADILARTGEGWAFAHFEGRDATLEG
EALAEEARAKVRGSLAGMFGVRVVHDATTILPERRPFTFSAVKDGRVIALDGYVPSAEALARIVAAARAGGDQVTGQERL
VRARGAPPGDFAALVTFGLAQLKKLPSGRITLADGAIGIEGRARDLASYDALAQTMLGPLPDGMVLARFAVRPPVASPFF
WSAVRDGTVLRLSGFVPSSEARGEVAAALSAAVPGIGIKDDTRLADGAPATELWLKAVRFAGQVLAQLPEGRVTLSDSTI
AVEGAAPSFPAFDQLLAQRRAPPDGFQITRFAVEPPRAAPFVWRIERLAEAVRLSGYAPSEEARRLLVDATRAAFPGVQV
SDDMQLASGGPAPEVWASTASFAVAQLVKLRTGAADVAGTKVTLSGEATDSVTFLSVMQAVKAPPAGVSVVTDDLQPPAI
SPYVFSVRREGDELTVSGFYPDAAAHAAIRAALERDFLREKVNDVSAVGGGAPAGFLPAVLSGLTQLSRTGTGEISIVDG
QLRLTGTALTSAAASEMDAELKRAVRPPFMVETAIDAAVAPPPADTPTCGRQVGELLARGTIRFASGSAEIDRHSRGLID
RLAVALKRCPTAMVRILGHTDGVGDAEFNKRLSEARANAVLAYLVTAGVTADRLSAAGFGAGQPLAPNDTEAGKALNRRI
EFEVKERAP

Sequences:

>Translated_729_residues
MVSADGHEPRPRRGRGTAWPGLWPLLLGLFAFALLCAFTLAAARGPIEADLDSAAADILARTGEGWAFAHFEGRDATLEG
EALAEEARAKVRGSLAGMFGVRVVHDATTILPERRPFTFSAVKDGRVIALDGYVPSAEALARIVAAARAGGDQVTGQERL
VRARGAPPGDFAALVTFGLAQLKKLPSGRITLADGAIGIEGRARDLASYDALAQTMLGPLPDGMVLARFAVRPPVASPFF
WSAVRDGTVLRLSGFVPSSEARGEVAAALSAAVPGIGIKDDTRLADGAPATELWLKAVRFAGQVLAQLPEGRVTLSDSTI
AVEGAAPSFPAFDQLLAQRRAPPDGFQITRFAVEPPRAAPFVWRIERLAEAVRLSGYAPSEEARRLLVDATRAAFPGVQV
SDDMQLASGGPAPEVWASTASFAVAQLVKLRTGAADVAGTKVTLSGEATDSVTFLSVMQAVKAPPAGVSVVTDDLQPPAI
SPYVFSVRREGDELTVSGFYPDAAAHAAIRAALERDFLREKVNDVSAVGGGAPAGFLPAVLSGLTQLSRTGTGEISIVDG
QLRLTGTALTSAAASEMDAELKRAVRPPFMVETAIDAAVAPPPADTPTCGRQVGELLARGTIRFASGSAEIDRHSRGLID
RLAVALKRCPTAMVRILGHTDGVGDAEFNKRLSEARANAVLAYLVTAGVTADRLSAAGFGAGQPLAPNDTEAGKALNRRI
EFEVKERAP
>Mature_729_residues
MVSADGHEPRPRRGRGTAWPGLWPLLLGLFAFALLCAFTLAAARGPIEADLDSAAADILARTGEGWAFAHFEGRDATLEG
EALAEEARAKVRGSLAGMFGVRVVHDATTILPERRPFTFSAVKDGRVIALDGYVPSAEALARIVAAARAGGDQVTGQERL
VRARGAPPGDFAALVTFGLAQLKKLPSGRITLADGAIGIEGRARDLASYDALAQTMLGPLPDGMVLARFAVRPPVASPFF
WSAVRDGTVLRLSGFVPSSEARGEVAAALSAAVPGIGIKDDTRLADGAPATELWLKAVRFAGQVLAQLPEGRVTLSDSTI
AVEGAAPSFPAFDQLLAQRRAPPDGFQITRFAVEPPRAAPFVWRIERLAEAVRLSGYAPSEEARRLLVDATRAAFPGVQV
SDDMQLASGGPAPEVWASTASFAVAQLVKLRTGAADVAGTKVTLSGEATDSVTFLSVMQAVKAPPAGVSVVTDDLQPPAI
SPYVFSVRREGDELTVSGFYPDAAAHAAIRAALERDFLREKVNDVSAVGGGAPAGFLPAVLSGLTQLSRTGTGEISIVDG
QLRLTGTALTSAAASEMDAELKRAVRPPFMVETAIDAAVAPPPADTPTCGRQVGELLARGTIRFASGSAEIDRHSRGLID
RLAVALKRCPTAMVRILGHTDGVGDAEFNKRLSEARANAVLAYLVTAGVTADRLSAAGFGAGQPLAPNDTEAGKALNRRI
EFEVKERAP

Specific function: Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium [H]

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=104, Percent_Identity=37.5, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006690
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 76110; Mature: 76110

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSADGHEPRPRRGRGTAWPGLWPLLLGLFAFALLCAFTLAAARGPIEADLDSAAADILA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RTGEGWAFAHFEGRDATLEGEALAEEARAKVRGSLAGMFGVRVVHDATTILPERRPFTFS
HCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
AVKDGRVIALDGYVPSAEALARIVAAARAGGDQVTGQERLVRARGAPPGDFAALVTFGLA
EECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHH
QLKKLPSGRITLADGAIGIEGRARDLASYDALAQTMLGPLPDGMVLARFAVRPPVASPFF
HHHHCCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHH
WSAVRDGTVLRLSGFVPSSEARGEVAAALSAAVPGIGIKDDTRLADGAPATELWLKAVRF
HHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AGQVLAQLPEGRVTLSDSTIAVEGAAPSFPAFDQLLAQRRAPPDGFQITRFAVEPPRAAP
HHHHHHHCCCCCEEECCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCH
FVWRIERLAEAVRLSGYAPSEEARRLLVDATRAAFPGVQVSDDMQLASGGPAPEVWASTA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
SFAVAQLVKLRTGAADVAGTKVTLSGEATDSVTFLSVMQAVKAPPAGVSVVTDDLQPPAI
HHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
SPYVFSVRREGDELTVSGFYPDAAAHAAIRAALERDFLREKVNDVSAVGGGAPAGFLPAV
CHHHEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LSGLTQLSRTGTGEISIVDGQLRLTGTALTSAAASEMDAELKRAVRPPFMVETAIDAAVA
HHHHHHHHHCCCCEEEEEECEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHCC
PPPADTPTCGRQVGELLARGTIRFASGSAEIDRHSRGLIDRLAVALKRCPTAMVRILGHT
CCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCC
DGVGDAEFNKRLSEARANAVLAYLVTAGVTADRLSAAGFGAGQPLAPNDTEAGKALNRRI
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCE
EFEVKERAP
EEEECCCCC
>Mature Secondary Structure
MVSADGHEPRPRRGRGTAWPGLWPLLLGLFAFALLCAFTLAAARGPIEADLDSAAADILA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RTGEGWAFAHFEGRDATLEGEALAEEARAKVRGSLAGMFGVRVVHDATTILPERRPFTFS
HCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
AVKDGRVIALDGYVPSAEALARIVAAARAGGDQVTGQERLVRARGAPPGDFAALVTFGLA
EECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHH
QLKKLPSGRITLADGAIGIEGRARDLASYDALAQTMLGPLPDGMVLARFAVRPPVASPFF
HHHHCCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHH
WSAVRDGTVLRLSGFVPSSEARGEVAAALSAAVPGIGIKDDTRLADGAPATELWLKAVRF
HHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AGQVLAQLPEGRVTLSDSTIAVEGAAPSFPAFDQLLAQRRAPPDGFQITRFAVEPPRAAP
HHHHHHHCCCCCEEECCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCH
FVWRIERLAEAVRLSGYAPSEEARRLLVDATRAAFPGVQVSDDMQLASGGPAPEVWASTA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
SFAVAQLVKLRTGAADVAGTKVTLSGEATDSVTFLSVMQAVKAPPAGVSVVTDDLQPPAI
HHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
SPYVFSVRREGDELTVSGFYPDAAAHAAIRAALERDFLREKVNDVSAVGGGAPAGFLPAV
CHHHEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LSGLTQLSRTGTGEISIVDGQLRLTGTALTSAAASEMDAELKRAVRPPFMVETAIDAAVA
HHHHHHHHHCCCCEEEEEECEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHCC
PPPADTPTCGRQVGELLARGTIRFASGSAEIDRHSRGLIDRLAVALKRCPTAMVRILGHT
CCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCC
DGVGDAEFNKRLSEARANAVLAYLVTAGVTADRLSAAGFGAGQPLAPNDTEAGKALNRRI
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCE
EFEVKERAP
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1898935 [H]