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The map label for this gene is thrB

Identifier: 154246298

GI number: 154246298

Start: 2629775

End: 2630740

Strand: Direct

Name: thrB

Synonym: Xaut_2356

Alternate gene names: 154246298

Gene position: 2629775-2630740 (Clockwise)

Preceding gene: 154246297

Following gene: 154246299

Centisome position: 49.53

GC content: 68.53

Gene sequence:

>966_bases
GTGGCGGTCTATACGGACGTTGCGCCGGCGGAGCTTGAGGCTTTCCTGTCCGGCTACGACATCGGCACGCTCACCTCTTT
CCACGGCATCGCGGAAGGGGTGGAGAACTCCAACTTCCTGGTTCAGACCACGCGCGGCAGCTACATCCTCACCCTCTATG
AGAAGCGGGTGAACCGGGACGATTTGCCCTTCTTCATCGGCCTCATGGAGCATCTGGCGGCGCGTGGCCTGTCGTGCCCG
CAGCCGGTGGCGCAGCGCTCGGGGGCGGTGCTGTCGGAGATCGCGGGGCGGCCGGCGGCCATGGTCACCTTCCTGCCCGG
CGTCTCGGTGCGGCGGCCCACGGCCGAGCATTGCGCCGAGCTGGGGCGGGGCCTCGCCCAGCTGCATCTGGCCGGCGCTG
ACTTCGCCATGAGGCGGGCCAACAACCTCTCCGTCGCCGGCTGGCGGCCTTTGTTCGTGGCGGCGGACGGGCAGGCCGAC
GACGTGGCGCCGGGCCTTGCCGATGCCATCGCGGCGGAGCTGGCAACGCTGGAGGCGAACTGGCCGCAGGGTCTGCCGGC
GGGCGTCATTCATGCCGACCTGTTCCCGGACAACGCCTTCTTCCTCGATGAAAAGCTCTCGGGCATCATCGACTTCTACT
TCGCCTGCACCGACTTCCTCGCCTATGACGTGGCGGTGTGCCTCAACGCCTGGTGCTTCGAGCCGGACGGCTCCTACAAC
GTCACCAAGGGGCGGGCGCTGCTGTCGGGCTATGAAGCGGTGCGGCCCCTGTCGGGGGCCGAGAAGGCAGCCCTGCCGCG
CCTTGCCCGGGGCGCTGCCCTGCGCTTCCTGCTCACCCGCCTCGTGGACTGGCTGAACGTGCCCGAGGGCGCTTTGGTGC
GCCCCAAGGACCCGCTGGAATATCTGAAGAAGCTGCGCTTCCACCAGGCGGTGGACAGCGCGCAGGATTACGGTCTGGCG
GCATGA

Upstream 100 bases:

>100_bases
CGAACGCTTCACCGTGACGGTCGAGACTGTGACCTCAACGGAGGAGGACGTGTTCTTCCCCCTGCCGCGCGCCCTGCGGC
CGGATGCGGCGGAGTAGAAC

Downstream 100 bases:

>100_bases
AAGAAGTGGCGGTGTTCACGGACGGGGCCTGCTCGGGCAATCCCGGCCCCGGCGGCTGGGGCGCGATCCTGCGCTTCGGC
GCCCACGAGAAGGAGCTGAG

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAVYTDVAPAELEAFLSGYDIGTLTSFHGIAEGVENSNFLVQTTRGSYILTLYEKRVNRDDLPFFIGLMEHLAARGLSCP
QPVAQRSGAVLSEIAGRPAAMVTFLPGVSVRRPTAEHCAELGRGLAQLHLAGADFAMRRANNLSVAGWRPLFVAADGQAD
DVAPGLADAIAAELATLEANWPQGLPAGVIHADLFPDNAFFLDEKLSGIIDFYFACTDFLAYDVAVCLNAWCFEPDGSYN
VTKGRALLSGYEAVRPLSGAEKAALPRLARGAALRFLLTRLVDWLNVPEGALVRPKDPLEYLKKLRFHQAVDSAQDYGLA
A

Sequences:

>Translated_321_residues
MAVYTDVAPAELEAFLSGYDIGTLTSFHGIAEGVENSNFLVQTTRGSYILTLYEKRVNRDDLPFFIGLMEHLAARGLSCP
QPVAQRSGAVLSEIAGRPAAMVTFLPGVSVRRPTAEHCAELGRGLAQLHLAGADFAMRRANNLSVAGWRPLFVAADGQAD
DVAPGLADAIAAELATLEANWPQGLPAGVIHADLFPDNAFFLDEKLSGIIDFYFACTDFLAYDVAVCLNAWCFEPDGSYN
VTKGRALLSGYEAVRPLSGAEKAALPRLARGAALRFLLTRLVDWLNVPEGALVRPKDPLEYLKKLRFHQAVDSAQDYGLA
A
>Mature_320_residues
AVYTDVAPAELEAFLSGYDIGTLTSFHGIAEGVENSNFLVQTTRGSYILTLYEKRVNRDDLPFFIGLMEHLAARGLSCPQ
PVAQRSGAVLSEIAGRPAAMVTFLPGVSVRRPTAEHCAELGRGLAQLHLAGADFAMRRANNLSVAGWRPLFVAADGQADD
VAPGLADAIAAELATLEANWPQGLPAGVIHADLFPDNAFFLDEKLSGIIDFYFACTDFLAYDVAVCLNAWCFEPDGSYNV
TKGRALLSGYEAVRPLSGAEKAALPRLARGAALRFLLTRLVDWLNVPEGALVRPKDPLEYLKKLRFHQAVDSAQDYGLAA

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_XANP2 (A7IHV6)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001417256.1
- ProteinModelPortal:   A7IHV6
- SMR:   A7IHV6
- STRING:   A7IHV6
- GeneID:   5422658
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2356
- eggNOG:   COG2334
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- BioCyc:   XAUT78245:XAUT_2356-MONOMER
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 34614; Mature: 34483

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTDVAPAELEAFLSGYDIGTLTSFHGIAEGVENSNFLVQTTRGSYILTLYEKRVNRD
CCEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHCCCC
DLPFFIGLMEHLAARGLSCPQPVAQRSGAVLSEIAGRPAAMVTFLPGVSVRRPTAEHCAE
CCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHH
LGRGLAQLHLAGADFAMRRANNLSVAGWRPLFVAADGQADDVAPGLADAIAAELATLEAN
HHHHHHHHHHCCCHHHHHHCCCCCEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCC
WPQGLPAGVIHADLFPDNAFFLDEKLSGIIDFYFACTDFLAYDVAVCLNAWCFEPDGSYN
CCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
VTKGRALLSGYEAVRPLSGAEKAALPRLARGAALRFLLTRLVDWLNVPEGALVRPKDPLE
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHH
YLKKLRFHQAVDSAQDYGLAA
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AVYTDVAPAELEAFLSGYDIGTLTSFHGIAEGVENSNFLVQTTRGSYILTLYEKRVNRD
CEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHCCCC
DLPFFIGLMEHLAARGLSCPQPVAQRSGAVLSEIAGRPAAMVTFLPGVSVRRPTAEHCAE
CCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHH
LGRGLAQLHLAGADFAMRRANNLSVAGWRPLFVAADGQADDVAPGLADAIAAELATLEAN
HHHHHHHHHHCCCHHHHHHCCCCCEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCC
WPQGLPAGVIHADLFPDNAFFLDEKLSGIIDFYFACTDFLAYDVAVCLNAWCFEPDGSYN
CCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
VTKGRALLSGYEAVRPLSGAEKAALPRLARGAALRFLLTRLVDWLNVPEGALVRPKDPLE
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHH
YLKKLRFHQAVDSAQDYGLAA
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA