Click here to switch to the map view.

The map label for this gene is hofF [H]

Identifier: 154246051

GI number: 154246051

Start: 2368957

End: 2370168

Strand: Direct

Name: hofF [H]

Synonym: Xaut_2108

Alternate gene names: 154246051

Gene position: 2368957-2370168 (Clockwise)

Preceding gene: 154246050

Following gene: 154246052

Centisome position: 44.62

GC content: 71.29

Gene sequence:

>1212_bases
ATGGCGACCTTCACCTACAGGGCCCTCACCCAGGCCGGACAGATCGTGAGCGGCGAGATCACCGCGCCCACCGAGGCGGA
GGTGCGCCGGCGCATCGAGTTCCTCGGCCTCATGCCGGTGGAGACGATCCCGGCGCGGCCGAAGGGCGAGGGCGGGCGGT
TCGGCCTGTCGCTGGGCGGGCCGAAGGCGGAGGACGTGACCCTCTTCACCCGCGACCTCGCGCTGCTGTTGAAGGCCGGC
GCGCGGCTCGACGAGGCGCTGGAGCTGTTGTCCGGCGATGCGGACCTCGGCCGCATGCGGGCGGTGGTGCGCAAGCTGCG
CGCCGACGTGCTCGCCGGCCAGAGCTTCGCCGAGGCGGCGGCGGGGGAGCCCAAGCTGTTCCCGCCGGTCTATGTGGCGC
TGGTGCGGGTGGGCGAGGCCTCCGGCACCATGGACCGCATCCTCGACCTGCTCGCCCAGGAGCGCGCGCGGGCCGAGCAG
CTGCGCCGCAAGCTGATGGAAGCGCTGCAATATCCCGCCTTCGTGCTGGCGGCGGCGGGCGGGGTGCTGGTGTTCTTCCT
GTTGTTCGTGCTGCCGCAATTCTCCACCGTGCTGCGCGACATGGGCGCCAAGCTCGATCCGGCGGTGGAAATGCTGCTGA
ACCTGTCGGATCTTGCCCAGGCCCATGGCGCCGCGCTGGGGGCGGGGGCCTGCGGTCTGGTGGCCATCGCCTGGCTGGTG
CTGCGCCGGCCGGCTACGCGAACGGCCGTGATGGGCGCGCTGGCGCGGCTGCCGCTGGTGCGCACCATTCTCACCTTCCG
CCGCTCGGCCGTGTTCTGCCGCAACCTCTCCATCCTGCTGGGCAACGGCGTGACGCTGACCAGCGCCCTGCGCATCATCG
TGGAGGTGATGGCGGCAGGCGACGACGCTTCCGTCTGGGCCGCCACCTCGGACAAGGTGCGCCAGGGCGCGCGGCTGTCG
GATGCGGTGGCGGCCGGCGCGGCGCTGCCGCCCATGGCGGTGCGCATGCTGCGCCTCGGCGAGGAGACCGGCCAGCTTGC
CATGCTGTCGGGCCGCATCGCCGATTTCTACGAGGAAAAGCTCCAGCGGTCCCTCGCGAAGGTGGTCGCCATCATCGGAC
CCGCCGCCATTGTCACCATCAGCGTCGTCGTCGGCGGCCTGATCGTTTCCGTCATGACCGCGCTTCTGTCGGTCAGCCAA
AGCATCGGATGA

Upstream 100 bases:

>100_bases
TCGCCGGCGGCATGACCACCATGCTGGACGACGGCATCCTGAAATGCCGGGCCGGCATCACCTCGCCGGCCGAGGTGCTG
CGCGTGACCACCGTGCGCTG

Downstream 100 bases:

>100_bases
ACCGCGTGAACACCAGTCTTCCGGCGGGCCGCGCCCGCATCGCCCAATTCCGCCGCCGGCGCAGGAGCGAGGGCGGCTAC
ACCCTCGTCGAACTGCTGGT

Product: type II secretion system protein

Products: NA

Alternate protein names: Protein transport protein hofF [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MATFTYRALTQAGQIVSGEITAPTEAEVRRRIEFLGLMPVETIPARPKGEGGRFGLSLGGPKAEDVTLFTRDLALLLKAG
ARLDEALELLSGDADLGRMRAVVRKLRADVLAGQSFAEAAAGEPKLFPPVYVALVRVGEASGTMDRILDLLAQERARAEQ
LRRKLMEALQYPAFVLAAAGGVLVFFLLFVLPQFSTVLRDMGAKLDPAVEMLLNLSDLAQAHGAALGAGACGLVAIAWLV
LRRPATRTAVMGALARLPLVRTILTFRRSAVFCRNLSILLGNGVTLTSALRIIVEVMAAGDDASVWAATSDKVRQGARLS
DAVAAGAALPPMAVRMLRLGEETGQLAMLSGRIADFYEEKLQRSLAKVVAIIGPAAIVTISVVVGGLIVSVMTALLSVSQ
SIG

Sequences:

>Translated_403_residues
MATFTYRALTQAGQIVSGEITAPTEAEVRRRIEFLGLMPVETIPARPKGEGGRFGLSLGGPKAEDVTLFTRDLALLLKAG
ARLDEALELLSGDADLGRMRAVVRKLRADVLAGQSFAEAAAGEPKLFPPVYVALVRVGEASGTMDRILDLLAQERARAEQ
LRRKLMEALQYPAFVLAAAGGVLVFFLLFVLPQFSTVLRDMGAKLDPAVEMLLNLSDLAQAHGAALGAGACGLVAIAWLV
LRRPATRTAVMGALARLPLVRTILTFRRSAVFCRNLSILLGNGVTLTSALRIIVEVMAAGDDASVWAATSDKVRQGARLS
DAVAAGAALPPMAVRMLRLGEETGQLAMLSGRIADFYEEKLQRSLAKVVAIIGPAAIVTISVVVGGLIVSVMTALLSVSQ
SIG
>Mature_402_residues
ATFTYRALTQAGQIVSGEITAPTEAEVRRRIEFLGLMPVETIPARPKGEGGRFGLSLGGPKAEDVTLFTRDLALLLKAGA
RLDEALELLSGDADLGRMRAVVRKLRADVLAGQSFAEAAAGEPKLFPPVYVALVRVGEASGTMDRILDLLAQERARAEQL
RRKLMEALQYPAFVLAAAGGVLVFFLLFVLPQFSTVLRDMGAKLDPAVEMLLNLSDLAQAHGAALGAGACGLVAIAWLVL
RRPATRTAVMGALARLPLVRTILTFRRSAVFCRNLSILLGNGVTLTSALRIIVEVMAAGDDASVWAATSDKVRQGARLSD
AVAAGAALPPMAVRMLRLGEETGQLAMLSGRIADFYEEKLQRSLAKVVAIIGPAAIVTISVVVGGLIVSVMTALLSVSQS
IG

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=403, Percent_Identity=31.2655086848635, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI1786295, Length=332, Percent_Identity=25.3012048192771, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR011850
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 42579; Mature: 42448

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFTYRALTQAGQIVSGEITAPTEAEVRRRIEFLGLMPVETIPARPKGEGGRFGLSLGG
CCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCC
PKAEDVTLFTRDLALLLKAGARLDEALELLSGDADLGRMRAVVRKLRADVLAGQSFAEAA
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
AGEPKLFPPVYVALVRVGEASGTMDRILDLLAQERARAEQLRRKLMEALQYPAFVLAAAG
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GVLVFFLLFVLPQFSTVLRDMGAKLDPAVEMLLNLSDLAQAHGAALGAGACGLVAIAWLV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHH
LRRPATRTAVMGALARLPLVRTILTFRRSAVFCRNLSILLGNGVTLTSALRIIVEVMAAG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCC
DDASVWAATSDKVRQGARLSDAVAAGAALPPMAVRMLRLGEETGQLAMLSGRIADFYEEK
CCCCEEECCHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHH
LQRSLAKVVAIIGPAAIVTISVVVGGLIVSVMTALLSVSQSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATFTYRALTQAGQIVSGEITAPTEAEVRRRIEFLGLMPVETIPARPKGEGGRFGLSLGG
CCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCC
PKAEDVTLFTRDLALLLKAGARLDEALELLSGDADLGRMRAVVRKLRADVLAGQSFAEAA
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
AGEPKLFPPVYVALVRVGEASGTMDRILDLLAQERARAEQLRRKLMEALQYPAFVLAAAG
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GVLVFFLLFVLPQFSTVLRDMGAKLDPAVEMLLNLSDLAQAHGAALGAGACGLVAIAWLV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHH
LRRPATRTAVMGALARLPLVRTILTFRRSAVFCRNLSILLGNGVTLTSALRIIVEVMAAG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCC
DDASVWAATSDKVRQGARLSDAVAAGAALPPMAVRMLRLGEETGQLAMLSGRIADFYEEK
CCCCEEECCHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHH
LQRSLAKVVAIIGPAAIVTISVVVGGLIVSVMTALLSVSQSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7896718 [H]