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The map label for this gene is selA [H]

Identifier: 154244609

GI number: 154244609

Start: 739710

End: 741167

Strand: Reverse

Name: selA [H]

Synonym: Xaut_0658

Alternate gene names: 154244609

Gene position: 741167-739710 (Counterclockwise)

Preceding gene: 154244610

Following gene: 154244608

Centisome position: 13.96

GC content: 71.4

Gene sequence:

>1458_bases
ATGTCCGCACATCCTGCATCATTCCCCGCCGCCCCACCCCCGGTCGCCCCACCCCCTGTCGCCCCGCTGCGGGTGCTGCC
CTCCGTCGATGCCGTACTGAAGGTTGAGCTGGCCCGCGCCGCCACCGAGCGCCACGGCCGGCAGGCGACCACCGCGGCCG
TGCGCACCGCCCTCGACGAACGCCGCGCCGCCCTGCGCGCCGGTGCCGGCGGTGCGGCGACGCCCGAGGAGATCGCGGCC
AGCGCCCTCGCCCGGCTGGATGCGGCGGCGGCCCCCAGCCTCCGTCCGGTGTTCAACCTCACCGGCACCGTTCTGCACAC
CAATCTCGGCCGCGCCATCTTCGCGGAAGAGGCGGTGGAAGCGGCAGTACGGGCCATGCGAAGCGCGGTCGCGCTGGAAT
ACGACCTCGACGGCGGCAAGCGCGGCGAGCGCGACGACCATGTGCGCGGCCTCGTCTGCGAGCTGACCGGGGCGGAGGAC
GCCACCCTCGTCAACAACAATGCCGCCGCCGTGCTCCTCGTGCTGAACACCCTGTCGCAGGGCAAGCCGGCCATCGTCTC
GCGCGGCGAGCTGATCGAGATCGGCGGTGCCTTCCGCATGCCGGAGATCATGCGCCGGGCCGGCGCCGAGCTGGACGAGG
TGGGCACCACCAACCGCACCCATGCCCGCGATTATCGCGACGCCATCCGCCCCGAGACCGGGGTGATCCTGAAGGTGCAT
ACCTCCAACTACCGCATCGAGGGCTTCACCAAGGAGGTCTCGCCCCGCGAGCTGGCCGAGATCGCGCAGGCCGGCGGGGT
GCCCCTCGTCAATGATCTGGGCTCCGGCACGCTGGCGGATCTGGCCCGCTACGGCCTCGTCCACGAGCCGACCGTGCGGG
AGGCGGTGGCCGAGGGAGCCGACGTGGTCACCTTCTCCGGCGACAAGCTGCTGGGAGGCCCGCAGGCCGGTTTCATCGTG
GGCCGGCGCGACCTCATCGCCCGAATCAACAAGAACCCCATGAAGCGGGCGCTGCGGCTGGACAAGGTGCGCCTCGCCGC
CGTCGAGGCGACGCTGCGCCTGTACCGCGACCCGGACCGCCTCGCCGCGCGCCTGCCCACCCTGCGCTATCTCACCCGCC
GGCCGGAGGACATGGCTGCCCAGGCCGCGCGGCTGAAGCCCGCCCTCGCCGCGATCCTTGGACCCGCCTTCACAATTGAC
GCAACGGCATGCCGCAGCCAGATCGGCTCTGGCGCCCTGCCGCTGGAGACACTGGAGGGCGTCGGCCTTGCCATCGCCAG
CCGCGACGGCAGCGGCGGCGCGCTCAACCGGCTGGCCGATGGGCTGCGCCGACTTCCGGTTCCGGTCATCGGACGGATTG
ACGATAACGCTCTTGTGCTCGATTTGAGATGCCTTGAAGACGAAGCGGCGTTTCTCGCGTCCGTGACCGCTTTGGAGGGG
GCTCATGAGCTGGCTTGA

Upstream 100 bases:

>100_bases
CGACGACGTGGCCAGCCTCGGCCTCGACCTCAAGCAGAAGGAGGGGCCCTACCGGCGCGCCACCTTCAACCCCTTCCTGC
TGGGCTATTGAGGGGGCGCC

Downstream 100 bases:

>100_bases
CCGACTGAAGGGCAAGGGGGGTCCGGGCGAGACGCCAGGTGCCGAAGATCCACCGCGCGTGCGCCCCTTCCCGCAACGCC
CCCAGCGCCCCACCGAGGAG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MSAHPASFPAAPPPVAPPPVAPLRVLPSVDAVLKVELARAATERHGRQATTAAVRTALDERRAALRAGAGGAATPEEIAA
SALARLDAAAAPSLRPVFNLTGTVLHTNLGRAIFAEEAVEAAVRAMRSAVALEYDLDGGKRGERDDHVRGLVCELTGAED
ATLVNNNAAAVLLVLNTLSQGKPAIVSRGELIEIGGAFRMPEIMRRAGAELDEVGTTNRTHARDYRDAIRPETGVILKVH
TSNYRIEGFTKEVSPRELAEIAQAGGVPLVNDLGSGTLADLARYGLVHEPTVREAVAEGADVVTFSGDKLLGGPQAGFIV
GRRDLIARINKNPMKRALRLDKVRLAAVEATLRLYRDPDRLAARLPTLRYLTRRPEDMAAQAARLKPALAAILGPAFTID
ATACRSQIGSGALPLETLEGVGLAIASRDGSGGALNRLADGLRRLPVPVIGRIDDNALVLDLRCLEDEAAFLASVTALEG
AHELA

Sequences:

>Translated_485_residues
MSAHPASFPAAPPPVAPPPVAPLRVLPSVDAVLKVELARAATERHGRQATTAAVRTALDERRAALRAGAGGAATPEEIAA
SALARLDAAAAPSLRPVFNLTGTVLHTNLGRAIFAEEAVEAAVRAMRSAVALEYDLDGGKRGERDDHVRGLVCELTGAED
ATLVNNNAAAVLLVLNTLSQGKPAIVSRGELIEIGGAFRMPEIMRRAGAELDEVGTTNRTHARDYRDAIRPETGVILKVH
TSNYRIEGFTKEVSPRELAEIAQAGGVPLVNDLGSGTLADLARYGLVHEPTVREAVAEGADVVTFSGDKLLGGPQAGFIV
GRRDLIARINKNPMKRALRLDKVRLAAVEATLRLYRDPDRLAARLPTLRYLTRRPEDMAAQAARLKPALAAILGPAFTID
ATACRSQIGSGALPLETLEGVGLAIASRDGSGGALNRLADGLRRLPVPVIGRIDDNALVLDLRCLEDEAAFLASVTALEG
AHELA
>Mature_484_residues
SAHPASFPAAPPPVAPPPVAPLRVLPSVDAVLKVELARAATERHGRQATTAAVRTALDERRAALRAGAGGAATPEEIAAS
ALARLDAAAAPSLRPVFNLTGTVLHTNLGRAIFAEEAVEAAVRAMRSAVALEYDLDGGKRGERDDHVRGLVCELTGAEDA
TLVNNNAAAVLLVLNTLSQGKPAIVSRGELIEIGGAFRMPEIMRRAGAELDEVGTTNRTHARDYRDAIRPETGVILKVHT
SNYRIEGFTKEVSPRELAEIAQAGGVPLVNDLGSGTLADLARYGLVHEPTVREAVAEGADVVTFSGDKLLGGPQAGFIVG
RRDLIARINKNPMKRALRLDKVRLAAVEATLRLYRDPDRLAARLPTLRYLTRRPEDMAAQAARLKPALAAILGPAFTIDA
TACRSQIGSGALPLETLEGVGLAIASRDGSGGALNRLADGLRRLPVPVIGRIDDNALVLDLRCLEDEAAFLASVTALEGA
HELA

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=447, Percent_Identity=54.3624161073826, Blast_Score=437, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 51086; Mature: 50955

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHPASFPAAPPPVAPPPVAPLRVLPSVDAVLKVELARAATERHGRQATTAAVRTALDE
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RRAALRAGAGGAATPEEIAASALARLDAAAAPSLRPVFNLTGTVLHTNLGRAIFAEEAVE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCHHHHHHHHHH
AAVRAMRSAVALEYDLDGGKRGERDDHVRGLVCELTGAEDATLVNNNAAAVLLVLNTLSQ
HHHHHHHHHHEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEEEEEHHHCC
GKPAIVSRGELIEIGGAFRMPEIMRRAGAELDEVGTTNRTHARDYRDAIRPETGVILKVH
CCCCEECCCCEEEECCCCCCHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCEEEEEE
TSNYRIEGFTKEVSPRELAEIAQAGGVPLVNDLGSGTLADLARYGLVHEPTVREAVAEGA
CCCEEEECCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHCCCCCCHHHHHHHCCC
DVVTFSGDKLLGGPQAGFIVGRRDLIARINKNPMKRALRLDKVRLAAVEATLRLYRDPDR
CEEEECCCEECCCCCCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LAARLPTLRYLTRRPEDMAAQAARLKPALAAILGPAFTIDATACRSQIGSGALPLETLEG
HHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHCC
VGLAIASRDGSGGALNRLADGLRRLPVPVIGRIDDNALVLDLRCLEDEAAFLASVTALEG
CCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCHHHHHHHHHHHHCC
AHELA
HHHCC
>Mature Secondary Structure 
SAHPASFPAAPPPVAPPPVAPLRVLPSVDAVLKVELARAATERHGRQATTAAVRTALDE
CCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RRAALRAGAGGAATPEEIAASALARLDAAAAPSLRPVFNLTGTVLHTNLGRAIFAEEAVE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCHHHHHHHHHH
AAVRAMRSAVALEYDLDGGKRGERDDHVRGLVCELTGAEDATLVNNNAAAVLLVLNTLSQ
HHHHHHHHHHEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEEEEEHHHCC
GKPAIVSRGELIEIGGAFRMPEIMRRAGAELDEVGTTNRTHARDYRDAIRPETGVILKVH
CCCCEECCCCEEEECCCCCCHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCEEEEEE
TSNYRIEGFTKEVSPRELAEIAQAGGVPLVNDLGSGTLADLARYGLVHEPTVREAVAEGA
CCCEEEECCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHCCCCCCHHHHHHHCCC
DVVTFSGDKLLGGPQAGFIVGRRDLIARINKNPMKRALRLDKVRLAAVEATLRLYRDPDR
CEEEECCCEECCCCCCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LAARLPTLRYLTRRPEDMAAQAARLKPALAAILGPAFTIDATACRSQIGSGALPLETLEG
HHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHCC
VGLAIASRDGSGGALNRLADGLRRLPVPVIGRIDDNALVLDLRCLEDEAAFLASVTALEG
CCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCHHHHHHHHHHHHCC
AHELA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]