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The map label for this gene is rbsK [H]

Identifier: 153936999

GI number: 153936999

Start: 1666245

End: 1667156

Strand: Direct

Name: rbsK [H]

Synonym: CLC_1595

Alternate gene names: 153936999

Gene position: 1666245-1667156 (Clockwise)

Preceding gene: 153937183

Following gene: 153935651

Centisome position: 44.31

GC content: 29.82

Gene sequence:

>912_bases
ATGGATATTGCAGTTATTGGTTCAAATATGGTAGATTTGATAAGTTATATTGATAGAATGCCTAAAGAAGGTGAGACTTT
AGAAGCACTAGATTTTAAAATGGGATTTGGGGGTAAGGGAGCAAACCAGGCCGTTACAGCTGCAAGATTAAAATCAGATG
TTATGATGGTAAGTAAAGTTGGAGATGATTTATTTGGACAAAACACTATTAAAAATTTAAAAAACAATGGTGTAAATACA
GATTTTGTAACTGTTCAAAAAAATCAAGCTAGTGGAGTTGCACCTATTTTTGTTGATAGAGAATCTAAAAATAGCATTTT
AATTATTAAAGGTGCCAATAAAAATTTATCTCCTACAGATATAGATGATGCAAGTGAAGAATTGAAAAAGTGTTCTTTAA
TTATTTTACAATTGGAAATTGAATTAGAAACTGTTTATTATGCTATAGATTTTGCAAATAAAAATAATATTCCTGTATTG
TTAAATCCTGCTCCTGCTACAAAAGAGCTTGATTTCGATTATGTTTATAAATGTGATTTCTTTGTGCCAAATGAAACAGA
ATTAGAGATTTTAACAAATAAACCTGTAAATACAATAGGAAAGATAAAAGAAGCTGCTCATTTAATTGGGGATAAAGGTG
TTAAAAATGTAATTGTTACAATGGGTAGTAGAGGTTTACTATGGATTAATAAAGATGAAGAACATTTTATAAAAGCACGT
AAAGTTGATGCTGTGGATACCACTGGTGCTGGCGATGGATTTATTGGATGTTTTGCACATTATTATGTAGCCACAAAAAA
CATATTATTAGCTCTTGAAAAAGCAACAGCTTATGCAGCTCTTAGTGTTACAAGATATGGTACTCAAACTTCTTATCCTA
CAAAGGAGGAGTTTGAAAAATTTTTAAAATAA

Upstream 100 bases:

>100_bases
TTTAAATAAAACTCCAAGCTTTCAATATAAAGTAAGTAAATACTAAAATAAGTAGATGTAAGATGTACTACATTAAATAT
TGAAAGGAAGTGCTTAAATA

Downstream 100 bases:

>100_bases
GTTTTAGGTTTGAGAAATTTTACTGTATAAAAATATATTTTTAAAAACAAAGACTCCTATACATTAGTGTAGGGTTTTTT
TGTTTTGTGGAAAATAAAAA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDIAVIGSNMVDLISYIDRMPKEGETLEALDFKMGFGGKGANQAVTAARLKSDVMMVSKVGDDLFGQNTIKNLKNNGVNT
DFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTDIDDASEELKKCSLIILQLEIELETVYYAIDFANKNNIPVL
LNPAPATKELDFDYVYKCDFFVPNETELEILTNKPVNTIGKIKEAAHLIGDKGVKNVIVTMGSRGLLWINKDEEHFIKAR
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEKFLK

Sequences:

>Translated_303_residues
MDIAVIGSNMVDLISYIDRMPKEGETLEALDFKMGFGGKGANQAVTAARLKSDVMMVSKVGDDLFGQNTIKNLKNNGVNT
DFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTDIDDASEELKKCSLIILQLEIELETVYYAIDFANKNNIPVL
LNPAPATKELDFDYVYKCDFFVPNETELEILTNKPVNTIGKIKEAAHLIGDKGVKNVIVTMGSRGLLWINKDEEHFIKAR
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEKFLK
>Mature_303_residues
MDIAVIGSNMVDLISYIDRMPKEGETLEALDFKMGFGGKGANQAVTAARLKSDVMMVSKVGDDLFGQNTIKNLKNNGVNT
DFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTDIDDASEELKKCSLIILQLEIELETVYYAIDFANKNNIPVL
LNPAPATKELDFDYVYKCDFFVPNETELEILTNKPVNTIGKIKEAAHLIGDKGVKNVIVTMGSRGLLWINKDEEHFIKAR
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEKFLK

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=41.554054054054, Blast_Score=220, Evalue=1e-57,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=37.6666666666667, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI87082343, Length=308, Percent_Identity=29.2207792207792, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788484, Length=250, Percent_Identity=22.8, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788493, Length=74, Percent_Identity=37.8378378378378, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789432, Length=268, Percent_Identity=26.4925373134328, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788491, Length=269, Percent_Identity=22.3048327137546, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=307, Percent_Identity=39.413680781759, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6319884, Length=334, Percent_Identity=30.5389221556886, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=35.3135313531353, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24583886, Length=305, Percent_Identity=29.5081967213115, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33367; Mature: 33367

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAVIGSNMVDLISYIDRMPKEGETLEALDFKMGFGGKGANQAVTAARLKSDVMMVSKV
CEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
GDDLFGQNTIKNLKNNGVNTDFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTD
CCHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCC
IDDASEELKKCSLIILQLEIELETVYYAIDFANKNNIPVLLNPAPATKELDFDYVYKCDF
CCHHHHHHHHEEEEEEEEEEEEEEEEEEEEECCCCCCCEEECCCCCCCCCCCCEEEEEEE
FVPNETELEILTNKPVNTIGKIKEAAHLIGDKGVKNVIVTMGSRGLLWINKDEEHFIKAR
ECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHH
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEK
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECHHEEEEEEEEECCCCCCCCCHHHHHH
FLK
HCC
>Mature Secondary Structure
MDIAVIGSNMVDLISYIDRMPKEGETLEALDFKMGFGGKGANQAVTAARLKSDVMMVSKV
CEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
GDDLFGQNTIKNLKNNGVNTDFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTD
CCHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCC
IDDASEELKKCSLIILQLEIELETVYYAIDFANKNNIPVLLNPAPATKELDFDYVYKCDF
CCHHHHHHHHEEEEEEEEEEEEEEEEEEEEECCCCCCCEEECCCCCCCCCCCCEEEEEEE
FVPNETELEILTNKPVNTIGKIKEAAHLIGDKGVKNVIVTMGSRGLLWINKDEEHFIKAR
ECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHH
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEK
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECHHEEEEEEEEECCCCCCCCCHHHHHH
FLK
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]