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The map label for this gene is comFA [H]

Identifier: 152977402

GI number: 152977402

Start: 3785689

End: 3787038

Strand: Reverse

Name: comFA [H]

Synonym: Bcer98_3730

Alternate gene names: 152977402

Gene position: 3787038-3785689 (Counterclockwise)

Preceding gene: 152977403

Following gene: 152977401

Centisome position: 92.66

GC content: 38.37

Gene sequence:

>1350_bases
ATGATACAAAAAGGAAGACAAATGTTATTGCATGAACTTTCATGGTCAAAAGAACAGTTGCACGATTTCATAAGTAGAGG
GGAGATTGTATTAGAAAAAGGGATTGTTCGAAAAAGTTCCAATTATATATGCCAACGTTGCGGGAATCAAGAGAAACGTC
TATTTGCATCATTTTTATGCAAAAGGTGTAATCAAGTATGTGCGTATTGCCGGAAGTGTATTATGATGGGACGAGTAAGC
GAATGTACGATGCTTGTTCGAAGTGTTTGCGAAGGGAAACAAGAATGTTTTCCTCATGCCTTGCAGTGGAAAGGAGTATT
GTCACCGGGGCAAAATAGGGCTGCAAAAGGGGTAGTAGAAGCAATTAAACAGAAAGAGTCCTTTTTTATTTGGGCGGTAT
GTGGTGCTGGAAAAACGGAGATGTTGTTTTCTGGCATAGATGAAGCGCTTAAAAACGGTAAGCGAGTTTGTATAGCGACG
CCTCGAAAAGATGTTGTATTAGAATTAGCTCCACGACTACAAGAAGTGTTTCCAGATATACCATTTGCGACATTATACGG
AGGCAGTAAAGAATATGAAAAAGAAGCGATGCTTATCGTAACTACAACTCATCAGTTGCTTCGCTATTATAGGGCGTTTG
ATGTCATGATTATAGATGAAATTGATGCTTTTCCGTATGCGATGGATCATATGTTACATGAGGCCGTAAGAAAAGCGGCG
AAGGAGGATGCTTCCTATATTTATTTAACAGCAACTCCAGAAGAGAAATGGAAACAGAGTGTGCAAAATGGTAAACAAAA
AGGTGTTATTATATCAGGACGTTATCATCGCCATCCATTACCGGTTCCTAAATTAAAATGGTGTGGAAATTGGAGAAAAC
TACTTCGACGTAAACAAATTCCTCAAGTTCTATTGGACTGGCTTCTTATATATCTACAAAAACATTATCCTATCTTTTTA
TTTGTTCCTCATATTTGTTATGTAGAGGAAGTAACGGCTGTGTTACAAAGATTACATCATAAAATTGCTGGTGTTCATGC
AGAAGATCCAATGAGAAAAGAGAAAGTAGAGGCATTTCGTAAAGGGGATATACCACTACTCATAACTACAACTATATTGG
AGAGAGGGGTAACGGTCACGAATTTACAAGTAGCTGTGCTAGGAGCAGAAGAGGATATTTTTTCTGAAAGTGCACTGGTT
CAGATAGCGGGCCGCGTTGGTAGAAGTTCTCACAATCCAAAGGGGGAAGTCATTTATTTTCATTATGGAAAAACGAAAGC
AATGACTGCTGCGAAAAAGCATATTCAATTTATGAATAAAAGGGCTAAACAAGAAGGGTTGATAGATTGA

Upstream 100 bases:

>100_bases
ATAAAGTCGATAGCTTACTATTTTATAAGTAGGTTATCGGCTTTTTTGATTTTTTACAGTGTTACGACAAGGAAGTAAAG
TAGAGAAGGGGGGATGTCTA

Downstream 100 bases:

>100_bases
TGCACTGTTTACTTTGTGACGATTATATTGCCGAAGAAGCGAGTTGGTATTCTTTTTTTATTCGGTCTCACGATAGATAC
ATATGCAATCTATGTGAACG

Product: helicase domain-containing protein

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MIQKGRQMLLHELSWSKEQLHDFISRGEIVLEKGIVRKSSNYICQRCGNQEKRLFASFLCKRCNQVCAYCRKCIMMGRVS
ECTMLVRSVCEGKQECFPHALQWKGVLSPGQNRAAKGVVEAIKQKESFFIWAVCGAGKTEMLFSGIDEALKNGKRVCIAT
PRKDVVLELAPRLQEVFPDIPFATLYGGSKEYEKEAMLIVTTTHQLLRYYRAFDVMIIDEIDAFPYAMDHMLHEAVRKAA
KEDASYIYLTATPEEKWKQSVQNGKQKGVIISGRYHRHPLPVPKLKWCGNWRKLLRRKQIPQVLLDWLLIYLQKHYPIFL
FVPHICYVEEVTAVLQRLHHKIAGVHAEDPMRKEKVEAFRKGDIPLLITTTILERGVTVTNLQVAVLGAEEDIFSESALV
QIAGRVGRSSHNPKGEVIYFHYGKTKAMTAAKKHIQFMNKRAKQEGLID

Sequences:

>Translated_449_residues
MIQKGRQMLLHELSWSKEQLHDFISRGEIVLEKGIVRKSSNYICQRCGNQEKRLFASFLCKRCNQVCAYCRKCIMMGRVS
ECTMLVRSVCEGKQECFPHALQWKGVLSPGQNRAAKGVVEAIKQKESFFIWAVCGAGKTEMLFSGIDEALKNGKRVCIAT
PRKDVVLELAPRLQEVFPDIPFATLYGGSKEYEKEAMLIVTTTHQLLRYYRAFDVMIIDEIDAFPYAMDHMLHEAVRKAA
KEDASYIYLTATPEEKWKQSVQNGKQKGVIISGRYHRHPLPVPKLKWCGNWRKLLRRKQIPQVLLDWLLIYLQKHYPIFL
FVPHICYVEEVTAVLQRLHHKIAGVHAEDPMRKEKVEAFRKGDIPLLITTTILERGVTVTNLQVAVLGAEEDIFSESALV
QIAGRVGRSSHNPKGEVIYFHYGKTKAMTAAKKHIQFMNKRAKQEGLID
>Mature_449_residues
MIQKGRQMLLHELSWSKEQLHDFISRGEIVLEKGIVRKSSNYICQRCGNQEKRLFASFLCKRCNQVCAYCRKCIMMGRVS
ECTMLVRSVCEGKQECFPHALQWKGVLSPGQNRAAKGVVEAIKQKESFFIWAVCGAGKTEMLFSGIDEALKNGKRVCIAT
PRKDVVLELAPRLQEVFPDIPFATLYGGSKEYEKEAMLIVTTTHQLLRYYRAFDVMIIDEIDAFPYAMDHMLHEAVRKAA
KEDASYIYLTATPEEKWKQSVQNGKQKGVIISGRYHRHPLPVPKLKWCGNWRKLLRRKQIPQVLLDWLLIYLQKHYPIFL
FVPHICYVEEVTAVLQRLHHKIAGVHAEDPMRKEKVEAFRKGDIPLLITTTILERGVTVTNLQVAVLGAEEDIFSESALV
QIAGRVGRSSHNPKGEVIYFHYGKTKAMTAAKKHIQFMNKRAKQEGLID

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 51448; Mature: 51448

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQKGRQMLLHELSWSKEQLHDFISRGEIVLEKGIVRKSSNYICQRCGNQEKRLFASFLC
CCCCHHHHHHHHHCCCHHHHHHHHHCCCEEEHHCHHHCCCHHHHHHCCCHHHHHHHHHHH
KRCNQVCAYCRKCIMMGRVSECTMLVRSVCEGKQECFPHALQWKGVLSPGQNRAAKGVVE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHHCCCCCCCCCCHHHHHHHH
AIKQKESFFIWAVCGAGKTEMLFSGIDEALKNGKRVCIATPRKDVVLELAPRLQEVFPDI
HHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCC
PFATLYGGSKEYEKEAMLIVTTTHQLLRYYRAFDVMIIDEIDAFPYAMDHMLHEAVRKAA
CEEEECCCCCHHCCCEEEEEECHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHH
KEDASYIYLTATPEEKWKQSVQNGKQKGVIISGRYHRHPLPVPKLKWCGNWRKLLRRKQI
HCCCCEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCC
PQVLLDWLLIYLQKHYPIFLFVPHICYVEEVTAVLQRLHHKIAGVHAEDPMRKEKVEAFR
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
KGDIPLLITTTILERGVTVTNLQVAVLGAEEDIFSESALVQIAGRVGRSSHNPKGEVIYF
CCCCCEEEEHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
HYGKTKAMTAAKKHIQFMNKRAKQEGLID
EECCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIQKGRQMLLHELSWSKEQLHDFISRGEIVLEKGIVRKSSNYICQRCGNQEKRLFASFLC
CCCCHHHHHHHHHCCCHHHHHHHHHCCCEEEHHCHHHCCCHHHHHHCCCHHHHHHHHHHH
KRCNQVCAYCRKCIMMGRVSECTMLVRSVCEGKQECFPHALQWKGVLSPGQNRAAKGVVE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHHCCCCCCCCCCHHHHHHHH
AIKQKESFFIWAVCGAGKTEMLFSGIDEALKNGKRVCIATPRKDVVLELAPRLQEVFPDI
HHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCC
PFATLYGGSKEYEKEAMLIVTTTHQLLRYYRAFDVMIIDEIDAFPYAMDHMLHEAVRKAA
CEEEECCCCCHHCCCEEEEEECHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHH
KEDASYIYLTATPEEKWKQSVQNGKQKGVIISGRYHRHPLPVPKLKWCGNWRKLLRRKQI
HCCCCEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCC
PQVLLDWLLIYLQKHYPIFLFVPHICYVEEVTAVLQRLHHKIAGVHAEDPMRKEKVEAFR
HHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
KGDIPLLITTTILERGVTVTNLQVAVLGAEEDIFSESALVQIAGRVGRSSHNPKGEVIYF
CCCCCEEEEHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
HYGKTKAMTAAKKHIQFMNKRAKQEGLID
EECCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]