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The map label for this gene is fadE25 [H]

Identifier: 154244575

GI number: 154244575

Start: 697132

End: 698889

Strand: Reverse

Name: fadE25 [H]

Synonym: Xaut_0623

Alternate gene names: 154244575

Gene position: 698889-697132 (Counterclockwise)

Preceding gene: 154244576

Following gene: 154244574

Centisome position: 13.16

GC content: 70.02

Gene sequence:

>1758_bases
ATGGCCACCTATACCGCGCCCGTCGACGACATCGGCTTCCTGCTGACGCGCGTTTTCGACTTCGATGCCACCATGGCCGG
CCTGCCCGGCTTCGAGGAGGTGAATGCCGAACTGGCGGTGAGCGTGCTGGAGGAGGCCGGCAAGTTCGCGGCCGGCGTGC
TGGAGCCCCTCAACCGTCCCGGCGACGAGGAGGGCTGCACCCTCGAGAACGGCCTCGTGACCACGCCCAAGGGCGTTGCT
GATGCGTATCGCGCCTTCGCCGACGCCGGCTGGTGCTCGCTCTCCGGGAATCCCGAATATGGCGGGCAGGGCCTGCCCCG
GGTGCTGCAGATCCTCCTCGACGAGATGCTGTCCTCGGCCAATCTGTCCTTCGGCCTGTTCCCCGGCCTCACCCGCGGCG
CGGTGGAGGCCATCGGCCACCATGCCAGCGCGGAACTGAAGGCCACCTACCTGCCGAAGATGATCTCCGGCGAGTGGACC
GGCGCCATGGCCCTCACCGAGGCCTCCGCCGGCACTGACCTCGGCCTGCTCAATACCCGCGCCGTGCCAAATGGCGACGG
CAGCTATGCCATCACCGGCACCAAGATCTTCATTTCCTCGGGCGACCAGGACTTCGGCGGCAACGTCATCCATCTGGTGC
TCGCGCGCCTGCCCGATGCGCCAAAGGGCGTGAAGGGCATCAGCCTCTTCCTCGCCCCCAAGTTCCTCGTCCATGCGGAC
GGCAGCCTCGGCGCTCGCAACGGCGTGAATGTCGGCGCGCTGGAACACAAGATGGGGATTCACGCCCAGCCCACCTGTGT
CATGAACTATGATGGCGCCACCGGCTGGCTGGTGGGCGAGCCGGGTCGCGGGCTCAACGCCATGTTCACCATGATGAACG
CGGAACGCCTGTTCGTCGGCATCCAGGGCCTCGGCATCGCCGAAGCGGCCAACCAGAAGGCCGTGGCCTACGCCCGTGAG
CGCCTGCAGGGCCACGGCGCCGACGGCACGCCGGGCCCGGTCGCGATCATCAACCATCCCGACGTGCGCAAGATGCTGCT
CACGGGACGCGCTTTCGCCGACGCCGCGCGGGCGCTCGCGGTGTGGACGGCGCTCCAGATGGACATCGCCGACCGCCATC
CCGACGCCACAGTGCGCCGCGAGGCCGATGCGCTGGTGGCGCTCCTGACCCCGGTGGTCAAGGCCGCTTTCACCGATTTC
GGCTTCGAGACGGCGGTGGCGTCCCAGCAGGTGCTGGGCGGGCACGGCTACATCCGCGAATGGGGCATGGAGCAATTTGT
GCGCGACGCGCGCATCGCCCAGATCTACGAGGGCACCAACGGCGTGCAGGCGCTGGACCTCGTGGGCCGCAAGCTCGGGC
TGGAGGGCGGAAAGCTGCCGCAGCGCTTCTTCGACCTCATCAAGGCCGACCTCGACGCCGCCCTGCCCTCCGCCGGCGCC
GCGCTGGTGACGCCGGTGGCCGAGGCCCTGGCCCGGCTTCAGGGCGCGACGGCGCGCCTCGCCGCAAATGGCGGCGCCGT
CGAGGCCGGCGCGGCTGCCACCGATTACCTGCGCCTGTTCGCCCTCGTCGCCCTCGGCTGGATGTGGGTCCGCATGGCTG
CCGCCGCGACGGACGAGGCCGCCACTCCGGTGGCGCAGCGCAAGGCGGTTCTCGCGCGCTTCTTCGTCGAGCGCATGCTG
CCGCAGACGCTCGGCCTCGACGCCGCCCTCGCCCACGGCGCGCCCTCGCTGATGGCGCTCCACGCCGACGCCTTTTGA

Upstream 100 bases:

>100_bases
TGGCGAGCCGGCCACGCTGGAGCGCATCCGCCACATGCTCGCGACCGGCAAGCCCCTGCGCAACTGATCTTCGACGCAAA
CCCATTTCGAGGCAAAACCC

Downstream 100 bases:

>100_bases
CCCACCACACGCCACACGACCAACGGCCAATAGAAAATCAACGACGGAGGGAAGCGATGCTCGGAACGATGATGGATGTC
CCGCTGCTGTTGTCCTCGAT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MATYTAPVDDIGFLLTRVFDFDATMAGLPGFEEVNAELAVSVLEEAGKFAAGVLEPLNRPGDEEGCTLENGLVTTPKGVA
DAYRAFADAGWCSLSGNPEYGGQGLPRVLQILLDEMLSSANLSFGLFPGLTRGAVEAIGHHASAELKATYLPKMISGEWT
GAMALTEASAGTDLGLLNTRAVPNGDGSYAITGTKIFISSGDQDFGGNVIHLVLARLPDAPKGVKGISLFLAPKFLVHAD
GSLGARNGVNVGALEHKMGIHAQPTCVMNYDGATGWLVGEPGRGLNAMFTMMNAERLFVGIQGLGIAEAANQKAVAYARE
RLQGHGADGTPGPVAIINHPDVRKMLLTGRAFADAARALAVWTALQMDIADRHPDATVRREADALVALLTPVVKAAFTDF
GFETAVASQQVLGGHGYIREWGMEQFVRDARIAQIYEGTNGVQALDLVGRKLGLEGGKLPQRFFDLIKADLDAALPSAGA
ALVTPVAEALARLQGATARLAANGGAVEAGAAATDYLRLFALVALGWMWVRMAAAATDEAATPVAQRKAVLARFFVERML
PQTLGLDAALAHGAPSLMALHADAF

Sequences:

>Translated_585_residues
MATYTAPVDDIGFLLTRVFDFDATMAGLPGFEEVNAELAVSVLEEAGKFAAGVLEPLNRPGDEEGCTLENGLVTTPKGVA
DAYRAFADAGWCSLSGNPEYGGQGLPRVLQILLDEMLSSANLSFGLFPGLTRGAVEAIGHHASAELKATYLPKMISGEWT
GAMALTEASAGTDLGLLNTRAVPNGDGSYAITGTKIFISSGDQDFGGNVIHLVLARLPDAPKGVKGISLFLAPKFLVHAD
GSLGARNGVNVGALEHKMGIHAQPTCVMNYDGATGWLVGEPGRGLNAMFTMMNAERLFVGIQGLGIAEAANQKAVAYARE
RLQGHGADGTPGPVAIINHPDVRKMLLTGRAFADAARALAVWTALQMDIADRHPDATVRREADALVALLTPVVKAAFTDF
GFETAVASQQVLGGHGYIREWGMEQFVRDARIAQIYEGTNGVQALDLVGRKLGLEGGKLPQRFFDLIKADLDAALPSAGA
ALVTPVAEALARLQGATARLAANGGAVEAGAAATDYLRLFALVALGWMWVRMAAAATDEAATPVAQRKAVLARFFVERML
PQTLGLDAALAHGAPSLMALHADAF
>Mature_584_residues
ATYTAPVDDIGFLLTRVFDFDATMAGLPGFEEVNAELAVSVLEEAGKFAAGVLEPLNRPGDEEGCTLENGLVTTPKGVAD
AYRAFADAGWCSLSGNPEYGGQGLPRVLQILLDEMLSSANLSFGLFPGLTRGAVEAIGHHASAELKATYLPKMISGEWTG
AMALTEASAGTDLGLLNTRAVPNGDGSYAITGTKIFISSGDQDFGGNVIHLVLARLPDAPKGVKGISLFLAPKFLVHADG
SLGARNGVNVGALEHKMGIHAQPTCVMNYDGATGWLVGEPGRGLNAMFTMMNAERLFVGIQGLGIAEAANQKAVAYARER
LQGHGADGTPGPVAIINHPDVRKMLLTGRAFADAARALAVWTALQMDIADRHPDATVRREADALVALLTPVVKAAFTDFG
FETAVASQQVLGGHGYIREWGMEQFVRDARIAQIYEGTNGVQALDLVGRKLGLEGGKLPQRFFDLIKADLDAALPSAGAA
LVTPVAEALARLQGATARLAANGGAVEAGAAATDYLRLFALVALGWMWVRMAAAATDEAATPVAQRKAVLARFFVERMLP
QTLGLDAALAHGAPSLMALHADAF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=422, Percent_Identity=26.5402843601896, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI21361497, Length=406, Percent_Identity=25.1231527093596, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4557233, Length=360, Percent_Identity=29.1666666666667, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI76496475, Length=423, Percent_Identity=27.4231678486998, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4557235, Length=423, Percent_Identity=27.4231678486998, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4501857, Length=334, Percent_Identity=26.0479041916168, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI7656849, Length=388, Percent_Identity=25.7731958762887, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226958412, Length=382, Percent_Identity=24.869109947644, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI226958414, Length=389, Percent_Identity=24.9357326478149, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI187960098, Length=311, Percent_Identity=27.3311897106109, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4557231, Length=311, Percent_Identity=27.3311897106109, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87082384, Length=339, Percent_Identity=29.2035398230088, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081958, Length=423, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=435, Percent_Identity=28.2758620689655, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=28.0839895013123, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=414, Percent_Identity=25.6038647342995, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=411, Percent_Identity=26.7639902676399, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=360, Percent_Identity=28.3333333333333, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86563383, Length=303, Percent_Identity=29.3729372937294, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI86563381, Length=303, Percent_Identity=29.3729372937294, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=366, Percent_Identity=28.4153005464481, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=28.9855072463768, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=414, Percent_Identity=25.1207729468599, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=27.5109170305677, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=359, Percent_Identity=25.3481894150418, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=288, Percent_Identity=27.0833333333333, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=281, Percent_Identity=27.7580071174377, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646207, Length=387, Percent_Identity=27.6485788113695, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=28.4574468085106, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=26.9129287598945, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=27.1232876712329, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI281363737, Length=391, Percent_Identity=26.8542199488491, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 61239; Mature: 61108

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00445 FGGY_KINASES_2 ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYTAPVDDIGFLLTRVFDFDATMAGLPGFEEVNAELAVSVLEEAGKFAAGVLEPLNRP
CCCCCCCHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GDEEGCTLENGLVTTPKGVADAYRAFADAGWCSLSGNPEYGGQGLPRVLQILLDEMLSSA
CCCCCCEECCCEEECCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHC
NLSFGLFPGLTRGAVEAIGHHASAELKATYLPKMISGEWTGAMALTEASAGTDLGLLNTR
CCCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCHHHCCCCCCCEEEEECCCCCCCCCEECC
AVPNGDGSYAITGTKIFISSGDQDFGGNVIHLVLARLPDAPKGVKGISLFLAPKFLVHAD
CCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECC
GSLGARNGVNVGALEHKMGIHAQPTCVMNYDGATGWLVGEPGRGLNAMFTMMNAERLFVG
CCCCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHCCCEEEEE
IQGLGIAEAANQKAVAYARERLQGHGADGTPGPVAIINHPDVRKMLLTGRAFADAARALA
ECCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHCHHHHHHHHHHH
VWTALQMDIADRHPDATVRREADALVALLTPVVKAAFTDFGFETAVASQQVLGGHGYIRE
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
WGMEQFVRDARIAQIYEGTNGVQALDLVGRKLGLEGGKLPQRFFDLIKADLDAALPSAGA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCH
ALVTPVAEALARLQGATARLAANGGAVEAGAAATDYLRLFALVALGWMWVRMAAAATDEA
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ATPVAQRKAVLARFFVERMLPQTLGLDAALAHGAPSLMALHADAF
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCC
>Mature Secondary Structure 
ATYTAPVDDIGFLLTRVFDFDATMAGLPGFEEVNAELAVSVLEEAGKFAAGVLEPLNRP
CCCCCCHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GDEEGCTLENGLVTTPKGVADAYRAFADAGWCSLSGNPEYGGQGLPRVLQILLDEMLSSA
CCCCCCEECCCEEECCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHC
NLSFGLFPGLTRGAVEAIGHHASAELKATYLPKMISGEWTGAMALTEASAGTDLGLLNTR
CCCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCHHHCCCCCCCEEEEECCCCCCCCCEECC
AVPNGDGSYAITGTKIFISSGDQDFGGNVIHLVLARLPDAPKGVKGISLFLAPKFLVHAD
CCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECC
GSLGARNGVNVGALEHKMGIHAQPTCVMNYDGATGWLVGEPGRGLNAMFTMMNAERLFVG
CCCCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHCCCEEEEE
IQGLGIAEAANQKAVAYARERLQGHGADGTPGPVAIINHPDVRKMLLTGRAFADAARALA
ECCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHCHHHHHHHHHHH
VWTALQMDIADRHPDATVRREADALVALLTPVVKAAFTDFGFETAVASQQVLGGHGYIRE
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
WGMEQFVRDARIAQIYEGTNGVQALDLVGRKLGLEGGKLPQRFFDLIKADLDAALPSAGA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCH
ALVTPVAEALARLQGATARLAANGGAVEAGAAATDYLRLFALVALGWMWVRMAAAATDEA
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ATPVAQRKAVLARFFVERMLPQTLGLDAALAHGAPSLMALHADAF
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]