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The map label for this gene is actP

Identifier: 154246372

GI number: 154246372

Start: 2717933

End: 2719666

Strand: Reverse

Name: actP

Synonym: Xaut_2431

Alternate gene names: 154246372

Gene position: 2719666-2717933 (Counterclockwise)

Preceding gene: 154246373

Following gene: 154246371

Centisome position: 51.23

GC content: 67.24

Gene sequence:

>1734_bases
ATGTCGACGCATGCTTTCATCGGCAAGGCGGCGCGCCTTGCGGGCCTCGCCGCCCTTGCGCTTGTCCCCACGGCGGCCTT
CGCGGCCGAGGCCATCGGCGCCTCGGAGAAGCAGGCCACCAACTGGACCGCGATCGCCATGTTCGCGATCTTCGTGGTCG
GCACCCTCTTCATCACCAAGTGGGCGGCCTCGAAGACCAAGTCGGCGGCCGACTTCTACACCGCCGGCGGCGGCATCACC
GGCTTCCAGAACGGCCTCGCCATCGCCGGTGACTACATGTCCGCGGCCTCGTTCCTCGGCATCTCCGCGGCGGTGATGAG
CTCCGGCTTCGACGGCCTCATCTACTCCATCGGCTTCCTTGTCGGCTGGCCCATCCTCACCTTCCTGATGGCGGAGCGCC
TGCGCAACCTCGGCAAGTTCACCTTCGCCGACGTGGCCGCCTTCCGCTTCGCCCAGACCCCCGTGCGCGTGTTCGCGGCG
TCCGGCACGCTGGTGGTGGTGGCCTTCTATCTCATCGCCCAGATGGTGGGCGCCGGCCAGCTGATCAAGCTGCTGTTCGG
CCTCGACTACTGGATCGCGGTGGTGATCGTCGGCGCGCTGATGATGGTCTACGTGCTGTTCGGCGGCATGACCGCCACCA
CCTGGGTGCAGATCATCAAGGCCTGCCTGCTGCTCGGCGGCGCCACCTTCATGGCCATCATGGTCATGTGGCGCTACGGC
TTCAGCCCGGAGAACCTGTTCGCGGCGGCGGTTGGCATCAAGACGCAGCTTGCGGCGGCCAAGCCCGGCATCACCCCCGA
GGCGGCGGCCGCGGCCGGCCAGTCCATCATGGGGCCGGGCACCTTCATCAAGGACCCGATCTCGGCCATCTCCTTCGGCA
TGGCGCTGATGTTCGGCACCGCCGGCCTGCCCCATATCCTGATGCGCTTCTTCACCGTGCCGAGCGCCAAGGAAGCGCGC
AAGTCAGTGATGTGGGCCACCGGGTGGATCGGCTACTTCTACCTGCTCACCTTCATCATCGGCTTCGGCGCCATCACCTT
CGTGCTGACCAATCCGGAATTCCTGGATGCCAAGGGCGGCCTCGTGGGCGGCTCCAACATGGCGGCGGTGCACCTGGCCC
GCGCGGTCGGCGGCAACATCTTCCTCGGCTTCATCTCGGCGGTGGCGTTCGCGACCATCCTCGCGGTGGTGGCCGGCCTG
ACGCTCTCGGGCGCCTCGGCGGTGTCGCACGACCTCTATTCGACCGTGATCAAGAAGGGCAAGGCCGACAGCGCCTCGGA
GCTGAAGGTCTCGCGCGTCACCACCATCTGCCTCGGCATCCTGGCGGTGCTGCTGGGCATCGCCTTCGAGAAGCAGAACA
TCGCCTTCATGGTGTCCCTGGCCTTCGCGGTGGCGGCCTCGGCCAACTTCCCGGTGCTGTTCATGTCGGTGCTGTGGAAG
GACTGCACCACCAAGGGCGCCGTGGTCGGCGGCTTCCTGGGCCTTGCGGCCTCGGTGATCCTGACCATCCTGTCGCCCTC
GGTGTGGGAAGCGACCCTGGGCAACCCGGCCGGTTCCGCGCCGTTCCCCTACACCTCGCCGGCGCTGTTCTCCATGACGC
TGGGCTTCATCGGCATCTGGCTGGTCTCGATCCTCGACAACAGCCAGCGGGCGAAGATCGACCGGGCAGGCTTCCCGGCG
CAGCAGGTGCGCTCCGAAACCGGCATCGGGGCGTCGGAAGCCTCGGGTCACTGA

Upstream 100 bases:

>100_bases
TGATCGTCTTCACGATCCTCATCACCGCCGTCTACGTCCGCCGCGCGAACAGCGAGTTCGACGACCTTTCCGAGAAGATC
AAGCAGCAGGTGCTCAAGTG

Downstream 100 bases:

>100_bases
CCTAAAGGCCCTCCCGATGCCGCGGCCGGATCATCCTCCGCCCGGCACCGCAGATGAGGACAGCCGGACCAGCACCCCCC
GGGCCGACACGGCCCGGGGA

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 577; Mature: 576

Protein sequence:

>577_residues
MSTHAFIGKAARLAGLAALALVPTAAFAAEAIGASEKQATNWTAIAMFAIFVVGTLFITKWAASKTKSAADFYTAGGGIT
GFQNGLAIAGDYMSAASFLGISAAVMSSGFDGLIYSIGFLVGWPILTFLMAERLRNLGKFTFADVAAFRFAQTPVRVFAA
SGTLVVVAFYLIAQMVGAGQLIKLLFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACLLLGGATFMAIMVMWRYG
FSPENLFAAAVGIKTQLAAAKPGITPEAAAAAGQSIMGPGTFIKDPISAISFGMALMFGTAGLPHILMRFFTVPSAKEAR
KSVMWATGWIGYFYLLTFIIGFGAITFVLTNPEFLDAKGGLVGGSNMAAVHLARAVGGNIFLGFISAVAFATILAVVAGL
TLSGASAVSHDLYSTVIKKGKADSASELKVSRVTTICLGILAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFMSVLWK
DCTTKGAVVGGFLGLAASVILTILSPSVWEATLGNPAGSAPFPYTSPALFSMTLGFIGIWLVSILDNSQRAKIDRAGFPA
QQVRSETGIGASEASGH

Sequences:

>Translated_577_residues
MSTHAFIGKAARLAGLAALALVPTAAFAAEAIGASEKQATNWTAIAMFAIFVVGTLFITKWAASKTKSAADFYTAGGGIT
GFQNGLAIAGDYMSAASFLGISAAVMSSGFDGLIYSIGFLVGWPILTFLMAERLRNLGKFTFADVAAFRFAQTPVRVFAA
SGTLVVVAFYLIAQMVGAGQLIKLLFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACLLLGGATFMAIMVMWRYG
FSPENLFAAAVGIKTQLAAAKPGITPEAAAAAGQSIMGPGTFIKDPISAISFGMALMFGTAGLPHILMRFFTVPSAKEAR
KSVMWATGWIGYFYLLTFIIGFGAITFVLTNPEFLDAKGGLVGGSNMAAVHLARAVGGNIFLGFISAVAFATILAVVAGL
TLSGASAVSHDLYSTVIKKGKADSASELKVSRVTTICLGILAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFMSVLWK
DCTTKGAVVGGFLGLAASVILTILSPSVWEATLGNPAGSAPFPYTSPALFSMTLGFIGIWLVSILDNSQRAKIDRAGFPA
QQVRSETGIGASEASGH
>Mature_576_residues
STHAFIGKAARLAGLAALALVPTAAFAAEAIGASEKQATNWTAIAMFAIFVVGTLFITKWAASKTKSAADFYTAGGGITG
FQNGLAIAGDYMSAASFLGISAAVMSSGFDGLIYSIGFLVGWPILTFLMAERLRNLGKFTFADVAAFRFAQTPVRVFAAS
GTLVVVAFYLIAQMVGAGQLIKLLFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACLLLGGATFMAIMVMWRYGF
SPENLFAAAVGIKTQLAAAKPGITPEAAAAAGQSIMGPGTFIKDPISAISFGMALMFGTAGLPHILMRFFTVPSAKEARK
SVMWATGWIGYFYLLTFIIGFGAITFVLTNPEFLDAKGGLVGGSNMAAVHLARAVGGNIFLGFISAVAFATILAVVAGLT
LSGASAVSHDLYSTVIKKGKADSASELKVSRVTTICLGILAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFMSVLWKD
CTTKGAVVGGFLGLAASVILTILSPSVWEATLGNPAGSAPFPYTSPALFSMTLGFIGIWLVSILDNSQRAKIDRAGFPAQ
QVRSETGIGASEASGH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=484, Percent_Identity=22.5206611570248, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI1790503, Length=559, Percent_Identity=64.0429338103757, Blast_Score=699, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=454, Percent_Identity=23.3480176211454, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 60033; Mature: 59902

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHAFIGKAARLAGLAALALVPTAAFAAEAIGASEKQATNWTAIAMFAIFVVGTLFITK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
WAASKTKSAADFYTAGGGITGFQNGLAIAGDYMSAASFLGISAAVMSSGFDGLIYSIGFL
HHHHCCCCHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VGWPILTFLMAERLRNLGKFTFADVAAFRFAQTPVRVFAASGTLVVVAFYLIAQMVGAGQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHEECCCHHHHHHHHHHHHHHCHHH
LIKLLFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACLLLGGATFMAIMVMWRYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
FSPENLFAAAVGIKTQLAAAKPGITPEAAAAAGQSIMGPGTFIKDPISAISFGMALMFGT
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
AGLPHILMRFFTVPSAKEARKSVMWATGWIGYFYLLTFIIGFGAITFVLTNPEFLDAKGG
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
LVGGSNMAAVHLARAVGGNIFLGFISAVAFATILAVVAGLTLSGASAVSHDLYSTVIKKG
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
KADSASELKVSRVTTICLGILAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFMSVLWK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
DCTTKGAVVGGFLGLAASVILTILSPSVWEATLGNPAGSAPFPYTSPALFSMTLGFIGIW
HHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LVSILDNSQRAKIDRAGFPAQQVRSETGIGASEASGH
HHHHHCCCHHHCCCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
STHAFIGKAARLAGLAALALVPTAAFAAEAIGASEKQATNWTAIAMFAIFVVGTLFITK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
WAASKTKSAADFYTAGGGITGFQNGLAIAGDYMSAASFLGISAAVMSSGFDGLIYSIGFL
HHHHCCCCHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VGWPILTFLMAERLRNLGKFTFADVAAFRFAQTPVRVFAASGTLVVVAFYLIAQMVGAGQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHEECCCHHHHHHHHHHHHHHCHHH
LIKLLFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACLLLGGATFMAIMVMWRYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
FSPENLFAAAVGIKTQLAAAKPGITPEAAAAAGQSIMGPGTFIKDPISAISFGMALMFGT
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
AGLPHILMRFFTVPSAKEARKSVMWATGWIGYFYLLTFIIGFGAITFVLTNPEFLDAKGG
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
LVGGSNMAAVHLARAVGGNIFLGFISAVAFATILAVVAGLTLSGASAVSHDLYSTVIKKG
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
KADSASELKVSRVTTICLGILAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFMSVLWK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
DCTTKGAVVGGFLGLAASVILTILSPSVWEATLGNPAGSAPFPYTSPALFSMTLGFIGIW
HHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LVSILDNSQRAKIDRAGFPAQQVRSETGIGASEASGH
HHHHHCCCHHHCCCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA