Click here to switch to the map view.

The map label for this gene is queC

Identifier: 153948926

GI number: 153948926

Start: 3474029

End: 3474727

Strand: Direct

Name: queC

Synonym: YpsIP31758_3085

Alternate gene names: 153948926

Gene position: 3474029-3474727 (Clockwise)

Preceding gene: 153950496

Following gene: 153949760

Centisome position: 73.55

GC content: 47.64

Gene sequence:

>699_bases
ATGAAACGTGCCGTAGTTGTCTTTAGTGGTGGGCAAGATTCCACCACCTGCTTAATTCAAGCGTTACAGCAATATGACGA
AGTACATTGCATTACTTTCGATTACGGCCAACGCCACCGTACGGAAATAGATGTTGCTCGCGAACTTGCACTCCAACTAG
GTGCCACAGCACATAAAGTACTGGATGTCGGTATGTTGAACGAACTGGCCGTCAGTAGCCTGACTCGTGACAGTATTCCT
GTCCCGTCATATGATGCCAACGCTGACGGTGCATTACCCAGTACTTTTGTCCCTGGACGTAACATACTGTTTCTCACCTT
AGCCTCTATTTATGCGTATCAAGTGCAAGCCCAGGCCGTTATCACCGGTGTTTGCGAAACTGACTTTTCTGGCTATCCGG
ATTGCCGCGATGAGTTTATTAAGGCATTGAACCACGCTATCGATTTAGGTATTGGCCGGGATATCGCTTTTATCACCCCC
CTGATGTGGCTTGATAAAGCCGAAACCTGGGCACTAGCCGATTACTATCAACAATTGGATCTCATTCGCCACCATACACT
GACCTGTTATAACGGAATTAAAGGAGACGGCTGTGGCCAATGTGCAGCGTGTCACCTACGGGCTAAAGGCCTGGCATCCT
ATATGGCGAATAAACAGCAGGTTATATTAAACCTAAAGCAAAAGGTGGGGTTAGCCTGA

Upstream 100 bases:

>100_bases
TACCCTTCTGCGTGTTAACTGAGTAACATACTGCCAGTTCTTAATTTATGCTGCAGGGTTAGCCCAATCATTGTTACCTG
CAGCCGTACGAGGTTACCGA

Downstream 100 bases:

>100_bases
TATATAGCGGCCTATCTATATAATATGGCCGCAACACACGCTCTCAATAACCGTTCCCCTTCTCAACCACCGTTTAGGAT
TAATATCAAGCTCCCCGATT

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKRAVVVFSGGQDSTTCLIQALQQYDEVHCITFDYGQRHRTEIDVARELALQLGATAHKVLDVGMLNELAVSSLTRDSIP
VPSYDANADGALPSTFVPGRNILFLTLASIYAYQVQAQAVITGVCETDFSGYPDCRDEFIKALNHAIDLGIGRDIAFITP
LMWLDKAETWALADYYQQLDLIRHHTLTCYNGIKGDGCGQCAACHLRAKGLASYMANKQQVILNLKQKVGLA

Sequences:

>Translated_232_residues
MKRAVVVFSGGQDSTTCLIQALQQYDEVHCITFDYGQRHRTEIDVARELALQLGATAHKVLDVGMLNELAVSSLTRDSIP
VPSYDANADGALPSTFVPGRNILFLTLASIYAYQVQAQAVITGVCETDFSGYPDCRDEFIKALNHAIDLGIGRDIAFITP
LMWLDKAETWALADYYQQLDLIRHHTLTCYNGIKGDGCGQCAACHLRAKGLASYMANKQQVILNLKQKVGLA
>Mature_232_residues
MKRAVVVFSGGQDSTTCLIQALQQYDEVHCITFDYGQRHRTEIDVARELALQLGATAHKVLDVGMLNELAVSSLTRDSIP
VPSYDANADGALPSTFVPGRNILFLTLASIYAYQVQAQAVITGVCETDFSGYPDCRDEFIKALNHAIDLGIGRDIAFITP
LMWLDKAETWALADYYQQLDLIRHHTLTCYNGIKGDGCGQCAACHLRAKGLASYMANKQQVILNLKQKVGLA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=231, Percent_Identity=80.0865800865801, Blast_Score=397, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_YERP3 (A7FLB7)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402045.1
- ProteinModelPortal:   A7FLB7
- SMR:   A7FLB7
- STRING:   A7FLB7
- GeneID:   5385436
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3085
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   PRK11106
- BioCyc:   YPSE349747:YPSIP31758_3085-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR001518
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11587
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25472; Mature: 25472

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAVVVFSGGQDSTTCLIQALQQYDEVHCITFDYGQRHRTEIDVARELALQLGATAHKV
CCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHH
LDVGMLNELAVSSLTRDSIPVPSYDANADGALPSTFVPGRNILFLTLASIYAYQVQAQAV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ITGVCETDFSGYPDCRDEFIKALNHAIDLGIGRDIAFITPLMWLDKAETWALADYYQQLD
HEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
LIRHHTLTCYNGIKGDGCGQCAACHLRAKGLASYMANKQQVILNLKQKVGLA
HHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRAVVVFSGGQDSTTCLIQALQQYDEVHCITFDYGQRHRTEIDVARELALQLGATAHKV
CCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHH
LDVGMLNELAVSSLTRDSIPVPSYDANADGALPSTFVPGRNILFLTLASIYAYQVQAQAV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ITGVCETDFSGYPDCRDEFIKALNHAIDLGIGRDIAFITPLMWLDKAETWALADYYQQLD
HEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
LIRHHTLTCYNGIKGDGCGQCAACHLRAKGLASYMANKQQVILNLKQKVGLA
HHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA