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The map label for this gene is tauD [C]

Identifier: 154246709

GI number: 154246709

Start: 3067013

End: 3067984

Strand: Reverse

Name: tauD [C]

Synonym: Xaut_2770

Alternate gene names: 154246709

Gene position: 3067984-3067013 (Counterclockwise)

Preceding gene: 154246713

Following gene: 154246708

Centisome position: 57.79

GC content: 68.11

Gene sequence:

>972_bases
ATGAGCAGCGCGGCTTCCGCCCTCATCACGGATCCGGCATTAAACGTCCCGCCCCGGCACATCGCCATCCATCCGCTCAC
CGGCCAAATTGGCGCGGAGATCGAAGCAGGCGACCTCTCCCGGCCGCTTGCACCCGAGGTGGTGGACGAGATCCGCGCCG
CGCTCCTGAAGTGGAAGGTGGTGTTCTTCCGCGACCAGCCCCTCACCCATGCCCAGCACGTGGCGCTGGCCCGGGCCTTC
GGCGCGCCCACCATCGGCCATCCAGTGTTCGGCTTCGTAGACGGCCATCCCGAGGTCTATTCCATCAGCCGCGACCGCTT
CGCGACGCGCCATGTGGGCGAGCCCCTCATCCGGCCCTGGACCGGATGGCACACGGATGTGACCGCCGCGGTCAATCCAC
CGGCCGCCTCCATCCTGCGCGGCGATGTCATTCCCCCCTACGGCGGCGACACCTTCTGGACCAATCTCGCCGTGGCCTAT
GAGGGCCTGTCGGCGCCGCTGCGCGGCTTCGTTGATACCCTGCGCGGCGTCCATGCCTTCACCGCGCCCGAGGGCCAGGG
CACGACCGAGGACTTCAAAGAGAAGAACAGGCTCCGGCCGCTGGTGAGCGAGCATCCCCTGGTGCGCGTCATCCCCGAGA
CCGGCGAGCGGGTACTGTTCGTCAGCCCGTCCTTCCTCAAGCGCATCACCGGTCTTGCCCCGCGCGAGAGCCAGCAGATC
CTGGACTTGCTGTTCGAGCACATCACCCGGCCGGAATACACGGTGCGGTTCCGCTGGCAGCCCGGCTCCATCGCCTTCTG
GGACAATCGCACCACCGCCCACCTCGCCCCGCGCGACATCTACGCCCTCGACTTCGACCGCCAGCTCTACCGCATCACCC
TCAAGGGCGACGTGCCGGTGGGCGTGGACGGGCGTCCCTCCAGCATCATCGAGGGTGAACCCATCGAGGCGTTCTCCGCC
GGGACGGCCTGA

Upstream 100 bases:

>100_bases
CGTCAATTGATTTAATATAAAATCGATGTATTAAGTTGATTAATAAACCGACGGGTCCCGCCCCCAGCCCGCTCCGGATG
CGCAGGAGAAAGGACAACAC

Downstream 100 bases:

>100_bases
GCACGGCAGGCCGCCTTTCGCCCGCCTTGACGGATCTGCGCCACCGCGCAGGCCCGCCCTCCTGCTGCCGAGCCCCCATC
CATGAGCCGTGACCGCCTGT

Product: taurine dioxygenase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSSAASALITDPALNVPPRHIAIHPLTGQIGAEIEAGDLSRPLAPEVVDEIRAALLKWKVVFFRDQPLTHAQHVALARAF
GAPTIGHPVFGFVDGHPEVYSISRDRFATRHVGEPLIRPWTGWHTDVTAAVNPPAASILRGDVIPPYGGDTFWTNLAVAY
EGLSAPLRGFVDTLRGVHAFTAPEGQGTTEDFKEKNRLRPLVSEHPLVRVIPETGERVLFVSPSFLKRITGLAPRESQQI
LDLLFEHITRPEYTVRFRWQPGSIAFWDNRTTAHLAPRDIYALDFDRQLYRITLKGDVPVGVDGRPSSIIEGEPIEAFSA
GTA

Sequences:

