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The map label for this gene is clpB [H]

Identifier: 154245846

GI number: 154245846

Start: 2143124

End: 2145763

Strand: Direct

Name: clpB [H]

Synonym: Xaut_1902

Alternate gene names: 154245846

Gene position: 2143124-2145763 (Clockwise)

Preceding gene: 154245839

Following gene: 154245847

Centisome position: 40.37

GC content: 67.12

Gene sequence:

>2640_bases
ATGAATTTTGAGATCTATACCGAGCGCGCGCGCGGCTTCGTCCAGTCGGCCCAGTCGCTGGCGACCCGGGAGGGTAACCA
GCAGTTCACGCCCGAGCACCTGCTCAAGGTGCTGATGGACGATCCCGAAGGCCTGTGCTCGGGCCTGATCCAGCGCGCGG
GCGGCAATCTCGTGCTGGTGCGGGCCGAGGTCGAAGCGGCGCTGAAGAAGCTGCCGAAGGTGGAAGGCGGCTCCGGCCAG
GTCTATCTCAGCCAGCAGCTGGCCAAGGTGTTCGAGACCGCCGAGCAGGCGGCCAAGAAGGCGGGCGACGGCTATGTCAC
CGTCGAGCGGATGCTGCTCGCCCTGACCATCGAGAAGGACACCGAGGCGGGCCGCATCCTGGTGAAGGCCGGCGTGACGC
CGCAGACCCTGAATGCGGCCATCGAGGCCCTGCGCAAGGGCCGCACTGCGGACAGCGCTACCGCCGAGAATGCCTATGAC
GCCCTGAAGAAATACGCCCGCGACCTCACCCAGGCCGTGCGGGACGGCAAGCTCGACCCGGTCATTGGCCGCGACGAGGA
GATCCGCCGCACCATCCAGGTGCTGGCGCGCCGCACCAAGAACAATCCCGTGCTCATCGGCGAGCCCGGTGTCGGCAAGA
CCGCCATCGTGGAGGGCCTTGCCCGCCGCATCGTGGACGGCGACGTGCCGGAGAGCCTGAAGAACAAGAGCCTGCTGGCC
CTCGACATGGGCTCCCTCATCGCCGGCGCGAAATATCGCGGCGAGTTCGAGGAGCGCCTGAAGAGCGTGCTCTCCGAGGT
GGAGAGCGCGGAAGGCGGCATCATCCTGTTCATCGACGAGATGCACACCCTGGTCGGCGCCGGCAAGACCGACGGCGCCA
TGGATGCCTCCAACCTCTTGAAGCCGGCGCTGGCCCGCGGCGAGCTGCACTGCGTCGGCGCGACCACGCTGGATGAATAT
CGCAAGCACGTGGAGAAGGACGCAGCCCTGGCCCGTCGCTTCCAGCCCGTCTTCGTCTCCGAGCCCACGGTGGAGGATAC
CGTCTCCATCCTGCGCGGGCTGAAGGAGAAGTACGAGCTGCACCACGGCGTGCGCATCACCGATTCGGCGCTGGTGTCGG
CGGCGGTCCTGTCCAACCGCTACATCACCGACCGCTTCCTGCCCGACAAGGCCATCGACCTGATGGACGAGGCGGCTTCC
CGCCTGCGCATGCAGGTGGATTCGAAGCCCGAGGAGCTGGACAGTCTCGATCGCGAGATCATGCGCCGCAAGATCGAGCA
GGAGGCCCTCAAGAAGGAGACCGACACCGCCTCCAAGGACCGCCTGAAGCGGTCCGAGAAGGAGTTGGCCGACCTTGAGG
AGAAGGCTTCCGTCCTCACCTCCAAGTGGAAGGCGGAGAAGGAGAAGCTGGGCGCCGCGACCACGCTGAAGTCGAAGCTC
GACCAGGCGCGGGCGGATCTGGCCACCGCGCAGCGGCAGGGCGAATACCAGAAGGCCGGCGAGCTGACCTATTCGGTCAT
CCCCGAGCTTGAGAAGAAGCTCGCCGAGGTCGAGAAGGCGGGCGCAGCCGGGCAGATGGTGGAAGAGGCGGTGACGCCGA
ACCACATCGCCGGCGTCGTCTCGCGCTGGACCGGCGTGCCGGTGGACAAGATGCTGGAAGGCGAGCGCGAGAAGCTCTTG
CGCATGGAGCTGGAGCTGGCCAAGCGCGTGGTGGGCCAGTCGGAGGCGGTGGCCGCCGTCTCCACTGCCGTGCGTCGCGC
CCGCGCCGGCCTCCAGGACCCGAACCGGCCCATCGGCTCGTTCCTGTTCCTCGGCCCCACCGGCGTCGGCAAGACCGAGC
TGACCAAGGCGCTCGCCGAATTCCTGTTCGACGACGAGACCGCCATGGTCCGCATCGACATGTCGGAATACATGGAGAAG
CACTCCGTGAGCCGCCTCATCGGCGCGCCTCCCGGCTATGTGGGCTATGACGAGGGCGGTGCCCTCACCGAGGCGGTCCG
CCGCCGGCCCTACCAGGTGGTGCTGTTCGACGAGGTGGAGAAGGCCCATCCGGACGTGTTCAATGTCCTCCTGCAGGTGC
TCGACGACGGGCGCCTCACGGACGGGCAGGGGCGCACGGTGGACTTCCGCAATGTGCTTATCGTCATGACCTCCAACCTC
GGCGCCGAATTCCTCGCCGACCCGCGCCAGCCCATGGGCTTCAAGGTGCCGGGCCACGAGGGAGAGACCGTGGTGTCGGA
CGAGGAGGCCTACGATATGGTGATGGGGGCGGTGCGGCGTCATTTCCGCCCCGAATTCATCAACCGCATCGACGAGATCG
TCATGTTCCACCGCCTGAAGCGGGAGCAGATGGACTCCATCGTGGACATCCAGATGGGCCGGCTGCGCAAGCTGCTGGAG
GATCGCAAGATCACCATCGAGCTGTCCCCCGAGGCGCGGGCCTTCCTCGCCGAGAAGGGTTACGACCCGGCCTATGGCGC
GCGTCCCCTGAAGCGCACCATCCAGAAGCTGGTGCAGGACCCGCTGGCCGAGAAGATCCTCGCCGGCACCGTCCTGGACG
GCGCAACGGTGAAGGTGGGCCTGGACAACGGCCAGCTTACCTTCGCGGGAGAGGCGGCGCCGGTGGACCAGGCCGCCTGA

