Click here to switch to the map view.

The map label for this gene is hmp [H]

Identifier: 154246442

GI number: 154246442

Start: 2795987

End: 2796409

Strand: Reverse

Name: hmp [H]

Synonym: Xaut_2501

Alternate gene names: 154246442

Gene position: 2796409-2795987 (Counterclockwise)

Preceding gene: 154246443

Following gene: 154246441

Centisome position: 52.67

GC content: 69.5

Gene sequence:

>423_bases
ATGACACCGACCCAGATTGACCTGGTCCAGGCCAGCTTCGCCAAGGTGGCGCCCATCGCCGATACGGCGGCGGGCCTGTT
CTACGGCCGCCTGTTCGAGATCGCGCCGGAAGTGAAACCCCTGTTCAAGGGCGACATGACCACCCAGGGCCAGAAGCTGA
TGGCCACCCTCGGCGTGGTGGTCGCCGGCCTGAAGGACCTGCCGCGCATCGTGCCCGCCGCGCAGAACCTCGCCCGCAAG
CATGTGGGCTACGGCGTCAAGACCGAGCACTATGCCCCCGTCGGCGCCGCTCTGCTGTGGACGCTGGAGCAGGGCCTCGG
CGCCGATTTCACCCCCGAGGTGAAGGCCGCCTGGGCCGACGCCTACGGCCTGCTCTCCTCCGTCATGATCGCCGCCGCCG
AAGCCCCCGAGCCGGTGGCCTGA

Upstream 100 bases:

>100_bases
CTCCACGAGCGCCACCGCTACGTGGAAGCCGCCTGAGCCCTTTCGGAGCGGGCCGGCGCGCCCGCTCCCCTCACCTTTTT
TCAAAGCCGGGGATATTGCC

Downstream 100 bases:

>100_bases
GGATCGCGACATGAGCGAGCCCCTCCTCATCATCGGCAACGGCATGGCGGCGGCAAAGCTCTGCGAGGAGCTGAGCCAGC
GCGCGCTCGGCCGCTATGCG

Product: globin

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTPTQIDLVQASFAKVAPIADTAAGLFYGRLFEIAPEVKPLFKGDMTTQGQKLMATLGVVVAGLKDLPRIVPAAQNLARK
HVGYGVKTEHYAPVGAALLWTLEQGLGADFTPEVKAAWADAYGLLSSVMIAAAEAPEPVA

Sequences:

>Translated_140_residues
MTPTQIDLVQASFAKVAPIADTAAGLFYGRLFEIAPEVKPLFKGDMTTQGQKLMATLGVVVAGLKDLPRIVPAAQNLARK
HVGYGVKTEHYAPVGAALLWTLEQGLGADFTPEVKAAWADAYGLLSSVMIAAAEAPEPVA
>Mature_139_residues
TPTQIDLVQASFAKVAPIADTAAGLFYGRLFEIAPEVKPLFKGDMTTQGQKLMATLGVVVAGLKDLPRIVPAAQNLARKH
VGYGVKTEHYAPVGAALLWTLEQGLGADFTPEVKAAWADAYGLLSSVMIAAAEAPEPVA

Specific function: Possesses Dihydropteridine Reductase Activity. Also Has Nitric Oxide Dioxygenase Activity. Seems To Reduces The Complexed Fe(3+) Iron Of Siderophores To Fe(2+), Thus Releasing It From The Chelator. [C]

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI10864065, Length=132, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788903, Length=109, Percent_Identity=35.7798165137615, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR001834
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 14705; Mature: 14574

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTQIDLVQASFAKVAPIADTAAGLFYGRLFEIAPEVKPLFKGDMTTQGQKLMATLGVV
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHH
VAGLKDLPRIVPAAQNLARKHVGYGVKTEHYAPVGAALLWTLEQGLGADFTPEVKAAWAD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
AYGLLSSVMIAAAEAPEPVA
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPTQIDLVQASFAKVAPIADTAAGLFYGRLFEIAPEVKPLFKGDMTTQGQKLMATLGVV
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHH
VAGLKDLPRIVPAAQNLARKHVGYGVKTEHYAPVGAALLWTLEQGLGADFTPEVKAAWAD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
AYGLLSSVMIAAAEAPEPVA
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12835416 [H]