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The map label for this gene is hypD [H]

Identifier: 154246129

GI number: 154246129

Start: 2445218

End: 2446342

Strand: Direct

Name: hypD [H]

Synonym: Xaut_2186

Alternate gene names: 154246129

Gene position: 2445218-2446342 (Clockwise)

Preceding gene: 154246128

Following gene: 154246130

Centisome position: 46.06

GC content: 68.36

Gene sequence:

>1125_bases
ATGCGCTACGTCGACGAATTCCGCGACCCCGCCCTCGCCTCGGCGCTGGTGAAGGAGATCGGCGCCATCTCGGTCCGGCT
GGAACGCGGCCGCGACCGGCCGTTCGCCATCATGGAGGTGTGCGGCGGGCATACCCACGCCATCTTCCGCTATGGGCTGG
AATGCCTGCTGCCGGACCTCGTGGAATTCGTCCATGGTCCGGGCTGCCCGGTGTGCGTGCTGCCCATGGGCCGGGTGGAC
GATTGCGTCGCCATCGCCGAGCGGGAAGAGGTGATCTTCGCCACCTTCGGCGACGCCATGCGCGTGCCGGGTTCGAAGAA
GAGCCTGCTCCAGGCCAAGGCGGACGGGGCGGACGTGCGCATGGTCTATTCGCCCCTTGATGCGCTCACCTTGGCGAAGC
GCAATCCCGAGCGGCAGGTGGTGTTCTTCGGCCTCGGCTTCGAGACCACCATGCCCTCCACCGCGCTCACCGTGTTGCGG
GCGGCGCGGGAGCGGGTTCGGAACTTCTCCCTGTTCTGCAACCACATCACCATCATCCCCACGCTCCGGGCGCTGCTGGA
GCAGCCGGACCTCGGCATCGACGGCTTCATCGGGCCGGGGCATGTCTCCATGGTCATCGGAACGTCGCCTTACCGCTTCA
TCGCCGAGGAGTTCCACAAGCCCCTCGTGGTGGCGGGCTTCGAGCCCATCGACCTGTTGCAATCCCTGCTGATGGTGCTG
CGCCAGATCGAGGCCGGGACGGCGCGGATCGAGAACCAGTATGCCCGCGTGGTGCCGGAGCATGGCAATCCGCAGGCGCT
GAAGGCGGTGGAAGAGGTCTACGAGCCGCGCGAGACCTTCGAGTGGCGCGGGCTCGGCTCCATCGCCGGCTCCGGGGTGC
GGCTCCGGGCGCCCTATGCTGCGTTCGATGCGGAGAAGCGCTTCGCCGTGCCGGACGTGAAGGTGGCGGACCCCTCCTCC
TGCCGCTGCGGCGAGGTGCTCACCGGCGCGGTGAAGCCGTGGGCCTGCCCGGAGTTCGGCACCGGCTGCACCCCCGAGAC
GCCGCTGGGCGCGCTCATGGTGTCGTCCGAAGGCTCTTGCGCCGCCTATTACCAATATGGTGGCGTGCGGGGAGAAGCCG
CATGA

Upstream 100 bases:

>100_bases
CTCAAGGTGCTCACCGAGATCGGCGAGGCGGCGGCGGAAATGGAAGCGCTGACAAAAGGCAGCGTCGATCTTCACCCCAC
CACTGCCTGAGGAGACGGCC

Downstream 100 bases:

>100_bases
ACATCCCCGTCCTCCCCCCCACCCGGCGCCGGCCGCTGAGCCACAAGACCGTGACGCTCGCCCATGGCGGCGGCGGCAGC
GCCATGCGCGACCTCATCGA

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRYVDEFRDPALASALVKEIGAISVRLERGRDRPFAIMEVCGGHTHAIFRYGLECLLPDLVEFVHGPGCPVCVLPMGRVD
DCVAIAEREEVIFATFGDAMRVPGSKKSLLQAKADGADVRMVYSPLDALTLAKRNPERQVVFFGLGFETTMPSTALTVLR
AARERVRNFSLFCNHITIIPTLRALLEQPDLGIDGFIGPGHVSMVIGTSPYRFIAEEFHKPLVVAGFEPIDLLQSLLMVL
RQIEAGTARIENQYARVVPEHGNPQALKAVEEVYEPRETFEWRGLGSIAGSGVRLRAPYAAFDAEKRFAVPDVKVADPSS
CRCGEVLTGAVKPWACPEFGTGCTPETPLGALMVSSEGSCAAYYQYGGVRGEAA

Sequences:

>Translated_374_residues
MRYVDEFRDPALASALVKEIGAISVRLERGRDRPFAIMEVCGGHTHAIFRYGLECLLPDLVEFVHGPGCPVCVLPMGRVD
DCVAIAEREEVIFATFGDAMRVPGSKKSLLQAKADGADVRMVYSPLDALTLAKRNPERQVVFFGLGFETTMPSTALTVLR
AARERVRNFSLFCNHITIIPTLRALLEQPDLGIDGFIGPGHVSMVIGTSPYRFIAEEFHKPLVVAGFEPIDLLQSLLMVL
RQIEAGTARIENQYARVVPEHGNPQALKAVEEVYEPRETFEWRGLGSIAGSGVRLRAPYAAFDAEKRFAVPDVKVADPSS
CRCGEVLTGAVKPWACPEFGTGCTPETPLGALMVSSEGSCAAYYQYGGVRGEAA
>Mature_374_residues
MRYVDEFRDPALASALVKEIGAISVRLERGRDRPFAIMEVCGGHTHAIFRYGLECLLPDLVEFVHGPGCPVCVLPMGRVD
DCVAIAEREEVIFATFGDAMRVPGSKKSLLQAKADGADVRMVYSPLDALTLAKRNPERQVVFFGLGFETTMPSTALTVLR
AARERVRNFSLFCNHITIIPTLRALLEQPDLGIDGFIGPGHVSMVIGTSPYRFIAEEFHKPLVVAGFEPIDLLQSLLMVL
RQIEAGTARIENQYARVVPEHGNPQALKAVEEVYEPRETFEWRGLGSIAGSGVRLRAPYAAFDAEKRFAVPDVKVADPSS
CRCGEVLTGAVKPWACPEFGTGCTPETPLGALMVSSEGSCAAYYQYGGVRGEAA

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=373, Percent_Identity=60.857908847185, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40749; Mature: 40749

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVDEFRDPALASALVKEIGAISVRLERGRDRPFAIMEVCGGHTHAIFRYGLECLLPDL
CCCHHHHCCHHHHHHHHHHHHHEEEEEECCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHH
VEFVHGPGCPVCVLPMGRVDDCVAIAEREEVIFATFGDAMRVPGSKKSLLQAKADGADVR
HHHHCCCCCCEEEEECCCCCHHHHHHCCCCEEEEECCCHHCCCCCHHHHHHHCCCCCCEE
MVYSPLDALTLAKRNPERQVVFFGLGFETTMPSTALTVLRAARERVRNFSLFCNHITIIP
EEECCHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRALLEQPDLGIDGFIGPGHVSMVIGTSPYRFIAEEFHKPLVVAGFEPIDLLQSLLMVL
HHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
RQIEAGTARIENQYARVVPEHGNPQALKAVEEVYEPRETFEWRGLGSIAGSGVRLRAPYA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHCCCCCCHHCCCCEEEECCHH
AFDAEKRFAVPDVKVADPSSCRCGEVLTGAVKPWACPEFGTGCTPETPLGALMVSSEGSC
HHCCCCCCCCCCCEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCE
AAYYQYGGVRGEAA
EEEEECCCCCCCCC
>Mature Secondary Structure
MRYVDEFRDPALASALVKEIGAISVRLERGRDRPFAIMEVCGGHTHAIFRYGLECLLPDL
CCCHHHHCCHHHHHHHHHHHHHEEEEEECCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHH
VEFVHGPGCPVCVLPMGRVDDCVAIAEREEVIFATFGDAMRVPGSKKSLLQAKADGADVR
HHHHCCCCCCEEEEECCCCCHHHHHHCCCCEEEEECCCHHCCCCCHHHHHHHCCCCCCEE
MVYSPLDALTLAKRNPERQVVFFGLGFETTMPSTALTVLRAARERVRNFSLFCNHITIIP
EEECCHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRALLEQPDLGIDGFIGPGHVSMVIGTSPYRFIAEEFHKPLVVAGFEPIDLLQSLLMVL
HHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
RQIEAGTARIENQYARVVPEHGNPQALKAVEEVYEPRETFEWRGLGSIAGSGVRLRAPYA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHCCCCCCHHCCCCEEEECCHH
AFDAEKRFAVPDVKVADPSSCRCGEVLTGAVKPWACPEFGTGCTPETPLGALMVSSEGSC
HHCCCCCCCCCCCEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCE
AAYYQYGGVRGEAA
EEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]