Click here to switch to the map view.

The map label for this gene is alr [H]

Identifier: 153934941

GI number: 153934941

Start: 1772598

End: 1773767

Strand: Direct

Name: alr [H]

Synonym: CLC_1685

Alternate gene names: 153934941

Gene position: 1772598-1773767 (Clockwise)

Preceding gene: 153935348

Following gene: 153935589

Centisome position: 47.14

GC content: 29.66

Gene sequence:

>1170_bases
ATGTTTAGAAATCATAGACCGGTTTGGGAAGAAGTAAACTTAGACAATCTATCTTATAATATGAGAAACATTAAAAAGAA
AGTTAACTGTAAAGAAATTTTTGCAGTTGTAAAAGCTAATGGTTATGGACATGGTGCACTAGATATAGCTTCAACTTTAC
TTGAAAATGGTGCCACTAGACTTTCTGTTGCTTGTCTTAGCGAAGCTACTGAACTTAGGGAAGGTGGTATAACCTGTCCT
ATTAATATTTTAGGAATTACTCCTCCAACCTTATTTGAAGATATAATAGACTATAATATTGAACCTGTAGTTTTTTCTTA
TGATTGTGCAAATCAATTATCAAAAGCAGCTTCCTTAAAAAATAGGATAGTAAAGACACATATTGCAGTTGATACTGGAA
TGGGAAGATTAGGATTTGATCCTACAGTGGAAAGCTTAGAAGAGATAAAAAGAATACAGGATCTATCTAATATTAAAATT
GAAGGATTATGTTCTCATTTTAGTAGTTCAGACGAAAAGGACAAAAGTTATTCAGAATATCAATTTAAAATATTTCAAAA
CTTTAGAAAAAAATTGATAGAAATGAATATGAAAATTCCAATTTATCATATGTCAAATAGTGCAGCAATTATAGATCTTC
CTAGTACCTACTTAGATGGGGTAAGAGCTGGAATAATATTATATGGATATTATCCTTCTATGGAGGTAAATAAAGAGAAT
CTGCACATTAAGCAAGTGATGACTTTAAAAGCAAATATTGTGCATATAAAAACAATAGATTCGGGAAAATATGTTGGTTA
TAATAGGAAGTTTAAAACCAAAAGGAAAAGCAAAATTGCTATTCTTCCTTTAGGGTATGGAGATGGATATACTAGATTTT
TGTCAAATAGGGGTAAAGTTATAATAAATGGACAATATGCTCCTATTGTTGGAAACATATGCATGGATCAATGTATGATA
GATGTTACAGATATTAAAGAGGTTAAAGTAGGAGATGAAGTAATAATTATTGGTAAGGACAATATTAATAATTTAAGATA
TGATGCAGAGGATATAGCGTCTAAGGTAGGTATGACTAGTGGAGAAATTATGTCTATAATAAGTAAGAGAGTGCCAAGGG
TTTATATTAAAAATGGAAATATTGTAAAAGTTAGAAATTATATAGCTTAA

Upstream 100 bases:

>100_bases
TTATAAAATAGAATATGGTCAATCCTTTCACAAAATTGGTTTTTACTCTTAAATTATCAAAAATAATTAAAAGAATACGA
AAGAAAGAGGAATGATATTT

Downstream 100 bases:

>100_bases
AGGATAAAATAAAAATTTAGAAGATGTCTAAAAATAAAATATATTTAATTTTAGTACTGTAAAGATAAAAAATATACTTA
TAAACTAAATCATTTTACTA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MFRNHRPVWEEVNLDNLSYNMRNIKKKVNCKEIFAVVKANGYGHGALDIASTLLENGATRLSVACLSEATELREGGITCP
INILGITPPTLFEDIIDYNIEPVVFSYDCANQLSKAASLKNRIVKTHIAVDTGMGRLGFDPTVESLEEIKRIQDLSNIKI
EGLCSHFSSSDEKDKSYSEYQFKIFQNFRKKLIEMNMKIPIYHMSNSAAIIDLPSTYLDGVRAGIILYGYYPSMEVNKEN
LHIKQVMTLKANIVHIKTIDSGKYVGYNRKFKTKRKSKIAILPLGYGDGYTRFLSNRGKVIINGQYAPIVGNICMDQCMI
DVTDIKEVKVGDEVIIIGKDNINNLRYDAEDIASKVGMTSGEIMSIISKRVPRVYIKNGNIVKVRNYIA

Sequences:

>Translated_389_residues
MFRNHRPVWEEVNLDNLSYNMRNIKKKVNCKEIFAVVKANGYGHGALDIASTLLENGATRLSVACLSEATELREGGITCP
INILGITPPTLFEDIIDYNIEPVVFSYDCANQLSKAASLKNRIVKTHIAVDTGMGRLGFDPTVESLEEIKRIQDLSNIKI
EGLCSHFSSSDEKDKSYSEYQFKIFQNFRKKLIEMNMKIPIYHMSNSAAIIDLPSTYLDGVRAGIILYGYYPSMEVNKEN
LHIKQVMTLKANIVHIKTIDSGKYVGYNRKFKTKRKSKIAILPLGYGDGYTRFLSNRGKVIINGQYAPIVGNICMDQCMI
DVTDIKEVKVGDEVIIIGKDNINNLRYDAEDIASKVGMTSGEIMSIISKRVPRVYIKNGNIVKVRNYIA
>Mature_389_residues
MFRNHRPVWEEVNLDNLSYNMRNIKKKVNCKEIFAVVKANGYGHGALDIASTLLENGATRLSVACLSEATELREGGITCP
INILGITPPTLFEDIIDYNIEPVVFSYDCANQLSKAASLKNRIVKTHIAVDTGMGRLGFDPTVESLEEIKRIQDLSNIKI
EGLCSHFSSSDEKDKSYSEYQFKIFQNFRKKLIEMNMKIPIYHMSNSAAIIDLPSTYLDGVRAGIILYGYYPSMEVNKEN
LHIKQVMTLKANIVHIKTIDSGKYVGYNRKFKTKRKSKIAILPLGYGDGYTRFLSNRGKVIINGQYAPIVGNICMDQCMI
DVTDIKEVKVGDEVIIIGKDNINNLRYDAEDIASKVGMTSGEIMSIISKRVPRVYIKNGNIVKVRNYIA

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=375, Percent_Identity=29.6, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787439, Length=377, Percent_Identity=29.973474801061, Blast_Score=155, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43759; Mature: 43759

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00395 ALANINE_RACEMASE ; PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRNHRPVWEEVNLDNLSYNMRNIKKKVNCKEIFAVVKANGYGHGALDIASTLLENGATR
CCCCCCCCHHHCCCCCCCCHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHHHCCCCE
LSVACLSEATELREGGITCPINILGITPPTLFEDIIDYNIEPVVFSYDCANQLSKAASLK
EEHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHH
NRIVKTHIAVDTGMGRLGFDPTVESLEEIKRIQDLSNIKIEGLCSHFSSSDEKDKSYSEY
HHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHH
QFKIFQNFRKKLIEMNMKIPIYHMSNSAAIIDLPSTYLDGVRAGIILYGYYPSMEVNKEN
HHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCHHHHCHHHEEEEEEEECCCCEECCCC
LHIKQVMTLKANIVHIKTIDSGKYVGYNRKFKTKRKSKIAILPLGYGDGYTRFLSNRGKV
EEEEEEEEEEEEEEEEEEECCCCEECCCCCCCCCCCCEEEEEEECCCCCHHHHHCCCCEE
IINGQYAPIVGNICMDQCMIDVTDIKEVKVGDEVIIIGKDNINNLRYDAEDIASKVGMTS
EECCCCCCHHHHHHHHHHEEECCCCEEEECCCEEEEEECCCCCCCEECHHHHHHHHCCCC
GEIMSIISKRVPRVYIKNGNIVKVRNYIA
HHHHHHHHHCCCEEEEECCCEEEEECCCC
>Mature Secondary Structure
MFRNHRPVWEEVNLDNLSYNMRNIKKKVNCKEIFAVVKANGYGHGALDIASTLLENGATR
CCCCCCCCHHHCCCCCCCCHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHHHCCCCE
LSVACLSEATELREGGITCPINILGITPPTLFEDIIDYNIEPVVFSYDCANQLSKAASLK
EEHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHH
NRIVKTHIAVDTGMGRLGFDPTVESLEEIKRIQDLSNIKIEGLCSHFSSSDEKDKSYSEY
HHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHH
QFKIFQNFRKKLIEMNMKIPIYHMSNSAAIIDLPSTYLDGVRAGIILYGYYPSMEVNKEN
HHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCHHHHCHHHEEEEEEEECCCCEECCCC
LHIKQVMTLKANIVHIKTIDSGKYVGYNRKFKTKRKSKIAILPLGYGDGYTRFLSNRGKV
EEEEEEEEEEEEEEEEEEECCCCEECCCCCCCCCCCCEEEEEEECCCCCHHHHHCCCCEE
IINGQYAPIVGNICMDQCMIDVTDIKEVKVGDEVIIIGKDNINNLRYDAEDIASKVGMTS
EECCCCCCHHHHHHHHHHEEECCCCEEEECCCEEEEEECCCCCCCEECHHHHHHHHCCCC
GEIMSIISKRVPRVYIKNGNIVKVRNYIA
HHHHHHHHHCCCEEEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA