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The map label for this gene is tctD [H]

Identifier: 154246206

GI number: 154246206

Start: 2523877

End: 2524542

Strand: Reverse

Name: tctD [H]

Synonym: Xaut_2264

Alternate gene names: 154246206

Gene position: 2524542-2523877 (Counterclockwise)

Preceding gene: 154246208

Following gene: 154246205

Centisome position: 47.55

GC content: 65.32

Gene sequence:

>666_bases
ATGCGTATCCTCATCGTGGAAGACGACCGGTCTCTGGCAAGCGGGCTGAAGCGCTCGCTTACCTCGCTCGGCTATGCGGT
CGACCATGAGGCTGATGTGGCCGATGCGGTCGGGTTGGCGACCCGCGAGGCGTACAATCTGGTCGTGCTCGATCTCGGCC
TTCCCAACGGAAGCGGATATGACGTGCTGCGGGCGATCCGCCGCAATGGCCTTAAGACGCCGGTCATGATCCTCACAGCC
CGCGACCATGTGAGCGAGAAGGTGAAGGCGCTGGACCTCGGCGCTGACGATTATGTGCATAAGCCCTTTGCCCTCGCCGA
GTTCGAGGCGCGGGTGCGTGCGCTGGTGCGCCGGGGCTTTGGCGTCAGCGACGTCGTTCTCGAATTCGGGCCGCTGCAGT
TCGATACGGCGCAGCAAGTCGCGCGGCTGGAGGGCTCCCCCCTTGATCTGAGGCGGCGGGAGCTGGCGGTTCTGCATCTT
CTCCTGCTTCAGGCGGGCAAGCTTGTACCCAAGGCACGCCTCATCTCGGAGGTGTTCGGATTGGATGACGCGGTAGGCCC
GAACGCCCTGGAGCTGTACATCGCCCGCCTGCGCAAGAAGCTCGGGGCCGGAGGGCTGCGCATCCGCACCGTCCGCGGGC
TCGGCTACATGCTGGAGAGGGGCTGA

Upstream 100 bases:

>100_bases
CCTGATCAAGTAGCAGGTGGTGCGCATCGACCGCCCGGAATTCTGTGCGCGGGCGGGTTTCCGGCCGCCCGTCCGACAAT
TGGCGGGAGAATATGTGTTG

Downstream 100 bases:

>100_bases
TGCGCGACGCCCGCCGCTCGCTGAAGCGCGCGGTTCTCCTCAATCTGCTCGCGCCGGTACTGCTGCTGGCTGTAGCTATC
GGAGCCGGCGGCTACCTCAC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRILIVEDDRSLASGLKRSLTSLGYAVDHEADVADAVGLATREAYNLVVLDLGLPNGSGYDVLRAIRRNGLKTPVMILTA
RDHVSEKVKALDLGADDYVHKPFALAEFEARVRALVRRGFGVSDVVLEFGPLQFDTAQQVARLEGSPLDLRRRELAVLHL
LLLQAGKLVPKARLISEVFGLDDAVGPNALELYIARLRKKLGAGGLRIRTVRGLGYMLERG

Sequences:

>Translated_221_residues
MRILIVEDDRSLASGLKRSLTSLGYAVDHEADVADAVGLATREAYNLVVLDLGLPNGSGYDVLRAIRRNGLKTPVMILTA
RDHVSEKVKALDLGADDYVHKPFALAEFEARVRALVRRGFGVSDVVLEFGPLQFDTAQQVARLEGSPLDLRRRELAVLHL
LLLQAGKLVPKARLISEVFGLDDAVGPNALELYIARLRKKLGAGGLRIRTVRGLGYMLERG
>Mature_221_residues
MRILIVEDDRSLASGLKRSLTSLGYAVDHEADVADAVGLATREAYNLVVLDLGLPNGSGYDVLRAIRRNGLKTPVMILTA
RDHVSEKVKALDLGADDYVHKPFALAEFEARVRALVRRGFGVSDVVLEFGPLQFDTAQQVARLEGSPLDLRRRELAVLHL
LLLQAGKLVPKARLISEVFGLDDAVGPNALELYIARLRKKLGAGGLRIRTVRGLGYMLERG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=41.2844036697248, Blast_Score=164, Evalue=3e-42,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=43.1192660550459, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=34.8623853211009, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=35.5855855855856, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.4841628959276, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=31.3636363636364, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=31.2775330396476, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=33.9130434782609, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=31.981981981982, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=30.4932735426009, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.3185840707965, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=28, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=28.755364806867, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=35.6435643564356, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24176; Mature: 24176

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIVEDDRSLASGLKRSLTSLGYAVDHEADVADAVGLATREAYNLVVLDLGLPNGSGY
CEEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCCH
DVLRAIRRNGLKTPVMILTARDHVSEKVKALDLGADDYVHKPFALAEFEARVRALVRRGF
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHCC
GVSDVVLEFGPLQFDTAQQVARLEGSPLDLRRRELAVLHLLLLQAGKLVPKARLISEVFG
CHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
LDDAVGPNALELYIARLRKKLGAGGLRIRTVRGLGYMLERG
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHCCC
>Mature Secondary Structure
MRILIVEDDRSLASGLKRSLTSLGYAVDHEADVADAVGLATREAYNLVVLDLGLPNGSGY
CEEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCCH
DVLRAIRRNGLKTPVMILTARDHVSEKVKALDLGADDYVHKPFALAEFEARVRALVRRGF
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHCC
GVSDVVLEFGPLQFDTAQQVARLEGSPLDLRRRELAVLHLLLLQAGKLVPKARLISEVFG
CHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
LDDAVGPNALELYIARLRKKLGAGGLRIRTVRGLGYMLERG
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]