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The map label for this gene is yfgC [C]

Identifier: 154246174

GI number: 154246174

Start: 2491830

End: 2493392

Strand: Reverse

Name: yfgC [C]

Synonym: Xaut_2231

Alternate gene names: 154246174

Gene position: 2493392-2491830 (Counterclockwise)

Preceding gene: 154246175

Following gene: 154246173

Centisome position: 46.97

GC content: 68.97

Gene sequence:

>1563_bases
GTGCGGGACGTGAGGCAACAACGGCCAGGCGACAGGACGGAGCGGGCGACGCAGCCGGCGGCCGGGCGCGCCACATGCCG
CTGGGGCATGCGCCATTGGAGCGCCTTCGCCCGCGCGCTGCCGCTGCTGTTCCCGCTGTTGCTGTCGGCCTGCGCCGGCC
TCGACCTCGAGCAGGCGAGCGTGCCTTTGACCTCGCCCGCCTCGGCGTCCGAATACGCCGACATGTCGCCCAACCAGCGC
CGTGAGCATGAGCGCCTGGTGGCGAGCTATGGCGGCGCCTACAACGATCCCGAGCTGAAAGCCCTGATCCAGCAGGTGGT
GGAGCGCCTTGTGGCCGCTTCCGAGCGGCCGGACCTGAAATATCGCGTCACCGTGCTCAACTCGCCGGCCATCAACGCCT
TTGCCCTGCCGGACGGCTCGCTCTACGTCACCCGCGGCCTGCTCTCGCTCGCCAACGACACGTCCGAGCTGTCGTCGGTG
CTGGCCCATGAGATGGCCCATGTCATCGCCCGCCACGCCACCATCCGCGAGGACCAGGTGAAGCAGGCGGTGCTGGTCAG
CCGCGTCATCTCCGACGTGGTCAACGATCCCGACCTGGGGGCGCTGGCCATGCAGAAGAGCCGGAGGACGCTCGCCTCGT
TCTCCCGCGGGCAGGAGCTGGAGGCCGACGCCATCGGGGTGGGCATCGCCGCGCGCGCGGGCTTTGATCCCTACGGCGCA
TCGCGCTTCCTCACCGACATGGGCCGCTTCGGCGACCTGAAGAGCGCGGCCTTCTCCGGCTCGTCCTCCACCACGCCGGA
CATGGACTTCCTGTCCTCCCATCCGGCGACGCCCGAGCGCATCTCCATCGCCATCGCCAATGCCCGGCAATATGCCGAAA
ACGCCAAGCCCGGCGACGGCGAACGCGATCGCAACGCCTATTTCTCCGCCATCGACGGCATGGTCTATGGCGACGACCCC
AAGGAAGGCTTCGTGCGCGGGCGCAAGTTCTTCCATCCCAAGCTGGGCTTCACCTTCACCGCGCCCGAGGGCTTCTCGCT
GGAGAACACCTCCCAGGCGGTGCTGGGCGCCACCCAGACCGGGCGGGAGGCGCTGCGCCTCGACGCAGTGCGGGTCGCCC
CGGACCAGTCGCTGGCGCAGTATCTGTCCTCCGGCTGGGTCGAGGGGGTGGAGATCAACACGGTGGAAAGCCTCACCGTG
AACGGCTTCACCGCCGCCACCGCCATCGCCCGCGGCGACCAGTGGTCGTTCCGCATGTTCGCCATCCGCTTCGGATCGGA
CGTGTACCGCCTCATCTTCGCGGCGCGGGAGCTGACCCCGGAGCTGGACAAGCAGTTCCGCGCCGCCGCCGACACCTTCC
GCCGCGTCTCCTCCGGCGAGGCGGAGACGGTGAAGCCGCTGCGGGTGCGCATCGTCACCGCCGGGCTGGGCGACAATCTG
GAGAAGGTGGCCGCCCGCATGCAGGTGCCGGACCGGCCCATGGAACGCTTCCTGATCCTCAACGGGCTCGATGCGACGGC
CAAGCTCAAGTACGGCGAGAAGGTGAAGATCATCTCCGAGTGA

Upstream 100 bases:

>100_bases
TGCTGCGGCGGCCGGGCGAGATCGCCCTTCTGGCCGGCGCGCAGGCGCCGGTAACGCGCGCAAGGCGCGGTGGCGAGTGA
CACAAGTGCATGAGGTTTCG

Downstream 100 bases:

>100_bases
GGCGGGGCGGCGCGTCAAAGCCCCCGCTCCCGCCGAGTTGATCAGCCTCAAGCCGCGGCCCATCCTAGGTTTGCTATCAT
CGCTTCTCCCGAAAGGGGGA

Product: peptidase M48 Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MRDVRQQRPGDRTERATQPAAGRATCRWGMRHWSAFARALPLLFPLLLSACAGLDLEQASVPLTSPASASEYADMSPNQR
REHERLVASYGGAYNDPELKALIQQVVERLVAASERPDLKYRVTVLNSPAINAFALPDGSLYVTRGLLSLANDTSELSSV
LAHEMAHVIARHATIREDQVKQAVLVSRVISDVVNDPDLGALAMQKSRRTLASFSRGQELEADAIGVGIAARAGFDPYGA
SRFLTDMGRFGDLKSAAFSGSSSTTPDMDFLSSHPATPERISIAIANARQYAENAKPGDGERDRNAYFSAIDGMVYGDDP
KEGFVRGRKFFHPKLGFTFTAPEGFSLENTSQAVLGATQTGREALRLDAVRVAPDQSLAQYLSSGWVEGVEINTVESLTV
NGFTAATAIARGDQWSFRMFAIRFGSDVYRLIFAARELTPELDKQFRAAADTFRRVSSGEAETVKPLRVRIVTAGLGDNL
EKVAARMQVPDRPMERFLILNGLDATAKLKYGEKVKIISE

Sequences:

>Translated_520_residues
MRDVRQQRPGDRTERATQPAAGRATCRWGMRHWSAFARALPLLFPLLLSACAGLDLEQASVPLTSPASASEYADMSPNQR
REHERLVASYGGAYNDPELKALIQQVVERLVAASERPDLKYRVTVLNSPAINAFALPDGSLYVTRGLLSLANDTSELSSV
LAHEMAHVIARHATIREDQVKQAVLVSRVISDVVNDPDLGALAMQKSRRTLASFSRGQELEADAIGVGIAARAGFDPYGA
SRFLTDMGRFGDLKSAAFSGSSSTTPDMDFLSSHPATPERISIAIANARQYAENAKPGDGERDRNAYFSAIDGMVYGDDP
KEGFVRGRKFFHPKLGFTFTAPEGFSLENTSQAVLGATQTGREALRLDAVRVAPDQSLAQYLSSGWVEGVEINTVESLTV
NGFTAATAIARGDQWSFRMFAIRFGSDVYRLIFAARELTPELDKQFRAAADTFRRVSSGEAETVKPLRVRIVTAGLGDNL
EKVAARMQVPDRPMERFLILNGLDATAKLKYGEKVKIISE
>Mature_520_residues
MRDVRQQRPGDRTERATQPAAGRATCRWGMRHWSAFARALPLLFPLLLSACAGLDLEQASVPLTSPASASEYADMSPNQR
REHERLVASYGGAYNDPELKALIQQVVERLVAASERPDLKYRVTVLNSPAINAFALPDGSLYVTRGLLSLANDTSELSSV
LAHEMAHVIARHATIREDQVKQAVLVSRVISDVVNDPDLGALAMQKSRRTLASFSRGQELEADAIGVGIAARAGFDPYGA
SRFLTDMGRFGDLKSAAFSGSSSTTPDMDFLSSHPATPERISIAIANARQYAENAKPGDGERDRNAYFSAIDGMVYGDDP
KEGFVRGRKFFHPKLGFTFTAPEGFSLENTSQAVLGATQTGREALRLDAVRVAPDQSLAQYLSSGWVEGVEINTVESLTV
NGFTAATAIARGDQWSFRMFAIRFGSDVYRLIFAARELTPELDKQFRAAADTFRRVSSGEAETVKPLRVRIVTAGLGDNL
EKVAARMQVPDRPMERFLILNGLDATAKLKYGEKVKIISE

Specific function: Unknown

COG id: COG4784

COG function: function code R; Putative Zn-dependent protease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TPR repeat [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=174, Percent_Identity=30.4597701149425, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788840, Length=212, Percent_Identity=31.1320754716981, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322940, Length=165, Percent_Identity=30.3030303030303, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915
- InterPro:   IPR011716
- InterPro:   IPR011990 [H]

Pfam domain/function: PF01435 Peptidase_M48; PF07720 TPR_3 [H]

EC number: NA

Molecular weight: Translated: 56767; Mature: 56767

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDVRQQRPGDRTERATQPAAGRATCRWGMRHWSAFARALPLLFPLLLSACAGLDLEQAS
CCCHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCC
VPLTSPASASEYADMSPNQRREHERLVASYGGAYNDPELKALIQQVVERLVAASERPDLK
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCE
YRVTVLNSPAINAFALPDGSLYVTRGLLSLANDTSELSSVLAHEMAHVIARHATIREDQV
EEEEEECCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
KQAVLVSRVISDVVNDPDLGALAMQKSRRTLASFSRGQELEADAIGVGIAARAGFDPYGA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHCCCCCCCCH
SRFLTDMGRFGDLKSAAFSGSSSTTPDMDFLSSHPATPERISIAIANARQYAENAKPGDG
HHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCHHEEEEEHHHHHHHHCCCCCCC
ERDRNAYFSAIDGMVYGDDPKEGFVRGRKFFHPKLGFTFTAPEGFSLENTSQAVLGATQT
CCHHHHHHHHHCCCEECCCCHHHHHHCHHHCCCCCCEEEECCCCCCCCCCCHHHHCCCCC
GREALRLDAVRVAPDQSLAQYLSSGWVEGVEINTVESLTVNGFTAATAIARGDQWSFRMF
CHHHHHHHHEEECCCHHHHHHHHCCCCCCEEECCCCEEEECCHHHHHHHHCCCCCEEEEE
AIRFGSDVYRLIFAARELTPELDKQFRAAADTFRRVSSGEAETVKPLRVRIVTAGLGDNL
EEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCH
EKVAARMQVPDRPMERFLILNGLDATAKLKYGEKVKIISE
HHHHHHHCCCCCHHHHEEEEECCCCCEEECCCCEEEEECC
>Mature Secondary Structure
MRDVRQQRPGDRTERATQPAAGRATCRWGMRHWSAFARALPLLFPLLLSACAGLDLEQAS
CCCHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCC
VPLTSPASASEYADMSPNQRREHERLVASYGGAYNDPELKALIQQVVERLVAASERPDLK
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCE
YRVTVLNSPAINAFALPDGSLYVTRGLLSLANDTSELSSVLAHEMAHVIARHATIREDQV
EEEEEECCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
KQAVLVSRVISDVVNDPDLGALAMQKSRRTLASFSRGQELEADAIGVGIAARAGFDPYGA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHCCCCCCCCH
SRFLTDMGRFGDLKSAAFSGSSSTTPDMDFLSSHPATPERISIAIANARQYAENAKPGDG
HHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCHHEEEEEHHHHHHHHCCCCCCC
ERDRNAYFSAIDGMVYGDDPKEGFVRGRKFFHPKLGFTFTAPEGFSLENTSQAVLGATQT
CCHHHHHHHHHCCCEECCCCHHHHHHCHHHCCCCCCEEEECCCCCCCCCCCHHHHCCCCC
GREALRLDAVRVAPDQSLAQYLSSGWVEGVEINTVESLTVNGFTAATAIARGDQWSFRMF
CHHHHHHHHEEECCCHHHHHHHHCCCCCCEEECCCCEEEECCHHHHHHHHCCCCCEEEEE
AIRFGSDVYRLIFAARELTPELDKQFRAAADTFRRVSSGEAETVKPLRVRIVTAGLGDNL
EEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCH
EKVAARMQVPDRPMERFLILNGLDATAKLKYGEKVKIISE
HHHHHHHCCCCCHHHHEEEEECCCCCEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]