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The map label for this gene is atpD

Identifier: 153931110

GI number: 153931110

Start: 2685515

End: 2686165

Strand: Reverse

Name: atpD

Synonym: CLB_2565

Alternate gene names: 153931110

Gene position: 2686165-2685515 (Counterclockwise)

Preceding gene: 153932485

Following gene: 153933577

Centisome position: 69.53

GC content: 31.03

Gene sequence:

>651_bases
ATGAAATTAAATGTAAATCCTACTAGAATGGAGCTCACTAAACTTAAAAAGAGGTTAACAACAGCCACCAGAGGACATAA
ACTCTTAAAAGATAAGCAAGATGAGCTTATGAGAAGATTCATAGGTATGATAAAAAAGAATAATGAACTTAGAAAAGATG
TAGAAAAGGAATTAGAGGGATCTTTTAAAGACTTTTTAATGGCTAGCGCGGTTATGTCTCCAGAGTTTTTGGAGGAAGCC
GTAGCTTATCCAAAGGAAAGTATTTCTGTAGATGTTAAAAAGCAAAATATAATGAGTGTTAATGTGCCTGTGTTTGACTT
TAAAAGAAAGTTAGAAGGAGATAAAGGAAGTATATTCCCTTATGGTTTTGCTAATACTTCTGCTGAATTAGATGGTGCTA
TAGAAAAATTATATGGTATATTACCTAAGCTTTTAGAATTAGCTAAAGTAGAAAAAGCATGTCAACTAATGGCGGATGAA
ATTGAAAAAACTAGAAGAAGAGTTAACGCTCTAGAATATATGACTATACCTCAACTAGAGGAAACTATAAAATTTATACA
AATGAAGTTAGATGAAAATGAAAGAAGTACAGTAACAAGACTTATGAAAATCAAGAGTATGATGGAAGAAAAGCAAAGTA
ATATGGTATAA

Upstream 100 bases:

>100_bases
AAGTCAGAGCTTAAGAGAATAAGAGATGAATATCTAGAAAAATATTTAAATAAAGCTGAAGAAAGCAAATAATAACCATT
AAAAGGGATGAGTGATCTTT

Downstream 100 bases:

>100_bases
AAAAAGCAGCGAAAATCGCTGCTTTTTTTATACAAAGTAAGTATGTTTTGCTTTAAAATTAATGAGTAGCTATATATGGT
AAAAATAGTTTTAATAAAAT

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKELEGSFKDFLMASAVMSPEFLEEA
VAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGSIFPYGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLMADE
IEKTRRRVNALEYMTIPQLEETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV

Sequences:

>Translated_216_residues
MKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKELEGSFKDFLMASAVMSPEFLEEA
VAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGSIFPYGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLMADE
IEKTRRRVNALEYMTIPQLEETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV
>Mature_216_residues
MKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKELEGSFKDFLMASAVMSPEFLEEA
VAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGSIFPYGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLMADE
IEKTRRRVNALEYMTIPQLEETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family

Homologues:

Organism=Homo sapiens, GI7706757, Length=207, Percent_Identity=31.4009661835749, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17553636, Length=211, Percent_Identity=32.7014218009479, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320784, Length=207, Percent_Identity=28.0193236714976, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20128937, Length=217, Percent_Identity=31.7972350230415, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21355551, Length=209, Percent_Identity=33.0143540669856, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATD_CLOB1 (A7FWQ5)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001384866.1
- STRING:   A7FWQ5
- GeneID:   5396108
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_2565
- eggNOG:   COG1394
- HOGENOM:   HBG732046
- OMA:   GEVMKEA
- ProtClustDB:   PRK00373
- BioCyc:   CBOT441770:CLB_2565-MONOMER
- HAMAP:   MF_00271
- InterPro:   IPR002699
- PANTHER:   PTHR11671
- TIGRFAMs:   TIGR00309

Pfam domain/function: PF01813 ATP-synt_D

EC number: 3.6.3.14

Molecular weight: Translated: 25004; Mature: 25004

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKELEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SFKDFLMASAVMSPEFLEEAVAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGSIFP
HHHHHHHHHHHCCHHHHHHHHHCCHHHCEEEEECCCEEECCCCHHHHHHHHCCCCCCCCC
YGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLMADEIEKTRRRVNALEYMTIPQLE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLNVNPTRMELTKLKKRLTTATRGHKLLKDKQDELMRRFIGMIKKNNELRKDVEKELEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SFKDFLMASAVMSPEFLEEAVAYPKESISVDVKKQNIMSVNVPVFDFKRKLEGDKGSIFP
HHHHHHHHHHHCCHHHHHHHHHCCHHHCEEEEECCCEEECCCCHHHHHHHHCCCCCCCCC
YGFANTSAELDGAIEKLYGILPKLLELAKVEKACQLMADEIEKTRRRVNALEYMTIPQLE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ETIKFIQMKLDENERSTVTRLMKIKSMMEEKQSNMV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA