Click here to switch to the map view.

The map label for this gene is yjiA [H]

Identifier: 154245870

GI number: 154245870

Start: 2179290

End: 2180462

Strand: Direct

Name: yjiA [H]

Synonym: Xaut_1926

Alternate gene names: 154245870

Gene position: 2179290-2180462 (Clockwise)

Preceding gene: 154245869

Following gene: 154245871

Centisome position: 41.05

GC content: 72.8

Gene sequence:

>1173_bases
ATGCCGGGCAACGTGCCCGCCCCAGAGGCGCCCGCCCAAAATGCGCCGGCCGACACGGCGCCCGCCCGCCGTCGCGGACC
GCCGGAGCCCATTCCGGTCACGGTGCTGACCGGCTTCCTCGGCGCCGGCAAGACCACGCTGCTCAATGCCCTGCTGGCCG
ATCCGGGCCTGGCCGACACTGCCGTACTCATCAACGAGTTCGGCGAGGTGGGGCTCGACCATCTGTTCGTGCGGCCGGTG
GAGGAGGGCATCGTCATGCTCGCCTCGGGCTGCCTGTGCTGCACCGTGCGCGGCGACCTGGTGGCGGCGCTGGAGGACCT
TTTGCGCGGCCGCGACAACGACCGCCTGCCGCCGTTTGCCCGCGTCATCATCGAGACCACGGGCCTCGCCGATCCGGCGC
CGGTGATCCACACCCTGATGACCCACCCCTATCTCGGCCTGCGCTACCGGCTCGACGGGCTCGTCTGCGTGGTGGATGCG
GTGAATGCGGACGCCACCCTTGATGCCCATGAGGAGGCGGTGAAGCAGGCGGCCATGGCCGACCGCATCGTCCTCACCAA
GACCGACCTGGTGGCCGACGCGGACCGCCCGCAGCTCGAGGCGCTGCGGGCGCGGCTCAAGAGCCTCGCCCCCGGCGCCC
GGCTGCTGGACGCGGCGGCGGGGGAGGCGCAGGCCGCGTCCATCCTCGGCGCCGGGCTCTATGCGACCGCCGGCAAGGCG
CCGGACGTGGCCCGCTGGCTCGCGGCCGAGGAGGTGGCGGCGGCGGAACCGGACGGCGCGAGCCTCGACCCAAACCGCCA
CGATGCCCGCATCCGGGCCTTCACCTTGGCCACCGACGCCGCCATTCCGGCCGCCACCCTCGACCTGTTCCTGGAGCTGC
TGCGCGCCACCCATGGCGGCAACGTGCTGCGCATGAAGGGCATCGTGAAAGTGGCGGAGGAGCCGGACGCGCCTATCGTG
ATCCACGCCGTGCAGCATGTGATGCACCCGCCCGCGCGCCTGCCCGCCTGGCCGGACGAGGACCATCGCACCCGGCTGGT
GATGATCGTGCGCGACCTCGACCCCAAGGTCATCGCCCGCCTGTTCAACGCCTTCCTCGGCGTGCCGCAGGTGGATACGC
CGGACCGCGCCGCGCTCACCGACAACCCCCTCGCCCCGCCGGGGCTGCGGTGA

Upstream 100 bases:

>100_bases
GGGCGCGATGCGGTGCGGACATCCATCGCCCTTGACCCAGCGCGTCGGCTGATGGAGGCAGAGGGAAGAGACTTCCCTTT
CGTCCTGTGGAGACATCGCG

Downstream 100 bases:

>100_bases
TGCTCAAGGGCATGACGCCTGAGAAAATGACGCCGGCGGATGTGCTCGCCTTCTGGCGGGCGGCGGGCCGGGAGAAATGG
TTCGGCGGCGGCGCGGCGTT

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPGNVPAPEAPAQNAPADTAPARRRGPPEPIPVTVLTGFLGAGKTTLLNALLADPGLADTAVLINEFGEVGLDHLFVRPV
EEGIVMLASGCLCCTVRGDLVAALEDLLRGRDNDRLPPFARVIIETTGLADPAPVIHTLMTHPYLGLRYRLDGLVCVVDA
VNADATLDAHEEAVKQAAMADRIVLTKTDLVADADRPQLEALRARLKSLAPGARLLDAAAGEAQAASILGAGLYATAGKA
PDVARWLAAEEVAAAEPDGASLDPNRHDARIRAFTLATDAAIPAATLDLFLELLRATHGGNVLRMKGIVKVAEEPDAPIV
IHAVQHVMHPPARLPAWPDEDHRTRLVMIVRDLDPKVIARLFNAFLGVPQVDTPDRAALTDNPLAPPGLR

Sequences:

>Translated_390_residues
MPGNVPAPEAPAQNAPADTAPARRRGPPEPIPVTVLTGFLGAGKTTLLNALLADPGLADTAVLINEFGEVGLDHLFVRPV
EEGIVMLASGCLCCTVRGDLVAALEDLLRGRDNDRLPPFARVIIETTGLADPAPVIHTLMTHPYLGLRYRLDGLVCVVDA
VNADATLDAHEEAVKQAAMADRIVLTKTDLVADADRPQLEALRARLKSLAPGARLLDAAAGEAQAASILGAGLYATAGKA
PDVARWLAAEEVAAAEPDGASLDPNRHDARIRAFTLATDAAIPAATLDLFLELLRATHGGNVLRMKGIVKVAEEPDAPIV
IHAVQHVMHPPARLPAWPDEDHRTRLVMIVRDLDPKVIARLFNAFLGVPQVDTPDRAALTDNPLAPPGLR
>Mature_389_residues
PGNVPAPEAPAQNAPADTAPARRRGPPEPIPVTVLTGFLGAGKTTLLNALLADPGLADTAVLINEFGEVGLDHLFVRPVE
EGIVMLASGCLCCTVRGDLVAALEDLLRGRDNDRLPPFARVIIETTGLADPAPVIHTLMTHPYLGLRYRLDGLVCVVDAV
NADATLDAHEEAVKQAAMADRIVLTKTDLVADADRPQLEALRARLKSLAPGARLLDAAAGEAQAASILGAGLYATAGKAP
DVARWLAAEEVAAAEPDGASLDPNRHDARIRAFTLATDAAIPAATLDLFLELLRATHGGNVLRMKGIVKVAEEPDAPIVI
HAVQHVMHPPARLPAWPDEDHRTRLVMIVRDLDPKVIARLFNAFLGVPQVDTPDRAALTDNPLAPPGLR

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=372, Percent_Identity=28.494623655914, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI126722884, Length=370, Percent_Identity=28.1081081081081, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI223941779, Length=370, Percent_Identity=29.1891891891892, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI148727351, Length=370, Percent_Identity=28.1081081081081, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI146231952, Length=370, Percent_Identity=28.3783783783784, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI223941776, Length=344, Percent_Identity=27.6162790697674, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI119120938, Length=149, Percent_Identity=35.5704697986577, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI87082430, Length=320, Percent_Identity=34.375, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1788499, Length=163, Percent_Identity=36.1963190184049, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324356, Length=213, Percent_Identity=29.5774647887324, Blast_Score=93, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 41219; Mature: 41088

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGNVPAPEAPAQNAPADTAPARRRGPPEPIPVTVLTGFLGAGKTTLLNALLADPGLADT
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHH
AVLINEFGEVGLDHLFVRPVEEGIVMLASGCLCCTVRGDLVAALEDLLRGRDNDRLPPFA
HHHHHHHHHHCHHHHHHCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCCCCCHHH
RVIIETTGLADPAPVIHTLMTHPYLGLRYRLDGLVCVVDAVNADATLDAHEEAVKQAAMA
HHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHH
DRIVLTKTDLVADADRPQLEALRARLKSLAPGARLLDAAAGEAQAASILGAGLYATAGKA
CCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCHHHCCCCC
PDVARWLAAEEVAAAEPDGASLDPNRHDARIRAFTLATDAAIPAATLDLFLELLRATHGG
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCC
NVLRMKGIVKVAEEPDAPIVIHAVQHVMHPPARLPAWPDEDHRTRLVMIVRDLDPKVIAR
CEEEEHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHH
LFNAFLGVPQVDTPDRAALTDNPLAPPGLR
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PGNVPAPEAPAQNAPADTAPARRRGPPEPIPVTVLTGFLGAGKTTLLNALLADPGLADT
CCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHH
AVLINEFGEVGLDHLFVRPVEEGIVMLASGCLCCTVRGDLVAALEDLLRGRDNDRLPPFA
HHHHHHHHHHCHHHHHHCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCCCCCHHH
RVIIETTGLADPAPVIHTLMTHPYLGLRYRLDGLVCVVDAVNADATLDAHEEAVKQAAMA
HHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHH
DRIVLTKTDLVADADRPQLEALRARLKSLAPGARLLDAAAGEAQAASILGAGLYATAGKA
CCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCHHHCCCCC
PDVARWLAAEEVAAAEPDGASLDPNRHDARIRAFTLATDAAIPAATLDLFLELLRATHGG
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCC
NVLRMKGIVKVAEEPDAPIVIHAVQHVMHPPARLPAWPDEDHRTRLVMIVRDLDPKVIAR
CEEEEHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHH
LFNAFLGVPQVDTPDRAALTDNPLAPPGLR
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]