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The map label for this gene is mcp4 [H]

Identifier: 153935589

GI number: 153935589

Start: 1774188

End: 1775660

Strand: Direct

Name: mcp4 [H]

Synonym: CLC_1686

Alternate gene names: 153935589

Gene position: 1774188-1775660 (Clockwise)

Preceding gene: 153934941

Following gene: 153935576

Centisome position: 47.18

GC content: 29.87

Gene sequence:

>1473_bases
TTGAGAATATTTAAAGATAATGCCATTGAAAAGGAAATAATAAAAATATCACAGGATTTTCAAAATCAAAATGTACATGC
TCTAGATGAAATAGAAGGGTCTGCAAGTAAAAATAGAATGGTAAGATTTACTGCAGGTATAGCTAAAATAGTACAAGTTA
TATCTCCTAAGGTAAAAAAATTGATAAATGGAGTATTATCAATTACTACTAGAATAAGTACTTTTTCCGTAAACTTAGAT
TATTCTGGAGAGCATCTTAAAAAATCAGCAGATAAGTTATATAATTCTTCCGGAGTTCTAAACTCATCTATTAAAGAAGT
AAAAGAGGCTATGCAGCAGATAACTTTAGCTATTGAAGAGGATGTAGAAACCGTTGAGCACATAAGTAGTGGTAATATAG
AACTAATAAAATATATGGATGAAAATAAAAAGAATTTAGGTCTTGTGAAAAATGTAAATAAAGAATTGGAATTTAAGGCT
CAATCTATGGAGAAAGATATGACAGAATTAAATTCTATACTAGAAAACATGAAAACTATAGTTACTGGTATGAGTGAAAT
AGCATCAAAAACTAATCTATTAGCCTTAAATGCTAGCATAGAAGCTGCAAGAGCAGGAGAGGCAGGGAAGGGCTTTGCTG
TTGTAGCGGAGGAAGTTAGAAAACTTTCTGAAAGCACATCAAAACAACTAGAGAAGATGGAGGAATTTGTCAACAATATA
GGGACTTGCTCTACTAATAGTAGTAAAAGTGTAAAGGATACTATAGGAAGTATAGGTGAACTAGGGGAATATACACAAGC
TATATCTTCGTCCTCTTCTAAAGTTAGAGAAGCTATAGATATTGAAGTAAAGAGTATAGAACTTCTGGCTGCTAGTATGC
AAGAAATAAATGCTTCAAGTGAAGAAATAAATAGTAATATGGATATCATAGGTGAAAATGTACAGGAAGTAAGTAAAGAA
GCTGCTGTTTTAAGTGAAAAATCTTTAGAAATAAAATATCTAGCAGATGAAATGGATAAAATAGATGATGAAGTATCTAA
TTTGGCTAAACTAAGTGGTGATATAACTGGGGAAAATTACTTTAAAATTACAAATAAAGATTTTATTGTGGCTATAGACA
ATGCTATAAAAGCACATGAAAATTGGGTACAACAACTCCAAAATATGGCTATGGAAAATAAAATAAAACCAATACAAACA
GATGGACAAAAATGTGGATTTGGTCATTTTTATAATTCTGTAATGCCAAGAAATGAGAAGATAAAAGAAATTTGGATTAA
AATAGATGATATACATAAAGAATTACATAAAGTAGGGGGAATTGTAAAAAGTAATATAAAGGATGGACATACAGAGAAAG
CTAAAGAAAATAGTAAAAAAGCTACACAGTTGTCACAAACAATTATAAGTATGTTGTCTCATATAAAATCAATTGCTATA
GAAACTGATAAGGAAGGTAATTTGGTTCTTTAA

Upstream 100 bases:

>100_bases
GGCTTAATTAAAATTGATATTTAATTGCAGTTGAAAGCAAATAATTATTCTTGTATAATTAAAAAGTGATTAATAAATAT
GTAAAATAGGGGTGAAATCA

Downstream 100 bases:

>100_bases
TAATTGAATTTTATAAATATATAGGAAATATAATTGATTATATTAATAGTTTTTAATATAATATTTAATGCATTATAAAA
ATATAATGTGGGTGGGAGAG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MRIFKDNAIEKEIIKISQDFQNQNVHALDEIEGSASKNRMVRFTAGIAKIVQVISPKVKKLINGVLSITTRISTFSVNLD
YSGEHLKKSADKLYNSSGVLNSSIKEVKEAMQQITLAIEEDVETVEHISSGNIELIKYMDENKKNLGLVKNVNKELEFKA
QSMEKDMTELNSILENMKTIVTGMSEIASKTNLLALNASIEAARAGEAGKGFAVVAEEVRKLSESTSKQLEKMEEFVNNI
GTCSTNSSKSVKDTIGSIGELGEYTQAISSSSSKVREAIDIEVKSIELLAASMQEINASSEEINSNMDIIGENVQEVSKE
AAVLSEKSLEIKYLADEMDKIDDEVSNLAKLSGDITGENYFKITNKDFIVAIDNAIKAHENWVQQLQNMAMENKIKPIQT
DGQKCGFGHFYNSVMPRNEKIKEIWIKIDDIHKELHKVGGIVKSNIKDGHTEKAKENSKKATQLSQTIISMLSHIKSIAI
ETDKEGNLVL

Sequences:

>Translated_490_residues
MRIFKDNAIEKEIIKISQDFQNQNVHALDEIEGSASKNRMVRFTAGIAKIVQVISPKVKKLINGVLSITTRISTFSVNLD
YSGEHLKKSADKLYNSSGVLNSSIKEVKEAMQQITLAIEEDVETVEHISSGNIELIKYMDENKKNLGLVKNVNKELEFKA
QSMEKDMTELNSILENMKTIVTGMSEIASKTNLLALNASIEAARAGEAGKGFAVVAEEVRKLSESTSKQLEKMEEFVNNI
GTCSTNSSKSVKDTIGSIGELGEYTQAISSSSSKVREAIDIEVKSIELLAASMQEINASSEEINSNMDIIGENVQEVSKE
AAVLSEKSLEIKYLADEMDKIDDEVSNLAKLSGDITGENYFKITNKDFIVAIDNAIKAHENWVQQLQNMAMENKIKPIQT
DGQKCGFGHFYNSVMPRNEKIKEIWIKIDDIHKELHKVGGIVKSNIKDGHTEKAKENSKKATQLSQTIISMLSHIKSIAI
ETDKEGNLVL
>Mature_490_residues
MRIFKDNAIEKEIIKISQDFQNQNVHALDEIEGSASKNRMVRFTAGIAKIVQVISPKVKKLINGVLSITTRISTFSVNLD
YSGEHLKKSADKLYNSSGVLNSSIKEVKEAMQQITLAIEEDVETVEHISSGNIELIKYMDENKKNLGLVKNVNKELEFKA
QSMEKDMTELNSILENMKTIVTGMSEIASKTNLLALNASIEAARAGEAGKGFAVVAEEVRKLSESTSKQLEKMEEFVNNI
GTCSTNSSKSVKDTIGSIGELGEYTQAISSSSSKVREAIDIEVKSIELLAASMQEINASSEEINSNMDIIGENVQEVSKE
AAVLSEKSLEIKYLADEMDKIDDEVSNLAKLSGDITGENYFKITNKDFIVAIDNAIKAHENWVQQLQNMAMENKIKPIQT
DGQKCGFGHFYNSVMPRNEKIKEIWIKIDDIHKELHKVGGIVKSNIKDGHTEKAKENSKKATQLSQTIISMLSHIKSIAI
ETDKEGNLVL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=253, Percent_Identity=26.8774703557312, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI2367378, Length=220, Percent_Identity=28.1818181818182, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787690, Length=138, Percent_Identity=31.1594202898551, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789453, Length=74, Percent_Identity=43.2432432432432, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788195, Length=207, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54268; Mature: 54268

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFKDNAIEKEIIKISQDFQNQNVHALDEIEGSASKNRMVRFTAGIAKIVQVISPKVKK
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEHHHHHHHHHHHHCHHHHH
LINGVLSITTRISTFSVNLDYSGEHLKKSADKLYNSSGVLNSSIKEVKEAMQQITLAIEE
HHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
DVETVEHISSGNIELIKYMDENKKNLGLVKNVNKELEFKAQSMEKDMTELNSILENMKTI
HHHHHHHHCCCCEEEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGMSEIASKTNLLALNASIEAARAGEAGKGFAVVAEEVRKLSESTSKQLEKMEEFVNNI
HHHHHHHHCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTCSTNSSKSVKDTIGSIGELGEYTQAISSSSSKVREAIDIEVKSIELLAASMQEINASS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EEINSNMDIIGENVQEVSKEAAVLSEKSLEIKYLADEMDKIDDEVSNLAKLSGDITGENY
HHHCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
FKITNKDFIVAIDNAIKAHENWVQQLQNMAMENKIKPIQTDGQKCGFGHFYNSVMPRNEK
EEEECCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHH
IKEIWIKIDDIHKELHKVGGIVKSNIKDGHTEKAKENSKKATQLSQTIISMLSHIKSIAI
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ETDKEGNLVL
ECCCCCCCCC
>Mature Secondary Structure
MRIFKDNAIEKEIIKISQDFQNQNVHALDEIEGSASKNRMVRFTAGIAKIVQVISPKVKK
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEHHHHHHHHHHHHCHHHHH
LINGVLSITTRISTFSVNLDYSGEHLKKSADKLYNSSGVLNSSIKEVKEAMQQITLAIEE
HHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
DVETVEHISSGNIELIKYMDENKKNLGLVKNVNKELEFKAQSMEKDMTELNSILENMKTI
HHHHHHHHCCCCEEEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGMSEIASKTNLLALNASIEAARAGEAGKGFAVVAEEVRKLSESTSKQLEKMEEFVNNI
HHHHHHHHCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTCSTNSSKSVKDTIGSIGELGEYTQAISSSSSKVREAIDIEVKSIELLAASMQEINASS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EEINSNMDIIGENVQEVSKEAAVLSEKSLEIKYLADEMDKIDDEVSNLAKLSGDITGENY
HHHCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
FKITNKDFIVAIDNAIKAHENWVQQLQNMAMENKIKPIQTDGQKCGFGHFYNSVMPRNEK
EEEECCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHH
IKEIWIKIDDIHKELHKVGGIVKSNIKDGHTEKAKENSKKATQLSQTIISMLSHIKSIAI
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ETDKEGNLVL
ECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]