Upstream 100 bases:

>100_bases
CGTTCCATCTGTGCAGCGGTAGCCGGGGATGCCGGGACCGTGTCCCACCGTGCCCCCTATGCTTCCTGAGAAGGTACCGG
GCGCGAGAAGGAGGAGAGAC

Downstream 100 bases:

>100_bases
GGACGGTCCGGTCCCGAGCGGCTGAGAACAGAAAGGCCCTCCCCATCGGGAGGGCCTTTTTCATGTCTCCCGCAAGGTCT
ATGGCGTCCGCGCCGGACCG

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 879; Mature: 879

Protein sequence:

>879_residues
MNFEIYTERARGFVQSAQSLATREGNQQFTPEHLLKVLMDDPEGLCSGLIQRAGGNLVLVRAEVEAALKKLPKVEGGSGQ
VYLSQQLAKVFETAEQAAKKAGDGYVTVERMLLALTIEKDTEAGRILVKAGVTPQTLNAAIEALRKGRTADSATAENAYD
ALKKYARDLTQAVRDGKLDPVIGRDEEIRRTIQVLARRTKNNPVLIGEPGVGKTAIVEGLARRIVDGDVPESLKNKSLLA
LDMGSLIAGAKYRGEFEERLKSVLSEVESAEGGIILFIDEMHTLVGAGKTDGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDAALARRFQPVFVSEPTVEDTVSILRGLKEKYELHHGVRITDSALVSAAVLSNRYITDRFLPDKAIDLMDEAAS
RLRMQVDSKPEELDSLDREIMRRKIEQEALKKETDTASKDRLKRSEKELADLEEKASVLTSKWKAEKEKLGAATTLKSKL
DQARADLATAQRQGEYQKAGELTYSVIPELEKKLAEVEKAGAAGQMVEEAVTPNHIAGVVSRWTGVPVDKMLEGEREKLL
RMELELAKRVVGQSEAVAAVSTAVRRARAGLQDPNRPIGSFLFLGPTGVGKTELTKALAEFLFDDETAMVRIDMSEYMEK
HSVSRLIGAPPGYVGYDEGGALTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNVLIVMTSNL
GAEFLADPRQPMGFKVPGHEGETVVSDEEAYDMVMGAVRRHFRPEFINRIDEIVMFHRLKREQMDSIVDIQMGRLRKLLE
DRKITIELSPEARAFLAEKGYDPAYGARPLKRTIQKLVQDPLAEKILAGTVLDGATVKVGLDNGQLTFAGEAAPVDQAA

Sequences:

>Translated_879_residues
MNFEIYTERARGFVQSAQSLATREGNQQFTPEHLLKVLMDDPEGLCSGLIQRAGGNLVLVRAEVEAALKKLPKVEGGSGQ
VYLSQQLAKVFETAEQAAKKAGDGYVTVERMLLALTIEKDTEAGRILVKAGVTPQTLNAAIEALRKGRTADSATAENAYD
ALKKYARDLTQAVRDGKLDPVIGRDEEIRRTIQVLARRTKNNPVLIGEPGVGKTAIVEGLARRIVDGDVPESLKNKSLLA
LDMGSLIAGAKYRGEFEERLKSVLSEVESAEGGIILFIDEMHTLVGAGKTDGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDAALARRFQPVFVSEPTVEDTVSILRGLKEKYELHHGVRITDSALVSAAVLSNRYITDRFLPDKAIDLMDEAAS
RLRMQVDSKPEELDSLDREIMRRKIEQEALKKETDTASKDRLKRSEKELADLEEKASVLTSKWKAEKEKLGAATTLKSKL
DQARADLATAQRQGEYQKAGELTYSVIPELEKKLAEVEKAGAAGQMVEEAVTPNHIAGVVSRWTGVPVDKMLEGEREKLL
RMELELAKRVVGQSEAVAAVSTAVRRARAGLQDPNRPIGSFLFLGPTGVGKTELTKALAEFLFDDETAMVRIDMSEYMEK
HSVSRLIGAPPGYVGYDEGGALTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNVLIVMTSNL
GAEFLADPRQPMGFKVPGHEGETVVSDEEAYDMVMGAVRRHFRPEFINRIDEIVMFHRLKREQMDSIVDIQMGRLRKLLE
DRKITIELSPEARAFLAEKGYDPAYGARPLKRTIQKLVQDPLAEKILAGTVLDGATVKVGLDNGQLTFAGEAAPVDQAA
>Mature_879_residues
MNFEIYTERARGFVQSAQSLATREGNQQFTPEHLLKVLMDDPEGLCSGLIQRAGGNLVLVRAEVEAALKKLPKVEGGSGQ
VYLSQQLAKVFETAEQAAKKAGDGYVTVERMLLALTIEKDTEAGRILVKAGVTPQTLNAAIEALRKGRTADSATAENAYD
ALKKYARDLTQAVRDGKLDPVIGRDEEIRRTIQVLARRTKNNPVLIGEPGVGKTAIVEGLARRIVDGDVPESLKNKSLLA
LDMGSLIAGAKYRGEFEERLKSVLSEVESAEGGIILFIDEMHTLVGAGKTDGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDAALARRFQPVFVSEPTVEDTVSILRGLKEKYELHHGVRITDSALVSAAVLSNRYITDRFLPDKAIDLMDEAAS
RLRMQVDSKPEELDSLDREIMRRKIEQEALKKETDTASKDRLKRSEKELADLEEKASVLTSKWKAEKEKLGAATTLKSKL
DQARADLATAQRQGEYQKAGELTYSVIPELEKKLAEVEKAGAAGQMVEEAVTPNHIAGVVSRWTGVPVDKMLEGEREKLL
RMELELAKRVVGQSEAVAAVSTAVRRARAGLQDPNRPIGSFLFLGPTGVGKTELTKALAEFLFDDETAMVRIDMSEYMEK
HSVSRLIGAPPGYVGYDEGGALTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNVLIVMTSNL
GAEFLADPRQPMGFKVPGHEGETVVSDEEAYDMVMGAVRRHFRPEFINRIDEIVMFHRLKREQMDSIVDIQMGRLRKLLE
DRKITIELSPEARAFLAEKGYDPAYGARPLKRTIQKLVQDPLAEKILAGTVLDGATVKVGLDNGQLTFAGEAAPVDQAA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=357, Percent_Identity=34.453781512605, Blast_Score=207, Evalue=3e-53,
Organism=Escherichia coli, GI1788943, Length=860, Percent_Identity=59.3023255813954, Blast_Score=1010, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=370, Percent_Identity=42.7027027027027, Blast_Score=296, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6320464, Length=708, Percent_Identity=57.4858757062147, Blast_Score=815, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=877, Percent_Identity=45.0399087799316, Blast_Score=724, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96714; Mature: 96714

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFEIYTERARGFVQSAQSLATREGNQQFTPEHLLKVLMDDPEGLCSGLIQRAGGNLVLV
CCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEE
RAEVEAALKKLPKVEGGSGQVYLSQQLAKVFETAEQAAKKAGDGYVTVERMLLALTIEKD
EHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCC
TEAGRILVKAGVTPQTLNAAIEALRKGRTADSATAENAYDALKKYARDLTQAVRDGKLDP
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIGRDEEIRRTIQVLARRTKNNPVLIGEPGVGKTAIVEGLARRIVDGDVPESLKNKSLLA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEE
LDMGSLIAGAKYRGEFEERLKSVLSEVESAEGGIILFIDEMHTLVGAGKTDGAMDASNLL
EEHHHHHHCCHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHH
KPALARGELHCVGATTLDEYRKHVEKDAALARRFQPVFVSEPTVEDTVSILRGLKEKYEL
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHGVRITDSALVSAAVLSNRYITDRFLPDKAIDLMDEAASRLRMQVDSKPEELDSLDREI
HCCCEECHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MRRKIEQEALKKETDTASKDRLKRSEKELADLEEKASVLTSKWKAEKEKLGAATTLKSKL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
DQARADLATAQRQGEYQKAGELTYSVIPELEKKLAEVEKAGAAGQMVEEAVTPNHIAGVV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHH
SRWTGVPVDKMLEGEREKLLRMELELAKRVVGQSEAVAAVSTAVRRARAGLQDPNRPIGS
HHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
FLFLGPTGVGKTELTKALAEFLFDDETAMVRIDMSEYMEKHSVSRLIGAPPGYVGYDEGG
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
ALTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNVLIVMTSNL
HHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEECCC
GAEFLADPRQPMGFKVPGHEGETVVSDEEAYDMVMGAVRRHFRPEFINRIDEIVMFHRLK
CHHHHCCCCCCCCEECCCCCCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
REQMDSIVDIQMGRLRKLLEDRKITIELSPEARAFLAEKGYDPAYGARPLKRTIQKLVQD
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
PLAEKILAGTVLDGATVKVGLDNGQLTFAGEAAPVDQAA
HHHHHHHHHHEECCCEEEEECCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MNFEIYTERARGFVQSAQSLATREGNQQFTPEHLLKVLMDDPEGLCSGLIQRAGGNLVLV
CCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEE
RAEVEAALKKLPKVEGGSGQVYLSQQLAKVFETAEQAAKKAGDGYVTVERMLLALTIEKD
EHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCC
TEAGRILVKAGVTPQTLNAAIEALRKGRTADSATAENAYDALKKYARDLTQAVRDGKLDP
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIGRDEEIRRTIQVLARRTKNNPVLIGEPGVGKTAIVEGLARRIVDGDVPESLKNKSLLA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEE
LDMGSLIAGAKYRGEFEERLKSVLSEVESAEGGIILFIDEMHTLVGAGKTDGAMDASNLL
EEHHHHHHCCHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHH
KPALARGELHCVGATTLDEYRKHVEKDAALARRFQPVFVSEPTVEDTVSILRGLKEKYEL
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHGVRITDSALVSAAVLSNRYITDRFLPDKAIDLMDEAASRLRMQVDSKPEELDSLDREI
HCCCEECHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MRRKIEQEALKKETDTASKDRLKRSEKELADLEEKASVLTSKWKAEKEKLGAATTLKSKL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
DQARADLATAQRQGEYQKAGELTYSVIPELEKKLAEVEKAGAAGQMVEEAVTPNHIAGVV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHH
SRWTGVPVDKMLEGEREKLLRMELELAKRVVGQSEAVAAVSTAVRRARAGLQDPNRPIGS
HHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
FLFLGPTGVGKTELTKALAEFLFDDETAMVRIDMSEYMEKHSVSRLIGAPPGYVGYDEGG
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
ALTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNVLIVMTSNL
HHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEECCC
GAEFLADPRQPMGFKVPGHEGETVVSDEEAYDMVMGAVRRHFRPEFINRIDEIVMFHRLK
CHHHHCCCCCCCCEECCCCCCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
REQMDSIVDIQMGRLRKLLEDRKITIELSPEARAFLAEKGYDPAYGARPLKRTIQKLVQD
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
PLAEKILAGTVLDGATVKVGLDNGQLTFAGEAAPVDQAA
HHHHHHHHHHEECCCEEEEECCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA