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The map label for this gene is hrcA

Identifier: 154246475

GI number: 154246475

Start: 2830746

End: 2831846

Strand: Reverse

Name: hrcA

Synonym: Xaut_2534

Alternate gene names: 154246475

Gene position: 2831846-2830746 (Counterclockwise)

Preceding gene: 154246482

Following gene: 154246474

Centisome position: 53.34

GC content: 70.66

Gene sequence:

>1101_bases
GTGGCGCTCGATCCGTTCCAGCCCCTGTCGACCGGCGGCCTCGCGCAGATCGATCAGCGCGCGCGGGAGATCTTCCGCCA
GATCGTGGAAAGCTACCTGGCTACCGGCGAGCCGGTGGGCTCGCGCAATCTCTCGCGCCTTATCCCCATGACCCTGTCGC
CGGCCTCCGTGCGCAACGTGATGGCGGATTTGGAGACGGCGGGCCTCATCTATGCCCCCCACACCAGCGCCGGCCGCCTG
CCCACCGAGCGCGGCCTGCGCTTCTTCGTGGACGCGCTGATGGAAATCGGCGACGTGAACGAGCGCGACCGCACCAATAT
CGAGACCCAGGTGATGGCCGCCGCCAAGACCACCACGGTGGAAGGCGTGCTGCAGGAAGCCTCCGCCATGCTCTCGGGCC
TCGCCCGTGGCGCCGGCGTGGTGACCGCCACCAAGACCGACCCGCGCCTCAAGCATGTGGAGTTCGTGCCGCTGGAGCCG
GGCCGCGCCCTCGTCATCCTCGTCTCCGAGGATGGGCAGGTGGAAAACCGCGTGCTGCCTTTGCCGCCCGGCCTGCCCAC
CTCGGCGCTGACCGAGGCCACCAATTTCCTCAATGCCCGCATCCGCGGCCGCACCCTCGGCGATGCGCGGGCCGAGATGG
AGAACCTGCTCGCCGAGCTGCGGCTCGACCTCGACGCCCTCACCGCGCGGGTGGTGGAGGACGGCCTCGCCTCCTGGTCC
GGCGAGGAGCCGGGCGACCGCAAGCTCATCGTGCGCGGACAAGCCAAGCTGCTGGAGGACCTGCGGGCGCTGGAGGACCT
GGAGCGCATCCGCCTGCTGTTCGACGACCTGGAGACCAAGCGCGAGGTGGTGGACCTGCTGGGCCGCGCCGAGGAGGCGC
AGGCGCTGCGCATCTTCATCGGCTCGGAGAACCGGCTGTTCTCGCTGTCCGGCTCCTCCACCATCGTGGCGCCCTATCGC
GACGGCCAGGGCCGGGTGGTGGGGGTGCTCGGGGTCATCGGCCCGACCCGGCTCAATTACGGGCGCATCGTGCCCATGGT
GGATTTCACCGCCCGGCTGGTCAGCCGCGTGCTCGGCGCGCCCGGCGTGGACGCCGCCTGA

Upstream 100 bases:

>100_bases
AGCCCTTCCCGATGCGCGACGGCGCTTGTGCAGTGCCCCCGTGATGGACACATAATACGTGTCCCGGGGCAGTCCCGGTT
CAGTGGAAAGCGGTGATCCA

Downstream 100 bases:

>100_bases
ACGGATCGCCCGAAAGCCGCGAAACTGTCGGGGGCAGTCCGGCGCCGGTTCTCGCGCAGTCTTGATTTTTCCCGCCGTGG
CCCCGATATCCGCGTTGACA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MALDPFQPLSTGGLAQIDQRAREIFRQIVESYLATGEPVGSRNLSRLIPMTLSPASVRNVMADLETAGLIYAPHTSAGRL
PTERGLRFFVDALMEIGDVNERDRTNIETQVMAAAKTTTVEGVLQEASAMLSGLARGAGVVTATKTDPRLKHVEFVPLEP
GRALVILVSEDGQVENRVLPLPPGLPTSALTEATNFLNARIRGRTLGDARAEMENLLAELRLDLDALTARVVEDGLASWS
GEEPGDRKLIVRGQAKLLEDLRALEDLERIRLLFDDLETKREVVDLLGRAEEAQALRIFIGSENRLFSLSGSSTIVAPYR
DGQGRVVGVLGVIGPTRLNYGRIVPMVDFTARLVSRVLGAPGVDAA

Sequences:

>Translated_366_residues
MALDPFQPLSTGGLAQIDQRAREIFRQIVESYLATGEPVGSRNLSRLIPMTLSPASVRNVMADLETAGLIYAPHTSAGRL
PTERGLRFFVDALMEIGDVNERDRTNIETQVMAAAKTTTVEGVLQEASAMLSGLARGAGVVTATKTDPRLKHVEFVPLEP
GRALVILVSEDGQVENRVLPLPPGLPTSALTEATNFLNARIRGRTLGDARAEMENLLAELRLDLDALTARVVEDGLASWS
GEEPGDRKLIVRGQAKLLEDLRALEDLERIRLLFDDLETKREVVDLLGRAEEAQALRIFIGSENRLFSLSGSSTIVAPYR
DGQGRVVGVLGVIGPTRLNYGRIVPMVDFTARLVSRVLGAPGVDAA
>Mature_365_residues
ALDPFQPLSTGGLAQIDQRAREIFRQIVESYLATGEPVGSRNLSRLIPMTLSPASVRNVMADLETAGLIYAPHTSAGRLP
TERGLRFFVDALMEIGDVNERDRTNIETQVMAAAKTTTVEGVLQEASAMLSGLARGAGVVTATKTDPRLKHVEFVPLEPG
RALVILVSEDGQVENRVLPLPPGLPTSALTEATNFLNARIRGRTLGDARAEMENLLAELRLDLDALTARVVEDGLASWSG
EEPGDRKLIVRGQAKLLEDLRALEDLERIRLLFDDLETKREVVDLLGRAEEAQALRIFIGSENRLFSLSGSSTIVAPYRD
GQGRVVGVLGVIGPTRLNYGRIVPMVDFTARLVSRVLGAPGVDAA

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39621; Mature: 39490

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDPFQPLSTGGLAQIDQRAREIFRQIVESYLATGEPVGSRNLSRLIPMTLSPASVRNV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHH
MADLETAGLIYAPHTSAGRLPTERGLRFFVDALMEIGDVNERDRTNIETQVMAAAKTTTV
HHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
EGVLQEASAMLSGLARGAGVVTATKTDPRLKHVEFVPLEPGRALVILVSEDGQVENRVLP
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEC
LPPGLPTSALTEATNFLNARIRGRTLGDARAEMENLLAELRLDLDALTARVVEDGLASWS
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEEPGDRKLIVRGQAKLLEDLRALEDLERIRLLFDDLETKREVVDLLGRAEEAQALRIFI
CCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
GSENRLFSLSGSSTIVAPYRDGQGRVVGVLGVIGPTRLNYGRIVPMVDFTARLVSRVLGA
CCCCCEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHCC
PGVDAA
CCCCCC
>Mature Secondary Structure 
ALDPFQPLSTGGLAQIDQRAREIFRQIVESYLATGEPVGSRNLSRLIPMTLSPASVRNV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHH
MADLETAGLIYAPHTSAGRLPTERGLRFFVDALMEIGDVNERDRTNIETQVMAAAKTTTV
HHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
EGVLQEASAMLSGLARGAGVVTATKTDPRLKHVEFVPLEPGRALVILVSEDGQVENRVLP
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEC
LPPGLPTSALTEATNFLNARIRGRTLGDARAEMENLLAELRLDLDALTARVVEDGLASWS
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEEPGDRKLIVRGQAKLLEDLRALEDLERIRLLFDDLETKREVVDLLGRAEEAQALRIFI
CCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
GSENRLFSLSGSSTIVAPYRDGQGRVVGVLGVIGPTRLNYGRIVPMVDFTARLVSRVLGA
CCCCCEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHCC
PGVDAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA