Click here to switch to the map view.

The map label for this gene is lytF [H]

Identifier: 152977403

GI number: 152977403

Start: 3787164

End: 3788393

Strand: Reverse

Name: lytF [H]

Synonym: Bcer98_3731

Alternate gene names: 152977403

Gene position: 3788393-3787164 (Counterclockwise)

Preceding gene: 152977404

Following gene: 152977402

Centisome position: 92.69

GC content: 36.59

Gene sequence:

>1230_bases
ATGAAAAAGCTAAAGATGGCATCTTGCGCATTGGCTGCAGGAATGATGTTTTCAGTGGTAGCACCAAATGTATTCGCAGA
AAAGATTGATGACGTAAAAACACAAATTAATGCACAAAATGATACTTTACATAAACAACAACAAGAACGTGATGAGCTTC
AAAAGCAAATGAATGACTTAAATAAAACGATTCAAAACTTAGATAAGTCTGTTCAAGAGAATACAGCGAAGCTTGATGAA
ACAACAAAAAAAGTTGCTGAAACAGAGCAATTAATTGAGGAGAAAAGTAAGCATATTGCTGAGTTACAAACAAAGATTTC
TAAACGTGAAGAATTGCTGAGAAAACGTTTAGTAGCACTTCAAGAACAACCAAATACGAACGTTGTAGCAGAGGTTGTTG
TGAACTCTAAGAACATTGCTGATTTAGTAGATCGTTTAACTTCAGTTTCTAAAATTTTTGAATCTGATGAAGATATTATG
AAAACGCAACAAAGCGATCAAGAAGCTGTGAAAAGAGACGTTGAAACAGTTAAGCAAAAGCAAAAAGAGCTGAAAGAAGC
ACAATCAAAAATTGAAGCAGCAAAGAAAGAGCTTGATGCTGAAAAAGCAAAAAAACAAGAAGCGGTAAATGAATTAAGTG
CTAAAATGGACACTGTTGTAAAAAATATGACAAGTACAGAAGGTCAATTAAAAGAGCTTGAAAAGCAAGCGTTATATTTA
CAACAATTAGCTGAAAAAGAAGAACAAGAAAAAGAAAAGGCTGCACAAGAAGCGGCTGCTCAAAAACAAGTAGCAGAGGC
TCAAACACAACAAGCAGCTCCGCAAGAACAGCCTAAAAAAGAACCGAAAAAATCAGCTCCAACTCCTGCGCAAAACCCAG
CTCCAGCTCCTGGTGTAATTGGTAAAGCACAGCAATATTTAGGTATGCCATACGTTTGGGGAAGTGCATCTCCATCAAAC
GGTGGTTTTGACTGCAGTGGTTTCATCTCTTATGTTTATGGAGTAGGTCGTCAAGATGTTGCTGGTTACTGGAACTCTGT
TTCTAAAGTAAGCAGTCCACAACCAGGAGATTTAGTATTCTTCCAAGGTACTTACAAAGCAGGTCCATCTCACATTGGTA
TTTATGTTGGTAATGGACAAATGATTCATGCTGGTGATAAAGGTATTGCATACTCTAGCTTAAGCAGCAGTTACAATCAA
AAACATTTCTTAGGTTATGGTAGATTCTAA

Upstream 100 bases:

>100_bases
CATTTATTTTACAAAAACGTAACATTGACAAAAAAACTGCCGAATTATGGTATAAGTTTTAATAGATTATATTCGGAAAA
GAAAGCGGTGTAAAAACAAA

Downstream 100 bases:

>100_bases
GATTTGTAACATATAAAACATGTGTATAAAGTCGATAGCTTACTATTTTATAAGTAGGTTATCGGCTTTTTTGATTTTTT
ACAGTGTTACGACAAGGAAG

Product: NLP/P60 protein

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP49; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytF [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MKKLKMASCALAAGMMFSVVAPNVFAEKIDDVKTQINAQNDTLHKQQQERDELQKQMNDLNKTIQNLDKSVQENTAKLDE
TTKKVAETEQLIEEKSKHIAELQTKISKREELLRKRLVALQEQPNTNVVAEVVVNSKNIADLVDRLTSVSKIFESDEDIM
KTQQSDQEAVKRDVETVKQKQKELKEAQSKIEAAKKELDAEKAKKQEAVNELSAKMDTVVKNMTSTEGQLKELEKQALYL
QQLAEKEEQEKEKAAQEAAAQKQVAEAQTQQAAPQEQPKKEPKKSAPTPAQNPAPAPGVIGKAQQYLGMPYVWGSASPSN
GGFDCSGFISYVYGVGRQDVAGYWNSVSKVSSPQPGDLVFFQGTYKAGPSHIGIYVGNGQMIHAGDKGIAYSSLSSSYNQ
KHFLGYGRF

Sequences:

>Translated_409_residues
MKKLKMASCALAAGMMFSVVAPNVFAEKIDDVKTQINAQNDTLHKQQQERDELQKQMNDLNKTIQNLDKSVQENTAKLDE
TTKKVAETEQLIEEKSKHIAELQTKISKREELLRKRLVALQEQPNTNVVAEVVVNSKNIADLVDRLTSVSKIFESDEDIM
KTQQSDQEAVKRDVETVKQKQKELKEAQSKIEAAKKELDAEKAKKQEAVNELSAKMDTVVKNMTSTEGQLKELEKQALYL
QQLAEKEEQEKEKAAQEAAAQKQVAEAQTQQAAPQEQPKKEPKKSAPTPAQNPAPAPGVIGKAQQYLGMPYVWGSASPSN
GGFDCSGFISYVYGVGRQDVAGYWNSVSKVSSPQPGDLVFFQGTYKAGPSHIGIYVGNGQMIHAGDKGIAYSSLSSSYNQ
KHFLGYGRF
>Mature_409_residues
MKKLKMASCALAAGMMFSVVAPNVFAEKIDDVKTQINAQNDTLHKQQQERDELQKQMNDLNKTIQNLDKSVQENTAKLDE
TTKKVAETEQLIEEKSKHIAELQTKISKREELLRKRLVALQEQPNTNVVAEVVVNSKNIADLVDRLTSVSKIFESDEDIM
KTQQSDQEAVKRDVETVKQKQKELKEAQSKIEAAKKELDAEKAKKQEAVNELSAKMDTVVKNMTSTEGQLKELEKQALYL
QQLAEKEEQEKEKAAQEAAAQKQVAEAQTQQAAPQEQPKKEPKKSAPTPAQNPAPAPGVIGKAQQYLGMPYVWGSASPSN
GGFDCSGFISYVYGVGRQDVAGYWNSVSKVSSPQPGDLVFFQGTYKAGPSHIGIYVGNGQMIHAGDKGIAYSSLSSSYNQ
KHFLGYGRF

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=120, Percent_Identity=35.8333333333333, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786421, Length=120, Percent_Identity=35, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 45270; Mature: 45270

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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ECCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHCCCCHHCCCCCCC
>Mature Secondary Structure
MKKLKMASCALAAGMMFSVVAPNVFAEKIDDVKTQINAQNDTLHKQQQERDELQKQMNDL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
NKTIQNLDKSVQENTAKLDETTKKVAETEQLIEEKSKHIAELQTKISKREELLRKRLVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEQPNTNVVAEVVVNSKNIADLVDRLTSVSKIFESDEDIMKTQQSDQEAVKRDVETVKQK
HCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHH
QKELKEAQSKIEAAKKELDAEKAKKQEAVNELSAKMDTVVKNMTSTEGQLKELEKQALYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QQLAEKEEQEKEKAAQEAAAQKQVAEAQTQQAAPQEQPKKEPKKSAPTPAQNPAPAPGVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCHH
GKAQQYLGMPYVWGSASPSNGGFDCSGFISYVYGVGRQDVAGYWNSVSKVSSPQPGDLVF
HHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEE
FQGTYKAGPSHIGIYVGNGQMIHAGDKGIAYSSLSSSYNQKHFLGYGRF
ECCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10206711 [H]