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The map label for this gene is corA [H]

Identifier: 153952115

GI number: 153952115

Start: 1129100

End: 1130083

Strand: Direct

Name: corA [H]

Synonym: JJD26997_1280

Alternate gene names: 153952115

Gene position: 1129100-1130083 (Clockwise)

Preceding gene: 153952328

Following gene: 153951811

Centisome position: 61.19

GC content: 30.49

Gene sequence:

>984_bases
ATGCTCTATGTTTATATCAAAACTCAAAATGCTTTAGTGCAAAGAATCAATTTTAATCTCGATAGTCAAGAGCTACCGCA
AAATATTTTGTGGATTGATTTGCTTCATCCAAGCACAGCGGAAATTGCTTTTATATCAAGCAAATTTAATCTTGAATTTC
CTACAAAAGAAGAAAGAGAGGAAATAGAACTTAGTGCAAAATATTGGGAAGATAACGCAACAATAACTATCAATGCTCAT
TTTTTAATAAAAGAGCTTCAAAATAGCCAAGAAGATGAAAATTTAATCAAACTTCGCACAGAAATTGTTACTTTTGTTAC
AGCTAAAAATATCTTATTTACAATAAGATATAACGAATTTAGTACTTTTGAAGAAATTCAAGCAAGGATTTTAGCTAGTC
CGAAGAATTTTGAAGATGGTTTTGATATTATTGATAAAATGTTTGAAGTGCGCGTTGAAAAAGATGCGGATTTACTAGAA
TGGATAGATAAAGAAGCAAGACGTTTAAGAACAAGTGTTTTAGAAAAAAAAGATGAATATAGTTATGATGAAATGCTAAA
GGATATTTCAAGTTTGCAAGAGCTTAATATGCGTGTAAGGGATTCTTTATTTGATAAGCGTCGCGCTATGACTTCTTTGT
TAAAAAGCGATAAAATTGATAAAGATATAAAGCAAAATCTCACTATAGTTTTAAAAGACTTAAATTCTTTGGTTGAATTT
AGCGTTTCACAACTTAGTATCTTAGATAACATCCAAACCATTTTAGCCAGCCAAATCAATATAGAACAAAATAAAATCAT
TAAAATTTTCACCGTTGCAACTGTTGCCATGATGCCGCCTACTTTAGTAGGAACGGTTTATGGTATGAACTTTAAATTCA
TGCCCGAGCTTGAGTTTCATTATGCCTATCCTATAGTGCTTGGCGTAATGGTGATTTCTATGATTTTACCTTTAATCGTT
TTTAAGAAAAAAGGATGGTTATAA

Upstream 100 bases:

>100_bases
AGCTTTAGGTGGAAAATTTGGTTTTGGATTTATAAAAATTAAAAAATTGATTTTTAAACGAATCAAGGTATAATTTCAAA
GTTAAAAATAAGGAATAACT

Downstream 100 bases:

>100_bases
AAATTTATTAAGGAGAAACAATGGATACAATAAACATAGGAATTTTGACCCTAAGCGATAGAGCAAGCAGTGGCATATAC
GAAGATAAAGCCACTGCTGA

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MLYVYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSTAEIAFISSKFNLEFPTKEEREEIELSAKYWEDNATITINAH
FLIKELQNSQEDENLIKLRTEIVTFVTAKNILFTIRYNEFSTFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLE
WIDKEARRLRTSVLEKKDEYSYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
SVSQLSILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLVGTVYGMNFKFMPELEFHYAYPIVLGVMVISMILPLIV
FKKKGWL

Sequences:

>Translated_327_residues
MLYVYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSTAEIAFISSKFNLEFPTKEEREEIELSAKYWEDNATITINAH
FLIKELQNSQEDENLIKLRTEIVTFVTAKNILFTIRYNEFSTFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLE
WIDKEARRLRTSVLEKKDEYSYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
SVSQLSILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLVGTVYGMNFKFMPELEFHYAYPIVLGVMVISMILPLIV
FKKKGWL
>Mature_327_residues
MLYVYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSTAEIAFISSKFNLEFPTKEEREEIELSAKYWEDNATITINAH
FLIKELQNSQEDENLIKLRTEIVTFVTAKNILFTIRYNEFSTFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLE
WIDKEARRLRTSVLEKKDEYSYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
SVSQLSILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLVGTVYGMNFKFMPELEFHYAYPIVLGVMVISMILPLIV
FKKKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=302, Percent_Identity=31.1258278145695, Blast_Score=167, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 38215; Mature: 38215

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYVYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSTAEIAFISSKFNLEFPTKEERE
CEEEEEECCHHHHHHHCCCCCHHHCCCCEEEEEEECCCCCEEEEEECEEEECCCCCHHHH
EIELSAKYWEDNATITINAHFLIKELQNSQEDENLIKLRTEIVTFVTAKNILFTIRYNEF
HHHHHHEEECCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCEEEEEEECCC
STFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLEWIDKEARRLRTSVLEKKDEY
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
SYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SVSQLSILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLVGTVYGMNFKFMPELEFH
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCHHHHHHCCCCEEECCCCCHH
YAYPIVLGVMVISMILPLIVFKKKGWL
HHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLYVYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSTAEIAFISSKFNLEFPTKEERE
CEEEEEECCHHHHHHHCCCCCHHHCCCCEEEEEEECCCCCEEEEEECEEEECCCCCHHHH
EIELSAKYWEDNATITINAHFLIKELQNSQEDENLIKLRTEIVTFVTAKNILFTIRYNEF
HHHHHHEEECCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCEEEEEEECCC
STFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLEWIDKEARRLRTSVLEKKDEY
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
SYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SVSQLSILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLVGTVYGMNFKFMPELEFH
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCHHHHHHCCCCEEECCCCCHH
YAYPIVLGVMVISMILPLIVFKKKGWL
HHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]