Click here to switch to the map view.

The map label for this gene is cobO [H]

Identifier: 154247701

GI number: 154247701

Start: 4184004

End: 4184636

Strand: Direct

Name: cobO [H]

Synonym: Xaut_3777

Alternate gene names: 154247701

Gene position: 4184004-4184636 (Clockwise)

Preceding gene: 154247700

Following gene: 154247702

Centisome position: 78.81

GC content: 69.19

Gene sequence:

>633_bases
GTGAGCGAGCCCGTTCCTCCCCCCGCCGTAGATGACGCCGAGGCCGCCCGCCATCGCGCCAAGATGGAGAAGCGCAAGGC
GGTGCAGGACAAGGAGGTGGCGGAAAAGACCATCGCGAAGGGCCTGCTCATCGTCCATACCGGCCCAGGCAAGGGCAAGA
GCACGGCCGCCTTTGGCCTCGCCCTGCGCATGCTCGGGCGCGGTGGGCGGGTGGGCGTGGTGCAGTTCATCAAGGGCGCG
TGGCAGACCGGCGAGCAGGAGGCCTTCGCCGGGTTCGGCGATCGGGTGGTCTGGCACACCATGGGCGAGGGCTTCACCTG
GGAGACGCAGGACCTCGCCCGTGACCGCGCCGCCGCCGCCCGCGCCTTCGCCAAGGTCCGCGAGCTGATGGCGGACGAGA
CCATCAACCTCCTCGTTCTCGACGAGCTGAACATCGCCCTGCGCTACGACTATCTCGATCTTGGCGAGGTGGTGTCCACC
CTTGCCGCCCGCCGCCCCGGCCTGCACGTGGTGGTGACCGGTCGCAATGCCAAGCCGGAGCTGGTCGCGGCCGCGGATCT
CGTCACCGAGATGGGGCTGGTGAAGCACCATTTTGCGGCCGGCGTGAAGGCGCAGGCCGGGATCGAGTTCTGA

Upstream 100 bases:

>100_bases
GCGACGCCGCCGGCCTCCTCAACCAGCGTCTCGCTGCCCGCGCGCGGCAGGTGGTGCTGGTGGTGGCCGGCCTGCCCCTG
ATCGTGAAGGATGTGACGCC

Downstream 100 bases:

>100_bases
TCGGATGGCACGCGCGCTGATGTTCCAGGGCACCGGGTCGGACGTGGGCAAGTCGCTCCTCGTCGCCGGCCTTGCGCGTG
CCTTCACCCTGCGCGGGCTG

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSEPVPPPAVDDAEAARHRAKMEKRKAVQDKEVAEKTIAKGLLIVHTGPGKGKSTAAFGLALRMLGRGGRVGVVQFIKGA
WQTGEQEAFAGFGDRVVWHTMGEGFTWETQDLARDRAAAARAFAKVRELMADETINLLVLDELNIALRYDYLDLGEVVST
LAARRPGLHVVVTGRNAKPELVAAADLVTEMGLVKHHFAAGVKAQAGIEF

Sequences:

>Translated_210_residues
MSEPVPPPAVDDAEAARHRAKMEKRKAVQDKEVAEKTIAKGLLIVHTGPGKGKSTAAFGLALRMLGRGGRVGVVQFIKGA
WQTGEQEAFAGFGDRVVWHTMGEGFTWETQDLARDRAAAARAFAKVRELMADETINLLVLDELNIALRYDYLDLGEVVST
LAARRPGLHVVVTGRNAKPELVAAADLVTEMGLVKHHFAAGVKAQAGIEF
>Mature_209_residues
SEPVPPPAVDDAEAARHRAKMEKRKAVQDKEVAEKTIAKGLLIVHTGPGKGKSTAAFGLALRMLGRGGRVGVVQFIKGAW
QTGEQEAFAGFGDRVVWHTMGEGFTWETQDLARDRAAAARAFAKVRELMADETINLLVLDELNIALRYDYLDLGEVVSTL
AARRPGLHVVVTGRNAKPELVAAADLVTEMGLVKHHFAAGVKAQAGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=194, Percent_Identity=42.7835051546392, Blast_Score=158, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22650; Mature: 22519

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPVPPPAVDDAEAARHRAKMEKRKAVQDKEVAEKTIAKGLLIVHTGPGKGKSTAAFGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHH
ALRMLGRGGRVGVVQFIKGAWQTGEQEAFAGFGDRVVWHTMGEGFTWETQDLARDRAAAA
HHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
RAFAKVRELMADETINLLVLDELNIALRYDYLDLGEVVSTLAARRPGLHVVVTGRNAKPE
HHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCH
LVAAADLVTEMGLVKHHFAAGVKAQAGIEF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SEPVPPPAVDDAEAARHRAKMEKRKAVQDKEVAEKTIAKGLLIVHTGPGKGKSTAAFGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHH
ALRMLGRGGRVGVVQFIKGAWQTGEQEAFAGFGDRVVWHTMGEGFTWETQDLARDRAAAA
HHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
RAFAKVRELMADETINLLVLDELNIALRYDYLDLGEVVSTLAARRPGLHVVVTGRNAKPE
HHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCH
LVAAADLVTEMGLVKHHFAAGVKAQAGIEF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]