>Translated_323_residues
MSSAASALITDPALNVPPRHIAIHPLTGQIGAEIEAGDLSRPLAPEVVDEIRAALLKWKVVFFRDQPLTHAQHVALARAF
GAPTIGHPVFGFVDGHPEVYSISRDRFATRHVGEPLIRPWTGWHTDVTAAVNPPAASILRGDVIPPYGGDTFWTNLAVAY
EGLSAPLRGFVDTLRGVHAFTAPEGQGTTEDFKEKNRLRPLVSEHPLVRVIPETGERVLFVSPSFLKRITGLAPRESQQI
LDLLFEHITRPEYTVRFRWQPGSIAFWDNRTTAHLAPRDIYALDFDRQLYRITLKGDVPVGVDGRPSSIIEGEPIEAFSA
GTA
>Mature_322_residues
SSAASALITDPALNVPPRHIAIHPLTGQIGAEIEAGDLSRPLAPEVVDEIRAALLKWKVVFFRDQPLTHAQHVALARAFG
APTIGHPVFGFVDGHPEVYSISRDRFATRHVGEPLIRPWTGWHTDVTAAVNPPAASILRGDVIPPYGGDTFWTNLAVAYE
GLSAPLRGFVDTLRGVHAFTAPEGQGTTEDFKEKNRLRPLVSEHPLVRVIPETGERVLFVSPSFLKRITGLAPRESQQIL
DLLFEHITRPEYTVRFRWQPGSIAFWDNRTTAHLAPRDIYALDFDRQLYRITLKGDVPVGVDGRPSSIIEGEPIEAFSAG
TA

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=286, Percent_Identity=40.2097902097902, Blast_Score=187, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6322971, Length=291, Percent_Identity=28.8659793814433, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 35573; Mature: 35442

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAASALITDPALNVPPRHIAIHPLTGQIGAEIEAGDLSRPLAPEVVDEIRAALLKWKV
CCCCCCEEEECCCCCCCCCEEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHEEE
VFFRDQPLTHAQHVALARAFGAPTIGHPVFGFVDGHPEVYSISRDRFATRHVGEPLIRPW
EEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECHHHHHHHHCCCCCCCCC
TGWHTDVTAAVNPPAASILRGDVIPPYGGDTFWTNLAVAYEGLSAPLRGFVDTLRGVHAF
CCCCCEEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEE
TAPEGQGTTEDFKEKNRLRPLVSEHPLVRVIPETGERVLFVSPSFLKRITGLAPRESQQI
ECCCCCCCHHHHHHHHHCCCHHHCCCEEEEECCCCCEEEEECHHHHHHHHCCCCCCHHHH
LDLLFEHITRPEYTVRFRWQPGSIAFWDNRTTAHLAPRDIYALDFDRQLYRITLKGDVPV
HHHHHHHHCCCCEEEEEEECCCCEEEECCCCEEEECCCEEEEEECCCEEEEEEEECCCCC
GVDGRPSSIIEGEPIEAFSAGTA
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSAASALITDPALNVPPRHIAIHPLTGQIGAEIEAGDLSRPLAPEVVDEIRAALLKWKV
CCCCCEEEECCCCCCCCCEEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHEEE
VFFRDQPLTHAQHVALARAFGAPTIGHPVFGFVDGHPEVYSISRDRFATRHVGEPLIRPW
EEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECHHHHHHHHCCCCCCCCC
TGWHTDVTAAVNPPAASILRGDVIPPYGGDTFWTNLAVAYEGLSAPLRGFVDTLRGVHAF
CCCCCEEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEE
TAPEGQGTTEDFKEKNRLRPLVSEHPLVRVIPETGERVLFVSPSFLKRITGLAPRESQQI
ECCCCCCCHHHHHHHHHCCCHHHCCCEEEEECCCCCEEEEECHHHHHHHHCCCCCCHHHH
LDLLFEHITRPEYTVRFRWQPGSIAFWDNRTTAHLAPRDIYALDFDRQLYRITLKGDVPV
HHHHHHHHCCCCEEEEEEECCCCEEEECCCCEEEECCCEEEEEECCCEEEEEEEECCCCC
GVDGRPSSIIEGEPIEAFSAGTA
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]