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The map label for this gene is pcp [H]

Identifier: 154246430

GI number: 154246430

Start: 2782230

End: 2782904

Strand: Reverse

Name: pcp [H]

Synonym: Xaut_2489

Alternate gene names: 154246430

Gene position: 2782904-2782230 (Counterclockwise)

Preceding gene: 154246431

Following gene: 154246428

Centisome position: 52.42

GC content: 74.67

Gene sequence:

>675_bases
GTGGCGCACCCGCTCCGCATTCTGGTGACGGCGTTCGGACCGTTCCCGGGGGTGCCGTTGAACCCCTCCCAGCGCACCGC
CAAGGACCTGCTGCGCTTGAAGCGCCCGGCGCTCTGCGGCATGGAAATCACGCTCAGGATCCTGCCCACGCGCTGGGATG
AGCTGCCGCGCCTCGACGCGCTGATGCGGGAGCAGGCGTTCGACGCCGTGCTGTTGCTCGGCGTCGCAGCCCGGCGCCGG
CGTGTCTGCCTTGAGACCCGCGCGGTGAATGCGGCCCGCGCGTTCCCGGATGCCGCCGGCCTGCACCCGCCAGGGCGACG
CCTCTCACGCCGGGGGCTCGATGCCATTGCCTCCACGGCCCCGGCGCTGGCGGGGGTGGCGGCCCTGCAGCGGGCGGGCA
TCGCCGCCTCGGCGTCCCGCGACGCCGGCCGCTATCTGTGCAACGCCGCCTATTTCCACACGCTCGCGGCCGCCCGCGGG
CAGCGGCCGGAAACAGGCGCCGTGCCGCCGGTTCTCTTCGTTCACCTGCCGGGACGCTCGGGCGTTCCGCGCGGCGCCTC
CCGCGCCGGGCTTGCCCGCGCGCTCTCCGGCCTGCTCGTCACACTCGCGGCGGACGCGCGGAGACGGCATTCCAATGCAC
CCGCCCGGAAGGGACAGGGTCTCGACCCCGCCTGA

Upstream 100 bases:

>100_bases
CCGCCTGCCCGCGCTGGAGCAGGAGGTGGCCGCCGGAACGCTCGCCCCGGCGCTGGCGGCGGCGGAGATCGCCGGCCTGA
TCGGGCTGTGAGGGACGGCC

Downstream 100 bases:

>100_bases
GCCCGACCGAGGCCGTCAGGCTCGCTGGATTTCAATCCGGTCGCGACCGCGCTTCTTGGCCCGATACAGGGCCTCATCCG
CATGCCGCATGGCCAAGTCG

Product: peptidase C15 pyroglutamyl peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MAHPLRILVTAFGPFPGVPLNPSQRTAKDLLRLKRPALCGMEITLRILPTRWDELPRLDALMREQAFDAVLLLGVAARRR
RVCLETRAVNAARAFPDAAGLHPPGRRLSRRGLDAIASTAPALAGVAALQRAGIAASASRDAGRYLCNAAYFHTLAAARG
QRPETGAVPPVLFVHLPGRSGVPRGASRAGLARALSGLLVTLAADARRRHSNAPARKGQGLDPA

Sequences:

>Translated_224_residues
MAHPLRILVTAFGPFPGVPLNPSQRTAKDLLRLKRPALCGMEITLRILPTRWDELPRLDALMREQAFDAVLLLGVAARRR
RVCLETRAVNAARAFPDAAGLHPPGRRLSRRGLDAIASTAPALAGVAALQRAGIAASASRDAGRYLCNAAYFHTLAAARG
QRPETGAVPPVLFVHLPGRSGVPRGASRAGLARALSGLLVTLAADARRRHSNAPARKGQGLDPA
>Mature_223_residues
AHPLRILVTAFGPFPGVPLNPSQRTAKDLLRLKRPALCGMEITLRILPTRWDELPRLDALMREQAFDAVLLLGVAARRRR
VCLETRAVNAARAFPDAAGLHPPGRRLSRRGLDAIASTAPALAGVAALQRAGIAASASRDAGRYLCNAAYFHTLAAARGQ
RPETGAVPPVLFVHLPGRSGVPRGASRAGLARALSGLLVTLAADARRRHSNAPARKGQGLDPA

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 23750; Mature: 23619

Theoretical pI: Translated: 12.25; Mature: 12.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHPLRILVTAFGPFPGVPLNPSQRTAKDLLRLKRPALCGMEITLRILPTRWDELPRLDA
CCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHH
LMREQAFDAVLLLGVAARRRRVCLETRAVNAARAFPDAAGLHPPGRRLSRRGLDAIASTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
PALAGVAALQRAGIAASASRDAGRYLCNAAYFHTLAAARGQRPETGAVPPVLFVHLPGRS
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCC
GVPRGASRAGLARALSGLLVTLAADARRRHSNAPARKGQGLDPA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AHPLRILVTAFGPFPGVPLNPSQRTAKDLLRLKRPALCGMEITLRILPTRWDELPRLDA
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHH
LMREQAFDAVLLLGVAARRRRVCLETRAVNAARAFPDAAGLHPPGRRLSRRGLDAIASTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
PALAGVAALQRAGIAASASRDAGRYLCNAAYFHTLAAARGQRPETGAVPPVLFVHLPGRS
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCC
GVPRGASRAGLARALSGLLVTLAADARRRHSNAPARKGQGLDPA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA