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The map label for this gene is hexR [C]

Identifier: 153935531

GI number: 153935531

Start: 1861553

End: 1862437

Strand: Reverse

Name: hexR [C]

Synonym: CLC_1754

Alternate gene names: 153935531

Gene position: 1862437-1861553 (Counterclockwise)

Preceding gene: 153937131

Following gene: 153936267

Centisome position: 49.53

GC content: 28.93

Gene sequence:

>885_bases
ATGGAAGAAAACAAACAAGATTTAATGAGAATAATTCAAGTTAAATTTCCAAGATTAAGTAAAGGGCAAAAATTAATAGC
AGAATTTATATTAAAACATTATGATAAAGCTGCTTTTATGACTGCGGCAAAACTTGGAACAAGCGTAGGTGTTAGTGAGT
CTACTGTAGTTAGATTTGCAAATGAGCTTGGATTTACTGGATATCCAAAACTTCAAAAGGCTCTACAAGAACTTATAAAA
AATAAACTTACAACAGTTCAAAGAATAGAACTTTCAAATGATTATGTAAGTGAAGAGTCTGCTTTAAAGGGTGTACTAAA
ATCTGATATGGAAAATATAAGAGCTACTTTAGAAAAAATTAATCATAATACTTTTCAAGATGTAGTGGATAATATATTTG
AAGCTAAAAGAATTTATATTATGGGACTTAGAAGTTCTACTGCTTTAGCAGAGTTTTTAGGATTCTATTTAAATTTAATA
TTAGATAATGTAAATATAATTGCTTATGGAATTAGTGATATTTTTGAACAAATGATAAATGTATCAGAAAATGACTTAGT
TATAGGTATAGGTTTTCCAAGATACGCAGCTAGAACCATAGAAGCACTAACTTTTGCTCAAAATAGAGGAGCAAAGGTTG
TAGCTATAACAGATAGTTTATTATCTCCTTTAGCTGCGAAGGCAGATTATACATTAATAGCCCAAAGTAATATGGCTTCC
TTTGTAGATTCTTTGGTTGCTCCTCTTAGTGTAATAAATGCATTAATTATAGCAGTAGGTTTAAGAGAAAAAGAAAAAAT
ATCTTCAACCTTTAGTACTCTTGAAGGTATTTGGCAAGAATATGAAGTTTATTCTTACAGGGATAATAAAGATAAAAAGT
ACTAA

Upstream 100 bases:

>100_bases
AAACAATTGCATCATCTATTGATAAAGTTTTCAATAGATGATAAACTGAAATAGATAATGCATAATTTTTTTTACCTGTA
AGAAAGGATTTGATTTATAT

Downstream 100 bases:

>100_bases
AATATTCATAAAAAAACTGTTTTTAGAGCTTGTGCAAAAAAGAGGTCATTTTTATACCTCTTTTTTCTGTTTTTTATTAT
TTTTCTAAAAATTTAATTAT

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MEENKQDLMRIIQVKFPRLSKGQKLIAEFILKHYDKAAFMTAAKLGTSVGVSESTVVRFANELGFTGYPKLQKALQELIK
NKLTTVQRIELSNDYVSEESALKGVLKSDMENIRATLEKINHNTFQDVVDNIFEAKRIYIMGLRSSTALAEFLGFYLNLI
LDNVNIIAYGISDIFEQMINVSENDLVIGIGFPRYAARTIEALTFAQNRGAKVVAITDSLLSPLAAKADYTLIAQSNMAS
FVDSLVAPLSVINALIIAVGLREKEKISSTFSTLEGIWQEYEVYSYRDNKDKKY

Sequences:

>Translated_294_residues
MEENKQDLMRIIQVKFPRLSKGQKLIAEFILKHYDKAAFMTAAKLGTSVGVSESTVVRFANELGFTGYPKLQKALQELIK
NKLTTVQRIELSNDYVSEESALKGVLKSDMENIRATLEKINHNTFQDVVDNIFEAKRIYIMGLRSSTALAEFLGFYLNLI
LDNVNIIAYGISDIFEQMINVSENDLVIGIGFPRYAARTIEALTFAQNRGAKVVAITDSLLSPLAAKADYTLIAQSNMAS
FVDSLVAPLSVINALIIAVGLREKEKISSTFSTLEGIWQEYEVYSYRDNKDKKY
>Mature_294_residues
MEENKQDLMRIIQVKFPRLSKGQKLIAEFILKHYDKAAFMTAAKLGTSVGVSESTVVRFANELGFTGYPKLQKALQELIK
NKLTTVQRIELSNDYVSEESALKGVLKSDMENIRATLEKINHNTFQDVVDNIFEAKRIYIMGLRSSTALAEFLGFYLNLI
LDNVNIIAYGISDIFEQMINVSENDLVIGIGFPRYAARTIEALTFAQNRGAKVVAITDSLLSPLAAKADYTLIAQSNMAS
FVDSLVAPLSVINALIIAVGLREKEKISSTFSTLEGIWQEYEVYSYRDNKDKKY

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=291, Percent_Identity=26.8041237113402, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082130, Length=231, Percent_Identity=26.4069264069264, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32963; Mature: 32963

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENKQDLMRIIQVKFPRLSKGQKLIAEFILKHYDKAAFMTAAKLGTSVGVSESTVVRFA
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
NELGFTGYPKLQKALQELIKNKLTTVQRIELSNDYVSEESALKGVLKSDMENIRATLEKI
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NHNTFQDVVDNIFEAKRIYIMGLRSSTALAEFLGFYLNLILDNVNIIAYGISDIFEQMIN
CCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHC
VSENDLVIGIGFPRYAARTIEALTFAQNRGAKVVAITDSLLSPLAAKADYTLIAQSNMAS
CCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCEEEEEHHHHHH
FVDSLVAPLSVINALIIAVGLREKEKISSTFSTLEGIWQEYEVYSYRDNKDKKY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MEENKQDLMRIIQVKFPRLSKGQKLIAEFILKHYDKAAFMTAAKLGTSVGVSESTVVRFA
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
NELGFTGYPKLQKALQELIKNKLTTVQRIELSNDYVSEESALKGVLKSDMENIRATLEKI
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NHNTFQDVVDNIFEAKRIYIMGLRSSTALAEFLGFYLNLILDNVNIIAYGISDIFEQMIN
CCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHC
VSENDLVIGIGFPRYAARTIEALTFAQNRGAKVVAITDSLLSPLAAKADYTLIAQSNMAS
CCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCEEEEEHHHHHH
FVDSLVAPLSVINALIIAVGLREKEKISSTFSTLEGIWQEYEVYSYRDNKDKKY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]