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The map label for this gene is era [H]

Identifier: 153951129

GI number: 153951129

Start: 1182098

End: 1182973

Strand: Direct

Name: era [H]

Synonym: JJD26997_1338

Alternate gene names: 153951129

Gene position: 1182098-1182973 (Clockwise)

Preceding gene: 153951339

Following gene: 153952273

Centisome position: 64.07

GC content: 32.53

Gene sequence:

>876_bases
GTGAAAAGTGGCTTTGTTAGCATCATAGGGCGTACTAATGCAGGAAAAAGTACTTTAATCAATTCCTTGTTAGAAGAGAA
AATCGCCCTAGTTTCTCACAAACAAAACGCCACAAGGCGCAAAATCAAGGCCATAGTGATTCATGAAAAAAATCAAATCA
TTTTTATCGATACCCCAGGACTTCACGAAAGCGGTGCTACATTTAATCAACTGCTTGTCCAAAGTGCTATTAAATCCATG
GAGGATTGTGATGTGATTTTATTTGTGGCGAGTGTTTTTGATAGTACAAAAGACTATGAAAATTTTCTTAGCCTCAATCC
ACAAGTATCACACATCATCGCTTTAAATAAAGTAGATTTAACCGACAATGCTACGCTTTTAAAAAAACTTAGCGAATATG
CAAAATTTAGCGAACATTTTAAGGCTATACTGCCTTATTCCTCTAAGAAAAAAAGCTATAAAAAAGGCTTGTTAGATGAA
ATAGTAAAATGCCTTAACGAACATGAATATTTTTATGATCCTGAATTTTTAAGTGTAAATAGCGAAAAAGAACTTTATAG
GGATTTCATACTTGAAAGCATTTATGAAAATTTAAGCGATGAGCTTCCTTATAGTAGTGAAGTGCTTATCAATCGCACTA
AAGACACACCTAATCTTTTAATCCTAGAAGCCAATATCATCACAGATACAAACTCTCACAAAGGTATGTTTATAGGAAAA
GAGGGGGCAACTTTAAAAAGAATAGGCAAAGATGCACGCTTTAAAATTTCAAAACTTGCCCAAAAAAAGGTACTTTTAAA
GCTTTTTGTAACAGTGAAAAAAAACTGGCAAAAAGATGAAGAATTTTTAAAAAAACTTCTAAATGATGAAAATTAA

Upstream 100 bases:

>100_bases
CTGATGAGTATGCGGGTAAAAAATTCGTAGTGGATAAAAAAATGGTAGAAGAAAAACTCGGAGATATCATAGAAAATAAA
GATCTTGCAAGGTATATTTT

Downstream 100 bases:

>100_bases
TTCATTAAATAAAATAAATTTTATAAAATCCACAGATTTACTTTATGCCCAAAGAACGGGAATATTCAAAGAAGACGAAC
TTTTTAACAATTTAACCGCA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVIHEKNQIIFIDTPGLHESGATFNQLLVQSAIKSM
EDCDVILFVASVFDSTKDYENFLSLNPQVSHIIALNKVDLTDNATLLKKLSEYAKFSEHFKAILPYSSKKKSYKKGLLDE
IVKCLNEHEYFYDPEFLSVNSEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMFIGK
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN

Sequences:

>Translated_291_residues
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVIHEKNQIIFIDTPGLHESGATFNQLLVQSAIKSM
EDCDVILFVASVFDSTKDYENFLSLNPQVSHIIALNKVDLTDNATLLKKLSEYAKFSEHFKAILPYSSKKKSYKKGLLDE
IVKCLNEHEYFYDPEFLSVNSEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMFIGK
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN
>Mature_291_residues
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVIHEKNQIIFIDTPGLHESGATFNQLLVQSAIKSM
EDCDVILFVASVFDSTKDYENFLSLNPQVSHIIALNKVDLTDNATLLKKLSEYAKFSEHFKAILPYSSKKKSYKKGLLDE
IVKCLNEHEYFYDPEFLSVNSEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMFIGK
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=302, Percent_Identity=24.5033112582781, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788919, Length=288, Percent_Identity=32.6388888888889, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33226; Mature: 33226

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVIHEKNQIIFIDTPG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEECCCCEEEEECCC
LHESGATFNQLLVQSAIKSMEDCDVILFVASVFDSTKDYENFLSLNPQVSHIIALNKVDL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEEEECC
TDNATLLKKLSEYAKFSEHFKAILPYSSKKKSYKKGLLDEIVKCLNEHEYFYDPEFLSVN
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCEEECC
SEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMFIGK
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCEEEEC
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVIHEKNQIIFIDTPG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEECCCCEEEEECCC
LHESGATFNQLLVQSAIKSMEDCDVILFVASVFDSTKDYENFLSLNPQVSHIIALNKVDL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEEEECC
TDNATLLKKLSEYAKFSEHFKAILPYSSKKKSYKKGLLDEIVKCLNEHEYFYDPEFLSVN
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCEEECC
SEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMFIGK
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCEEEEC
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA