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The map label for this gene is dacC [H]

Identifier: 154245869

GI number: 154245869

Start: 2177565

End: 2179091

Strand: Direct

Name: dacC [H]

Synonym: Xaut_1925

Alternate gene names: 154245869

Gene position: 2177565-2179091 (Clockwise)

Preceding gene: 154245868

Following gene: 154245870

Centisome position: 41.02

GC content: 69.55

Gene sequence:

>1527_bases
TTGGCGCGCACGAAATCCAGTCCCGGCGCCCGGGCGACTTCCATGGGCGATGCCCGCCGTGGACTTTGTCTCGGTCTTGC
CGCTGCGGTGCTCGGCGTCGGGCTCGCCGGCTCGTTCCTCGTCCATCCCGCGCAGGCCAATCCGGTGCTTCTGGTGGAGG
CCGACACCGGCCGGGTGATCGAGCAGAAGGAAGCCGGCCGGCCCTGGCATCCCGCCTCCGTCACCAAGCTGATGACCGTC
TATGTGGCGCTCAACGCGGTGAAGAACGGGCGCCTCACCCTGGACACGCCCCTTACCGTCTCGGCCGCCGCCGCCTCCCA
GCAGCCCTCCAAGATGGGCTTCAAGCCGGGCACCGTGGTCACCCTCGACAACGCCATGAAGATGGTGCTGGTGAAGTCCG
CCAACGACATGGCCTGGGTGGTGGGCGAAGGCGTCGCCGGCTCCATGCCCGCCTTTGTGGCGGAGATGAACGCCACCGCC
GCCCATCTCGGCATGAGCGGCACCCATTTCGAGAATCCCAACGGCCTGCCGGACCCGGACCAGATCACCACCGCCCGTGA
CCTCGCCATCCTGGCGCGGGCCATCATCTACCATTTCCCCGAGCACGAGGCCCTGTTCCGCATCCCCGCCATCAAGATCG
GCAAGGCGGTGCTGCGCAACTACAACCGCCTGATCGACCGCTATCCCGGCGCCGACGGCATGAAGACCGGCTTCGTCTGC
GGCTCCGGCTATAATCTGGTGGCCACCGCCACCCGCGGCAACAAGCGCCTCATCGCCGTGATCCTCGGCGCCCGCTCCGG
CACCGCCCGCACCGAGCAGGCGGCGCTGATGTTCGAGAAGGGCTTCCAGTCGTCCTGGGGTGTGTTCGGCGCTGCGCAGC
CGCTTTTGTCCAACATTTCCAACAGCGGCGGCCCGGCCTACGACATGAAGGCCGAGGTCTGTGGCGGCAAGCGCGCCGTC
ACCGCCTCCGAGGCCGATGACGAGTCCGAAGGCAGCAGCGGCGGCTTCGCCTTTGCCGCGCCGGTGCTGCCCAAGTCCGG
TGCCGAGCTGCTGCAGACCCTGCCGCCCTCCATGCCGCCGGTGGTGGTCTATGTGGGCACCCGCAACGCGCCGCAGGATC
TGGCATCGGCCTATCCCGAGGAAGAGAAGCCGAAGAAGAAGCCGGGCGCCAAGGACACCAAGCAGGCCAAGGCGTCCGCC
GGCTCCGAGAGCGCGTCGGCCGAAAGCGGCGACGGCGCCAAGCCCACCGCCAAGCCGAAGCCCAGGACCGCTGATGGCAA
GACCGCCGGCAGCAAGCCCTCGACCGCGACGGCCAGCACCGGCGACGAGCCCAAGGCTGCGGCCAAGCCCAAGAGTGCCA
GCACCTCCGGCGACAAGCCGGCGAGCGGTACCGCCCAGAAGAAGCAGGTACAGCCCCAGGCGCCGGTCACCGCCGGCTCG
GTGCCCGCGTCGAAGCCCAAGCCCAAGCCGAAGCCCGCCGAAACCCCGGCCGAAAGCGCCGCCCCGGCCCCCAAGCCCGC
CACCTGA

Upstream 100 bases:

>100_bases
CCTTTCGCCGCCCTATTGCGACTTTCCCGGCGGGGCGAAAGCGGGTAATGAAGGACCAATAGGGTGATGAGCTATTCTGG
CTGACACGGGAGCTGAGCGG

Downstream 100 bases:

>100_bases
GGCGCGCGCCGAAACGGGCGCCGTTCCAGCAGTCTTCATGCGGCCCGCAAGTGCCGCTCCGCAGGCGCTGTAGGGCGGGT
GGGCATGCGCGCCCCTCCGG

Product: Serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MARTKSSPGARATSMGDARRGLCLGLAAAVLGVGLAGSFLVHPAQANPVLLVEADTGRVIEQKEAGRPWHPASVTKLMTV
YVALNAVKNGRLTLDTPLTVSAAAASQQPSKMGFKPGTVVTLDNAMKMVLVKSANDMAWVVGEGVAGSMPAFVAEMNATA
AHLGMSGTHFENPNGLPDPDQITTARDLAILARAIIYHFPEHEALFRIPAIKIGKAVLRNYNRLIDRYPGADGMKTGFVC
GSGYNLVATATRGNKRLIAVILGARSGTARTEQAALMFEKGFQSSWGVFGAAQPLLSNISNSGGPAYDMKAEVCGGKRAV
TASEADDESEGSSGGFAFAAPVLPKSGAELLQTLPPSMPPVVVYVGTRNAPQDLASAYPEEEKPKKKPGAKDTKQAKASA
GSESASAESGDGAKPTAKPKPRTADGKTAGSKPSTATASTGDEPKAAAKPKSASTSGDKPASGTAQKKQVQPQAPVTAGS
VPASKPKPKPKPAETPAESAAPAPKPAT

Sequences:

>Translated_508_residues
MARTKSSPGARATSMGDARRGLCLGLAAAVLGVGLAGSFLVHPAQANPVLLVEADTGRVIEQKEAGRPWHPASVTKLMTV
YVALNAVKNGRLTLDTPLTVSAAAASQQPSKMGFKPGTVVTLDNAMKMVLVKSANDMAWVVGEGVAGSMPAFVAEMNATA
AHLGMSGTHFENPNGLPDPDQITTARDLAILARAIIYHFPEHEALFRIPAIKIGKAVLRNYNRLIDRYPGADGMKTGFVC
GSGYNLVATATRGNKRLIAVILGARSGTARTEQAALMFEKGFQSSWGVFGAAQPLLSNISNSGGPAYDMKAEVCGGKRAV
TASEADDESEGSSGGFAFAAPVLPKSGAELLQTLPPSMPPVVVYVGTRNAPQDLASAYPEEEKPKKKPGAKDTKQAKASA
GSESASAESGDGAKPTAKPKPRTADGKTAGSKPSTATASTGDEPKAAAKPKSASTSGDKPASGTAQKKQVQPQAPVTAGS
VPASKPKPKPKPAETPAESAAPAPKPAT
>Mature_507_residues
ARTKSSPGARATSMGDARRGLCLGLAAAVLGVGLAGSFLVHPAQANPVLLVEADTGRVIEQKEAGRPWHPASVTKLMTVY
VALNAVKNGRLTLDTPLTVSAAAASQQPSKMGFKPGTVVTLDNAMKMVLVKSANDMAWVVGEGVAGSMPAFVAEMNATAA
HLGMSGTHFENPNGLPDPDQITTARDLAILARAIIYHFPEHEALFRIPAIKIGKAVLRNYNRLIDRYPGADGMKTGFVCG
SGYNLVATATRGNKRLIAVILGARSGTARTEQAALMFEKGFQSSWGVFGAAQPLLSNISNSGGPAYDMKAEVCGGKRAVT
ASEADDESEGSSGGFAFAAPVLPKSGAELLQTLPPSMPPVVVYVGTRNAPQDLASAYPEEEKPKKKPGAKDTKQAKASAG
SESASAESGDGAKPTAKPKPRTADGKTAGSKPSTATASTGDEPKAAAKPKSASTSGDKPASGTAQKKQVQPQAPVTAGSV
PASKPKPKPKPAETPAESAAPAPKPAT

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=245, Percent_Identity=36.734693877551, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87082022, Length=247, Percent_Identity=35.6275303643725, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1786851, Length=259, Percent_Identity=32.046332046332, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87082054, Length=231, Percent_Identity=31.1688311688312, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 52050; Mature: 51918

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTKSSPGARATSMGDARRGLCLGLAAAVLGVGLAGSFLVHPAQANPVLLVEADTGRVI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCEE
EQKEAGRPWHPASVTKLMTVYVALNAVKNGRLTLDTPLTVSAAAASQQPSKMGFKPGTVV
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHCCCCCHHCCCCCCEEE
TLDNAMKMVLVKSANDMAWVVGEGVAGSMPAFVAEMNATAAHLGMSGTHFENPNGLPDPD
EECCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCH
QITTARDLAILARAIIYHFPEHEALFRIPAIKIGKAVLRNYNRLIDRYPGADGMKTGFVC
HHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
GSGYNLVATATRGNKRLIAVILGARSGTARTEQAALMFEKGFQSSWGVFGAAQPLLSNIS
CCCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
NSGGPAYDMKAEVCGGKRAVTASEADDESEGSSGGFAFAAPVLPKSGAELLQTLPPSMPP
CCCCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCC
VVVYVGTRNAPQDLASAYPEEEKPKKKPGAKDTKQAKASAGSESASAESGDGAKPTAKPK
EEEEECCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PRTADGKTAGSKPSTATASTGDEPKAAAKPKSASTSGDKPASGTAQKKQVQPQAPVTAGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
VPASKPKPKPKPAETPAESAAPAPKPAT
CCCCCCCCCCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
ARTKSSPGARATSMGDARRGLCLGLAAAVLGVGLAGSFLVHPAQANPVLLVEADTGRVI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCEE
EQKEAGRPWHPASVTKLMTVYVALNAVKNGRLTLDTPLTVSAAAASQQPSKMGFKPGTVV
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHCCCCCHHCCCCCCEEE
TLDNAMKMVLVKSANDMAWVVGEGVAGSMPAFVAEMNATAAHLGMSGTHFENPNGLPDPD
EECCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCH
QITTARDLAILARAIIYHFPEHEALFRIPAIKIGKAVLRNYNRLIDRYPGADGMKTGFVC
HHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
GSGYNLVATATRGNKRLIAVILGARSGTARTEQAALMFEKGFQSSWGVFGAAQPLLSNIS
CCCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
NSGGPAYDMKAEVCGGKRAVTASEADDESEGSSGGFAFAAPVLPKSGAELLQTLPPSMPP
CCCCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCC
VVVYVGTRNAPQDLASAYPEEEKPKKKPGAKDTKQAKASAGSESASAESGDGAKPTAKPK
EEEEECCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PRTADGKTAGSKPSTATASTGDEPKAAAKPKSASTSGDKPASGTAQKKQVQPQAPVTAGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
VPASKPKPKPKPAETPAESAAPAPKPAT
CCCCCCCCCCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]