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The map label for this gene is paaK [H]

Identifier: 154245810

GI number: 154245810

Start: 2102193

End: 2103515

Strand: Direct

Name: paaK [H]

Synonym: Xaut_1866

Alternate gene names: 154245810

Gene position: 2102193-2103515 (Clockwise)

Preceding gene: 154245809

Following gene: 154245815

Centisome position: 39.6

GC content: 68.93

Gene sequence:

>1323_bases
ATGGCCCCCTCTCCCGCTTGCAGGGGTGGGCTGGGGAGGGGGAAGGGGCGTCCGGATTCTGGCAATAGAGACTGTCACAT
GACCGATCCGAACCGCCATTACGATGCGTGCGAGACCCGCGATCCCGAAGCCCGTGAACAGGCACTGATGGCGGCGCTTG
CCGCCCAGGTCGCTCACGCCAAGGCGAAGGCGCCCTATTTCGCGCGCCTCTTCAAGGACGTGGACCCGCAGGCGGTGACC
ACCCGCGCGGCGCTGGCGAAGCTCCCCGTCACCCGCAAGTCGGACCTTTTGGAGATCCAGCCGAAGAGCTATCCCTTCGG
CGGCCTCAATGCGACGGCGCCGGGCAAGCTGGCGCGCATCTTCATGTCGCCGGGGCCGATCTATGATCCGGAAGGCCATG
GCGCCGACTTCTGGCGCTTCGCCCGCGGCCTGTTCGCGGCCGGCTTCCGGGCCGGCGACATCGTCCACAACTGCTTTTCC
TATCACCTCACCCCGGCCGGCTCGATGATCGAGAGCGGCGCCCATGCGCTCGGCTGCGCGGTGGTTCCGGCGGGGGTCGG
CCAGACCGACCTGCAATTGCGCGCCATCGCCGACATCCGACCCCAGGGCTATGGCGGCACGCCGTCCTTCCTGAAGATCC
TGGTGGACAAGGCGCGGGAGACCGGCACCGACATTTCCTCCCTCAAGAAGGCTCTGGTGACGGGGGAAGCCTTCCTGCCC
GCCCATCGCGCCGAGCTGAAGGCCGCGGGCATTGCCGCCCGGCAGTGCTATGGCTCCGCCGACCTCGGCCTCGTCGCTTA
CGAGAGCGAGGCGGAAGAGGGCATGATCGTGGACGAGGGCTGCCTCGTGGAAATCCTGCGCCCCGGCACCGGCGATCCGG
TGGAAGCCGATGGTGAGGTCGGCGAGGTGGTCGTCACCCTGTTCGAGCCCGACTATCCCCTGGTGCGTTTCGCCACCGGC
GATCTTTCGGCGGTGCTGCCGGGCTTCAGCCCCTGCGGGCGCACCAACGTCCGCCTCAAGGGCTGGATGGGCCGCGCCGA
CCAGGTGACCAAGATCCGCGGCATGTTCGTGCACCCGGTGCAGGTGAGCGCGGCGGTGAAGAAGCATCCGGCGGTGGCGA
AGGCCCGCCTCGTGGTGGATCGCATCGGCGATGCCGACGACATGCTGCTGGAGGTGGAAGTTCAGGACGCCGCAGCGCTG
TCGCAGGAGGCGCTGCTGGACGACCTGCGCGCCACCACCAAGCTGCGCGGCCGCGTGGCCCTGCTGGTGCCGGGTACGCT
GCCGGCTGACGCCAAGACCATCGAGGACCGCCGGCCGGTGTGA

Upstream 100 bases:

>100_bases
CCGCAAACGGTGGTTGTGACGGCTTGAACATGGCTTTCGGCTCCGCCCCCTCCCAACCCTCGCCCGCGAGCGGGAGAGGG
CTTTTCCCGCTCTCTCCGCC

Downstream 100 bases:

>100_bases
GGCCGGTGCGGCGCCGGTAACGACTCAGCGTGGGTTTGAGAACTCTCCCGGTTGGACGCTGTCAGCTCTCACTGACGCTT
AATTGCCTGCTTCAAGCGGT

Product: coenzyme F390 synthetase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MAPSPACRGGLGRGKGRPDSGNRDCHMTDPNRHYDACETRDPEAREQALMAALAAQVAHAKAKAPYFARLFKDVDPQAVT
TRAALAKLPVTRKSDLLEIQPKSYPFGGLNATAPGKLARIFMSPGPIYDPEGHGADFWRFARGLFAAGFRAGDIVHNCFS
YHLTPAGSMIESGAHALGCAVVPAGVGQTDLQLRAIADIRPQGYGGTPSFLKILVDKARETGTDISSLKKALVTGEAFLP
AHRAELKAAGIAARQCYGSADLGLVAYESEAEEGMIVDEGCLVEILRPGTGDPVEADGEVGEVVVTLFEPDYPLVRFATG
DLSAVLPGFSPCGRTNVRLKGWMGRADQVTKIRGMFVHPVQVSAAVKKHPAVAKARLVVDRIGDADDMLLEVEVQDAAAL
SQEALLDDLRATTKLRGRVALLVPGTLPADAKTIEDRRPV

Sequences:

>Translated_440_residues
MAPSPACRGGLGRGKGRPDSGNRDCHMTDPNRHYDACETRDPEAREQALMAALAAQVAHAKAKAPYFARLFKDVDPQAVT
TRAALAKLPVTRKSDLLEIQPKSYPFGGLNATAPGKLARIFMSPGPIYDPEGHGADFWRFARGLFAAGFRAGDIVHNCFS
YHLTPAGSMIESGAHALGCAVVPAGVGQTDLQLRAIADIRPQGYGGTPSFLKILVDKARETGTDISSLKKALVTGEAFLP
AHRAELKAAGIAARQCYGSADLGLVAYESEAEEGMIVDEGCLVEILRPGTGDPVEADGEVGEVVVTLFEPDYPLVRFATG
DLSAVLPGFSPCGRTNVRLKGWMGRADQVTKIRGMFVHPVQVSAAVKKHPAVAKARLVVDRIGDADDMLLEVEVQDAAAL
SQEALLDDLRATTKLRGRVALLVPGTLPADAKTIEDRRPV
>Mature_439_residues
APSPACRGGLGRGKGRPDSGNRDCHMTDPNRHYDACETRDPEAREQALMAALAAQVAHAKAKAPYFARLFKDVDPQAVTT
RAALAKLPVTRKSDLLEIQPKSYPFGGLNATAPGKLARIFMSPGPIYDPEGHGADFWRFARGLFAAGFRAGDIVHNCFSY
HLTPAGSMIESGAHALGCAVVPAGVGQTDLQLRAIADIRPQGYGGTPSFLKILVDKARETGTDISSLKKALVTGEAFLPA
HRAELKAAGIAARQCYGSADLGLVAYESEAEEGMIVDEGCLVEILRPGTGDPVEADGEVGEVVVTLFEPDYPLVRFATGD
LSAVLPGFSPCGRTNVRLKGWMGRADQVTKIRGMFVHPVQVSAAVKKHPAVAKARLVVDRIGDADDMLLEVEVQDAAALS
QEALLDDLRATTKLRGRVALLVPGTLPADAKTIEDRRPV

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=413, Percent_Identity=30.2663438256659, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 46807; Mature: 46676

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSPACRGGLGRGKGRPDSGNRDCHMTDPNRHYDACETRDPEAREQALMAALAAQVAHA
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KAKAPYFARLFKDVDPQAVTTRAALAKLPVTRKSDLLEIQPKSYPFGGLNATAPGKLARI
HHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEE
FMSPGPIYDPEGHGADFWRFARGLFAAGFRAGDIVHNCFSYHLTPAGSMIESGAHALGCA
EECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHCCCHHEEEE
VVPAGVGQTDLQLRAIADIRPQGYGGTPSFLKILVDKARETGTDISSLKKALVTGEAFLP
EECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHCC
AHRAELKAAGIAARQCYGSADLGLVAYESEAEEGMIVDEGCLVEILRPGTGDPVEADGEV
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCEEEEECCCCCCCCCCCCCC
GEVVVTLFEPDYPLVRFATGDLSAVLPGFSPCGRTNVRLKGWMGRADQVTKIRGMFVHPV
CEEEEEEECCCCCEEEEECCCHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHCCEEECCC
QVSAAVKKHPAVAKARLVVDRIGDADDMLLEVEVQDAAALSQEALLDDLRATTKLRGRVA
HHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEE
LLVPGTLPADAKTIEDRRPV
EEECCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
APSPACRGGLGRGKGRPDSGNRDCHMTDPNRHYDACETRDPEAREQALMAALAAQVAHA
CCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KAKAPYFARLFKDVDPQAVTTRAALAKLPVTRKSDLLEIQPKSYPFGGLNATAPGKLARI
HHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEE
FMSPGPIYDPEGHGADFWRFARGLFAAGFRAGDIVHNCFSYHLTPAGSMIESGAHALGCA
EECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHCCCHHEEEE
VVPAGVGQTDLQLRAIADIRPQGYGGTPSFLKILVDKARETGTDISSLKKALVTGEAFLP
EECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHCC
AHRAELKAAGIAARQCYGSADLGLVAYESEAEEGMIVDEGCLVEILRPGTGDPVEADGEV
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCEEEEECCCCCCCCCCCCCC
GEVVVTLFEPDYPLVRFATGDLSAVLPGFSPCGRTNVRLKGWMGRADQVTKIRGMFVHPV
CEEEEEEECCCCCEEEEECCCHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHCCEEECCC
QVSAAVKKHPAVAKARLVVDRIGDADDMLLEVEVQDAAALSQEALLDDLRATTKLRGRVA
HHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEE
LLVPGTLPADAKTIEDRRPV
EEECCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]