Click here to switch to the map view.

The map label for this gene is pucD [H]

Identifier: 154247684

GI number: 154247684

Start: 4163974

End: 4166268

Strand: Direct

Name: pucD [H]

Synonym: Xaut_3760

Alternate gene names: 154247684

Gene position: 4163974-4166268 (Clockwise)

Preceding gene: 154247683

Following gene: 154247685

Centisome position: 78.43

GC content: 69.93

Gene sequence:

>2295_bases
ATGAGCCGCGTGGTCCATGCTCCCGCCCGCCACGAGAGCGCCAGCGCCCATGTGAGCGGGCGTGCGCTCTATCTCGACGA
CATGCCGGAGCCGCCCGGCCTGCTCCATGGCGTGCTGGTGCTGAGCCCGCACCCCCATGCGCGGATCGTCTCCATCGACC
TCTCCGCCGCCCGTGCCCTGCCCGGCGTGGTGGCGGTGGCGGCGGGGGACGTGCCCGGCGTCAACGACATCGCCCCCATC
CGCACCGGTGAGCCGGCTCTGGCGCAGGGGGTGGTGGAGTATGTGGGTCACCCGGTCGCCGCCGTGGCCGCGCCAACGCT
AGATGAAGCTCGCTCCGCCGCCGCTTTGGTGAAGATCGAATACGAGAAGCTGCCCGCGCTCCTCGACCTCGAAGAAGCCC
TCGCCGCCGGCGCGCGCGTCGCACCCGACCAGATGGTGGGGCGAGGCGATGTGGATGCCGCGCTCGCCGCTGCCCCCCAT
CGCATCACCGGGGAGGTGTGTTGCGGCGGGCAGGATCACTTTTATCTCGAAGGCCAGATCGCCATCGCCGTGCCGGGGGA
GGACCGCGACATGCAGGTCTATTCCTCCACCCAGCACCCCACCGAGGCGCAGCACGGCGTCGCCCATGTGCTCGGGCTGC
CGTTCGCCGCCGTGACCGTGGAGGTGCGGCGCATGGGCGGGGCGTTCGGTGGCAAGGAGAGCCAGGCCACCATCATCGCC
GCCATCGCCGCGCTGCTCGCCCATCACGCGCGAAAGCCGGTGAAACTGCGCCTGCCGCGCGACGTGGACATGGAGGCCAC
CGGCAAGCGCCATCCCTTCCGCATCCGCTGGAATGTGGGCTTCGACAGCGAGGGGCGTCTCGCCGGCCTCGACCTGGAGC
TTGCCGCCGATTGCGGCAATGTGGCGGACCTCTCCCCGGCGGTGGTCTCGCGCGCCCTGTGCCATGCGGACAATTGCTAT
TTCATCCCGGCGGCGCGCTATCGCGGGCTGCTGGTGAAGACCAACACCGTCTCCAACACCGCCTTCCGCGGCTTCGGCGC
GCCGCAGGGGATGCTGGCCATCGAGGCGGTGATGGAGGCCGTCGCCCGCCATCTGGGCCTGCCCATCGAGGAGCTGCGGG
CGGCGAATTTCTATGGCGACGCGCCGCGCAACATCACCCCCTACGGGCAGGAGGTGGAGGACAACATCATCGCCGAGGTG
GTGGCCGAGCTTGACGGCAGGGCGGACCTTGCCGCGTGGCGGCGCGACATTGCGGCTTTCAATGCGACGAGCCCCATAAT
CCGCAAGGGTCTCGCCACCATGCCCATCAAGTTCGGGGTGTCGTTCAACCTGACCACACTGAACCAGGCCGGCGCGCTGG
TGCACGTCTACACCGACGGCTCGGTGCACTTGAACCACGGCGGCACAGAGATGGGGCAGGGCCTGTTCGTGAAGGTGGCG
CAGGTGGTGGCGGACGCCTTCGGCATTCCCCTCGACCATGTGCGGGTCTCCGCCACCAGCACCGCGAAGGTGCCCAACAC
CTCGCCCACGGCGGCGTCCTCCGGCTCCGACCTCAACGGCATGGCGGCGCTGATCGCGGCGCAGGAGATCCGGGGCCGCA
TGGCAGGTGTGGTCGGCGCCCGTTTCGGGGTGCCGGCGGAGGACGTGGTGTTCGCCGACGGGCGGGTCAGCGCGGGCAAC
CAGAGCCTCTCCTTCGGCGAGGCGGCCAAGCTCGCGTGGCAGGAGCGGGTGCAGCTCTCCGCCGCCGGCTTCTACAAGAC
GCCGAAGATCCATTTCGACCTCGCCACCGCGCAGGGCCGGCCCTTCTATTATTATACCTATGGCGCGGCGGCGGCCGAGG
TGGCGGTGGATACCCTCACCGGCGAGGTGCGGGTGCTGCGGGCCGAGATCGTACAGGATTGCGGCCGCTCCCTGAACCCG
GCCATTGATCTGGGACAGGTGGAAGGCGCCTTCGTTCAGGGCCTCGGCTGGCTCACCTGCGAGGAGCTGAAATGGACCCC
TGAGGGCCGCCTCGCGACCCGTGGCCCCTCCACCTACAAGATCCCCGGCTCCCGCGACGTGCCGCCCGATTTCCGTGTCC
ACCTGCTCGATCGGCCCAACCGGGAAGAGACGGTGCTTCGCTCGAAGGCGGTGGGCGAGCCGCCCCTGATGCTTGCCATC
TCGGTGTGGCTTGCCATCCGCGATGCCATCGCCAGCGTTGCGGGGGAAGGACCCATCCGCCTCGATGCGCCGGCGACGCC
CGAGCGGGTGCTGGAGGCGGTGGCGCTCCGCGGGGGCCATGCCGGGGCCGGATAA

Upstream 100 bases:

>100_bases
GCGCCAGCGCCGCCTATCGCCGGGCGGCGGCGGCCAATCTCGTCCGGCGGCTGCATCTTGCCACCATGCGACCGGACGTG
GCGATCGAGGTCCACGCCCT

Downstream 100 bases:

>100_bases
CCCACGGGCAGGCACGATTCCCGTTGCCTCCTGCGCCCCGCGTCGGATATCTCCCCCAACGCCCCGCGCCACAGGCCGGC
GGGAGGACGCGACGCAAAGG

Product: xanthine dehydrogenase molybdopterin binding subunit

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 764; Mature: 763

Protein sequence:

>764_residues
MSRVVHAPARHESASAHVSGRALYLDDMPEPPGLLHGVLVLSPHPHARIVSIDLSAARALPGVVAVAAGDVPGVNDIAPI
RTGEPALAQGVVEYVGHPVAAVAAPTLDEARSAAALVKIEYEKLPALLDLEEALAAGARVAPDQMVGRGDVDAALAAAPH
RITGEVCCGGQDHFYLEGQIAIAVPGEDRDMQVYSSTQHPTEAQHGVAHVLGLPFAAVTVEVRRMGGAFGGKESQATIIA
AIAALLAHHARKPVKLRLPRDVDMEATGKRHPFRIRWNVGFDSEGRLAGLDLELAADCGNVADLSPAVVSRALCHADNCY
FIPAARYRGLLVKTNTVSNTAFRGFGAPQGMLAIEAVMEAVARHLGLPIEELRAANFYGDAPRNITPYGQEVEDNIIAEV
VAELDGRADLAAWRRDIAAFNATSPIIRKGLATMPIKFGVSFNLTTLNQAGALVHVYTDGSVHLNHGGTEMGQGLFVKVA
QVVADAFGIPLDHVRVSATSTAKVPNTSPTAASSGSDLNGMAALIAAQEIRGRMAGVVGARFGVPAEDVVFADGRVSAGN
QSLSFGEAAKLAWQERVQLSAAGFYKTPKIHFDLATAQGRPFYYYTYGAAAAEVAVDTLTGEVRVLRAEIVQDCGRSLNP
AIDLGQVEGAFVQGLGWLTCEELKWTPEGRLATRGPSTYKIPGSRDVPPDFRVHLLDRPNREETVLRSKAVGEPPLMLAI
SVWLAIRDAIASVAGEGPIRLDAPATPERVLEAVALRGGHAGAG

Sequences:

>Translated_764_residues
MSRVVHAPARHESASAHVSGRALYLDDMPEPPGLLHGVLVLSPHPHARIVSIDLSAARALPGVVAVAAGDVPGVNDIAPI
RTGEPALAQGVVEYVGHPVAAVAAPTLDEARSAAALVKIEYEKLPALLDLEEALAAGARVAPDQMVGRGDVDAALAAAPH
RITGEVCCGGQDHFYLEGQIAIAVPGEDRDMQVYSSTQHPTEAQHGVAHVLGLPFAAVTVEVRRMGGAFGGKESQATIIA
AIAALLAHHARKPVKLRLPRDVDMEATGKRHPFRIRWNVGFDSEGRLAGLDLELAADCGNVADLSPAVVSRALCHADNCY
FIPAARYRGLLVKTNTVSNTAFRGFGAPQGMLAIEAVMEAVARHLGLPIEELRAANFYGDAPRNITPYGQEVEDNIIAEV
VAELDGRADLAAWRRDIAAFNATSPIIRKGLATMPIKFGVSFNLTTLNQAGALVHVYTDGSVHLNHGGTEMGQGLFVKVA
QVVADAFGIPLDHVRVSATSTAKVPNTSPTAASSGSDLNGMAALIAAQEIRGRMAGVVGARFGVPAEDVVFADGRVSAGN
QSLSFGEAAKLAWQERVQLSAAGFYKTPKIHFDLATAQGRPFYYYTYGAAAAEVAVDTLTGEVRVLRAEIVQDCGRSLNP
AIDLGQVEGAFVQGLGWLTCEELKWTPEGRLATRGPSTYKIPGSRDVPPDFRVHLLDRPNREETVLRSKAVGEPPLMLAI
SVWLAIRDAIASVAGEGPIRLDAPATPERVLEAVALRGGHAGAG
>Mature_763_residues
SRVVHAPARHESASAHVSGRALYLDDMPEPPGLLHGVLVLSPHPHARIVSIDLSAARALPGVVAVAAGDVPGVNDIAPIR
TGEPALAQGVVEYVGHPVAAVAAPTLDEARSAAALVKIEYEKLPALLDLEEALAAGARVAPDQMVGRGDVDAALAAAPHR
ITGEVCCGGQDHFYLEGQIAIAVPGEDRDMQVYSSTQHPTEAQHGVAHVLGLPFAAVTVEVRRMGGAFGGKESQATIIAA
IAALLAHHARKPVKLRLPRDVDMEATGKRHPFRIRWNVGFDSEGRLAGLDLELAADCGNVADLSPAVVSRALCHADNCYF
IPAARYRGLLVKTNTVSNTAFRGFGAPQGMLAIEAVMEAVARHLGLPIEELRAANFYGDAPRNITPYGQEVEDNIIAEVV
AELDGRADLAAWRRDIAAFNATSPIIRKGLATMPIKFGVSFNLTTLNQAGALVHVYTDGSVHLNHGGTEMGQGLFVKVAQ
VVADAFGIPLDHVRVSATSTAKVPNTSPTAASSGSDLNGMAALIAAQEIRGRMAGVVGARFGVPAEDVVFADGRVSAGNQ
SLSFGEAAKLAWQERVQLSAAGFYKTPKIHFDLATAQGRPFYYYTYGAAAAEVAVDTLTGEVRVLRAEIVQDCGRSLNPA
IDLGQVEGAFVQGLGWLTCEELKWTPEGRLATRGPSTYKIPGSRDVPPDFRVHLLDRPNREETVLRSKAVGEPPLMLAIS
VWLAIRDAIASVAGEGPIRLDAPATPERVLEAVALRGGHAGAG

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=761, Percent_Identity=44.8094612352168, Blast_Score=624, Evalue=1e-179,
Organism=Homo sapiens, GI71773480, Length=750, Percent_Identity=38.9333333333333, Blast_Score=511, Evalue=1e-144,
Organism=Escherichia coli, GI1789230, Length=777, Percent_Identity=28.8288288288288, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1789246, Length=739, Percent_Identity=27.063599458728, Blast_Score=186, Evalue=6e-48,
Organism=Escherichia coli, GI1786478, Length=735, Percent_Identity=25.9863945578231, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17540638, Length=755, Percent_Identity=37.2185430463576, Blast_Score=496, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17539860, Length=718, Percent_Identity=34.6796657381616, Blast_Score=359, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI32566215, Length=750, Percent_Identity=31.4666666666667, Blast_Score=346, Evalue=2e-95,
Organism=Drosophila melanogaster, GI17737937, Length=755, Percent_Identity=41.8543046357616, Blast_Score=546, Evalue=1e-155,
Organism=Drosophila melanogaster, GI24647199, Length=770, Percent_Identity=30.1298701298701, Blast_Score=311, Evalue=9e-85,
Organism=Drosophila melanogaster, GI24647193, Length=774, Percent_Identity=29.9741602067183, Blast_Score=296, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24647201, Length=767, Percent_Identity=30.8996088657106, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24647195, Length=789, Percent_Identity=29.9112801013942, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24647197, Length=777, Percent_Identity=30.1158301158301, Blast_Score=281, Evalue=9e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 80497; Mature: 80365

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVVHAPARHESASAHVSGRALYLDDMPEPPGLLHGVLVLSPHPHARIVSIDLSAARAL
CCCCCCCCCCCCCCCCEECCEEEEECCCCCCCCCEEEEEEECCCCCCEEEEEEHHHHHCC
PGVVAVAAGDVPGVNDIAPIRTGEPALAQGVVEYVGHPVAAVAAPTLDEARSAAALVKIE
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHCCEEEEEEE
YEKLPALLDLEEALAAGARVAPDQMVGRGDVDAALAAAPHRITGEVCCGGQDHFYLEGQI
HHHCCCCCCHHHHHHCCCCCCHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEEE
AIAVPGEDRDMQVYSSTQHPTEAQHGVAHVLGLPFAAVTVEVRRMGGAFGGKESQATIIA
EEEECCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHH
AIAALLAHHARKPVKLRLPRDVDMEATGKRHPFRIRWNVGFDSEGRLAGLDLELAADCGN
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECEEEEECCCCC
VADLSPAVVSRALCHADNCYFIPAARYRGLLVKTNTVSNTAFRGFGAPQGMLAIEAVMEA
CCCCCHHHHHHHHHCCCCEEEEEHHHHCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
VARHLGLPIEELRAANFYGDAPRNITPYGQEVEDNIIAEVVAELDGRADLAAWRRDIAAF
HHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
NATSPIIRKGLATMPIKFGVSFNLTTLNQAGALVHVYTDGSVHLNHGGTEMGQGLFVKVA
CCCCHHHHCCCHHCCEEECCEEEEEEECCCCCEEEEEECCEEEECCCCCHHCCHHHHHHH
QVVADAFGIPLDHVRVSATSTAKVPNTSPTAASSGSDLNGMAALIAAQEIRGRMAGVVGA
HHHHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RFGVPAEDVVFADGRVSAGNQSLSFGEAAKLAWQERVQLSAAGFYKTPKIHFDLATAQGR
CCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCC
PFYYYTYGAAAAEVAVDTLTGEVRVLRAEIVQDCGRSLNPAIDLGQVEGAFVQGLGWLTC
EEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCEEE
EELKWTPEGRLATRGPSTYKIPGSRDVPPDFRVHLLDRPNREETVLRSKAVGEPPLMLAI
CCCEECCCCCEEECCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHH
SVWLAIRDAIASVAGEGPIRLDAPATPERVLEAVALRGGHAGAG
HHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SRVVHAPARHESASAHVSGRALYLDDMPEPPGLLHGVLVLSPHPHARIVSIDLSAARAL
CCCCCCCCCCCCCCCEECCEEEEECCCCCCCCCEEEEEEECCCCCCEEEEEEHHHHHCC
PGVVAVAAGDVPGVNDIAPIRTGEPALAQGVVEYVGHPVAAVAAPTLDEARSAAALVKIE
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHCCEEEEEEE
YEKLPALLDLEEALAAGARVAPDQMVGRGDVDAALAAAPHRITGEVCCGGQDHFYLEGQI
HHHCCCCCCHHHHHHCCCCCCHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEEE
AIAVPGEDRDMQVYSSTQHPTEAQHGVAHVLGLPFAAVTVEVRRMGGAFGGKESQATIIA
EEEECCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHH
AIAALLAHHARKPVKLRLPRDVDMEATGKRHPFRIRWNVGFDSEGRLAGLDLELAADCGN
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECEEEEECCCCC
VADLSPAVVSRALCHADNCYFIPAARYRGLLVKTNTVSNTAFRGFGAPQGMLAIEAVMEA
CCCCCHHHHHHHHHCCCCEEEEEHHHHCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
VARHLGLPIEELRAANFYGDAPRNITPYGQEVEDNIIAEVVAELDGRADLAAWRRDIAAF
HHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
NATSPIIRKGLATMPIKFGVSFNLTTLNQAGALVHVYTDGSVHLNHGGTEMGQGLFVKVA
CCCCHHHHCCCHHCCEEECCEEEEEEECCCCCEEEEEECCEEEECCCCCHHCCHHHHHHH
QVVADAFGIPLDHVRVSATSTAKVPNTSPTAASSGSDLNGMAALIAAQEIRGRMAGVVGA
HHHHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RFGVPAEDVVFADGRVSAGNQSLSFGEAAKLAWQERVQLSAAGFYKTPKIHFDLATAQGR
CCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCC
PFYYYTYGAAAAEVAVDTLTGEVRVLRAEIVQDCGRSLNPAIDLGQVEGAFVQGLGWLTC
EEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCEEE
EELKWTPEGRLATRGPSTYKIPGSRDVPPDFRVHLLDRPNREETVLRSKAVGEPPLMLAI
CCCEECCCCCEEECCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHH
SVWLAIRDAIASVAGEGPIRLDAPATPERVLEAVALRGGHAGAG
HHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]