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The map label for this gene is qseC [H]

Identifier: 154246205

GI number: 154246205

Start: 2522444

End: 2523877

Strand: Reverse

Name: qseC [H]

Synonym: Xaut_2263

Alternate gene names: 154246205

Gene position: 2523877-2522444 (Counterclockwise)

Preceding gene: 154246206

Following gene: 154246203

Centisome position: 47.54

GC content: 67.99

Gene sequence:

>1434_bases
ATGCGCGACGCCCGCCGCTCGCTGAAGCGCGCGGTTCTCCTCAATCTGCTCGCGCCGGTACTGCTGCTGGCTGTAGCTAT
CGGAGCCGGCGGCTACCTCACGATCACGTCGGTGGTGGAGAGTTCCCATGATCGCCTCCTCGACGGCTCGCTGATGGCCA
TCGCCGAGCGCCTCGCGGTGGAGAGCGGAGAGGTTGTGGTGGACATGCCGCAAGTCGCGTTGGGCATGCTCGAAACCAAG
ACGCAGGACAACGTTTATTATCTCGTCGCCTCCGACTCCGGGCCGGTGACGGGCTATCCCGACCTGCCCCTCGGAAAGAT
GGCGGCCGCGGAGCCCGGCCAGCCGACCCACTGGGACGGCACCTATCGCGGCAATGCGGTGCGGCTCGCCGCGGTGGCAC
GCCGTGTCTATGGCGTCGAACGCCCGGTCATCGTCGCCGTCGCCGAGACCCGGCTCGCCCGCAATCAGCTGCGCAACGAA
ATGCTGCGGAACCTTGGCGTTGCTGAGGCCGCCCTGATCCTGGCCATCGCCGTGCTGGCGTGGGTGTCCGTCGAGCGCGG
GCTGATGCCTCTCGCCGATCTCAGCCGGCAAATCGACACCCGCGCCGTCAGCGACTGGCGCGACCTGCGGCCGCTCGATC
TGTCCGGCGTGCCGCAGGAGGCGATGGCGCCCGCCACCGCTATCAATGCCATGTTCGAGCGCCTGCGCTCGGCGACGGCG
CTTCTGCGGCGCTTCACGGCCGATGCCTCCCACCAGATGCGCACGCCGCTGGCGATCGTGAGGATGCATGTGGATCTGCT
GCGACGGGAGAGCTCCGATCCCGAGCTGCGCAGCAGTGTCCTGGCCGAGCTGGATCAGGGGGCGGAGCGGCTGGAGCGGC
TCATCACCCAGCTCCTCACCCTCGCCCGTGCCGACGAAAGCGCCGTCGCGGCAGCGGGCGGCACGCCCTGCGATCTGGGC
GAGGTGATCGAGTATGTCATCGCCGAGCGCATCGCCGGCATCCCACCCGACACCCAGATCTCCTGCCTCATCAGGCATCG
CCCCTTGCCGCTGATTTCCGACACCGTTCTGCTGTCCGAACTGCTGGGCAATCTTCTGGACAATGCAGTGAAATATTCCG
GCGCGGGCGGTCAGGTGGTGCTGTGCGCCGAGCGGGACGGGCACTTGGCGCTTGTGACCATCGAGGACAGCGGTCCGGGC
ATTCCGGAAGCCGAGCGGGAGCAGGTGTTCCGGCGCTTCTATCGCGCGCCCGACCGGCCGGACGTACCCGGCAGCGGTCT
CGGGCTTTCGATCGTGAAGGTGATCGCGGACCTGCTGCACATTTCAATCGTCCTCGACCGCAGCCCTGACCTCGGCGGCC
TGCGGGTCACCCTGCGCATGACGCTGTCTCCTTTGCTCTACCATGAGGCGGCAGGAGCTGCGGCGCGGGGCTAG

Upstream 100 bases:

>100_bases
CCCTGGAGCTGTACATCGCCCGCCTGCGCAAGAAGCTCGGGGCCGGAGGGCTGCGCATCCGCACCGTCCGCGGGCTCGGC
TACATGCTGGAGAGGGGCTG

Downstream 100 bases:

>100_bases
ACGCCGGTTCGGCGCACAGCCCCCTCCTCAGATAGCGATGCTACCGTTCTCGGTTAAATGAGGCGGTTGAAACGAACTTG
CAATAAACCGACCCTCCGAG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MRDARRSLKRAVLLNLLAPVLLLAVAIGAGGYLTITSVVESSHDRLLDGSLMAIAERLAVESGEVVVDMPQVALGMLETK
TQDNVYYLVASDSGPVTGYPDLPLGKMAAAEPGQPTHWDGTYRGNAVRLAAVARRVYGVERPVIVAVAETRLARNQLRNE
MLRNLGVAEAALILAIAVLAWVSVERGLMPLADLSRQIDTRAVSDWRDLRPLDLSGVPQEAMAPATAINAMFERLRSATA
LLRRFTADASHQMRTPLAIVRMHVDLLRRESSDPELRSSVLAELDQGAERLERLITQLLTLARADESAVAAAGGTPCDLG
EVIEYVIAERIAGIPPDTQISCLIRHRPLPLISDTVLLSELLGNLLDNAVKYSGAGGQVVLCAERDGHLALVTIEDSGPG
IPEAEREQVFRRFYRAPDRPDVPGSGLGLSIVKVIADLLHISIVLDRSPDLGGLRVTLRMTLSPLLYHEAAGAAARG

Sequences:

>Translated_477_residues
MRDARRSLKRAVLLNLLAPVLLLAVAIGAGGYLTITSVVESSHDRLLDGSLMAIAERLAVESGEVVVDMPQVALGMLETK
TQDNVYYLVASDSGPVTGYPDLPLGKMAAAEPGQPTHWDGTYRGNAVRLAAVARRVYGVERPVIVAVAETRLARNQLRNE
MLRNLGVAEAALILAIAVLAWVSVERGLMPLADLSRQIDTRAVSDWRDLRPLDLSGVPQEAMAPATAINAMFERLRSATA
LLRRFTADASHQMRTPLAIVRMHVDLLRRESSDPELRSSVLAELDQGAERLERLITQLLTLARADESAVAAAGGTPCDLG
EVIEYVIAERIAGIPPDTQISCLIRHRPLPLISDTVLLSELLGNLLDNAVKYSGAGGQVVLCAERDGHLALVTIEDSGPG
IPEAEREQVFRRFYRAPDRPDVPGSGLGLSIVKVIADLLHISIVLDRSPDLGGLRVTLRMTLSPLLYHEAAGAAARG
>Mature_477_residues
MRDARRSLKRAVLLNLLAPVLLLAVAIGAGGYLTITSVVESSHDRLLDGSLMAIAERLAVESGEVVVDMPQVALGMLETK
TQDNVYYLVASDSGPVTGYPDLPLGKMAAAEPGQPTHWDGTYRGNAVRLAAVARRVYGVERPVIVAVAETRLARNQLRNE
MLRNLGVAEAALILAIAVLAWVSVERGLMPLADLSRQIDTRAVSDWRDLRPLDLSGVPQEAMAPATAINAMFERLRSATA
LLRRFTADASHQMRTPLAIVRMHVDLLRRESSDPELRSSVLAELDQGAERLERLITQLLTLARADESAVAAAGGTPCDLG
EVIEYVIAERIAGIPPDTQISCLIRHRPLPLISDTVLLSELLGNLLDNAVKYSGAGGQVVLCAERDGHLALVTIEDSGPG
IPEAEREQVFRRFYRAPDRPDVPGSGLGLSIVKVIADLLHISIVLDRSPDLGGLRVTLRMTLSPLLYHEAAGAAARG

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=307, Percent_Identity=31.9218241042345, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1790346, Length=262, Percent_Identity=30.5343511450382, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789403, Length=240, Percent_Identity=32.0833333333333, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788279, Length=323, Percent_Identity=27.2445820433437, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786783, Length=283, Percent_Identity=27.208480565371, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=30.7017543859649, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790861, Length=290, Percent_Identity=26.2068965517241, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=194, Percent_Identity=28.3505154639175, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787894, Length=240, Percent_Identity=32.0833333333333, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=275, Percent_Identity=26.1818181818182, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=25.2136752136752, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=212, Percent_Identity=28.3018867924528, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=27.8969957081545, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51387; Mature: 51387

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDARRSLKRAVLLNLLAPVLLLAVAIGAGGYLTITSVVESSHDRLLDGSLMAIAERLAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHH
ESGEVVVDMPQVALGMLETKTQDNVYYLVASDSGPVTGYPDLPLGKMAAAEPGQPTHWDG
CCCCEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TYRGNAVRLAAVARRVYGVERPVIVAVAETRLARNQLRNEMLRNLGVAEAALILAIAVLA
CCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
WVSVERGLMPLADLSRQIDTRAVSDWRDLRPLDLSGVPQEAMAPATAINAMFERLRSATA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLRRFTADASHQMRTPLAIVRMHVDLLRRESSDPELRSSVLAELDQGAERLERLITQLLT
HHHHHHCCCHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARADESAVAAAGGTPCDLGEVIEYVIAERIAGIPPDTQISCLIRHRPLPLISDTVLLSE
HHCCCCCHHEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHH
LLGNLLDNAVKYSGAGGQVVLCAERDGHLALVTIEDSGPGIPEAEREQVFRRFYRAPDRP
HHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCC
DVPGSGLGLSIVKVIADLLHISIVLDRSPDLGGLRVTLRMTLSPLLYHEAAGAAARG
CCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRDARRSLKRAVLLNLLAPVLLLAVAIGAGGYLTITSVVESSHDRLLDGSLMAIAERLAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHH
ESGEVVVDMPQVALGMLETKTQDNVYYLVASDSGPVTGYPDLPLGKMAAAEPGQPTHWDG
CCCCEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TYRGNAVRLAAVARRVYGVERPVIVAVAETRLARNQLRNEMLRNLGVAEAALILAIAVLA
CCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
WVSVERGLMPLADLSRQIDTRAVSDWRDLRPLDLSGVPQEAMAPATAINAMFERLRSATA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLRRFTADASHQMRTPLAIVRMHVDLLRRESSDPELRSSVLAELDQGAERLERLITQLLT
HHHHHHCCCHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARADESAVAAAGGTPCDLGEVIEYVIAERIAGIPPDTQISCLIRHRPLPLISDTVLLSE
HHCCCCCHHEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHH
LLGNLLDNAVKYSGAGGQVVLCAERDGHLALVTIEDSGPGIPEAEREQVFRRFYRAPDRP
HHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCC
DVPGSGLGLSIVKVIADLLHISIVLDRSPDLGGLRVTLRMTLSPLLYHEAAGAAARG
CCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]