Click here to switch to the map view.

The map label for this gene is tpiA [H]

Identifier: 152977355

GI number: 152977355

Start: 3740082

End: 3740837

Strand: Reverse

Name: tpiA [H]

Synonym: Bcer98_3680

Alternate gene names: 152977355

Gene position: 3740837-3740082 (Counterclockwise)

Preceding gene: 152977356

Following gene: 152977354

Centisome position: 91.53

GC content: 42.2

Gene sequence:

>756_bases
ATGCGTAAACCAATTATCGCAGGTAACTGGAAAATGAATAAAACTCTATCTGAAGCAGTTAGCTTCGTAGAAGAAGTAAA
AGGTCAAATTCCAGCAGCTTCAGCTGTTGATGCAGTTGTTTGCTCTCCAGCTCTATTCTTAGAGCGTTTAGTAGCAGCGA
CGCAAGGAACTGACTTAAAAGTAGGTGCACAAAACATGCACTTCGAAAAAAATGGTGCATTCACTGGTGAGATTAGCCCA
GTAGCACTTAGCGACTTAAAAGTGAGCTACGTAGTACTTGGTCACTCTGAACGTCGTGAAATGTTTGCTGAAACAGATGA
AACAGTAAATAAAAAAACACTTGCAGCATTTGAACATGGTTTAACACCAATCGTTTGCTGTGGTGAAACTTTAGAAGAAC
GTGAAAGCGGAAAAACATTTGATCTAGTAGCAGGCCAAGTGACAAAAGCACTTGCAGGCTTAACAGAAGAACAAGTGAAA
GCTACTGTTATCGCATATGAGCCAATTTGGGCAATCGGTACAGGAAAATCTTCTTCTGCAGAAGATGCAAACGAAGTATG
TGCACACATCCGTAAAGTTGTTGCAGAAGCTGTTTCTCCAGCAGCTGCAGAAGCTGTTCGTATTCAATACGGCGGTAGCG
TAAAACCAGGAAACATTAAAGAATACATGGCACAACCTGACATCGACGGCGCTTTAGTTGGCGGTGCAAGTTTAGAGCCA
GCTTCCTTCTTAGGTCTTTTGGAGGCGGTAAAATGA

Upstream 100 bases:

>100_bases
CGGTGCGTCATTAGAATTTATGGAAGGTAAAGAACTTCCAGGTGTAGTTTGTCTGAATGACAAATAATTAGCAGCCAAAG
AAAAAAGGACGGTGCAAAGC

Downstream 100 bases:

>100_bases
GAAAGCCAACAGCTTTAATCATTCTTGACGGTTTCGGACTGCGTGAAGAAACTTACGGGAATGCTGTAGCACAAGCTAAG
AAACCTAATTTTGATAGATA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATQGTDLKVGAQNMHFEKNGAFTGEISP
VALSDLKVSYVVLGHSERREMFAETDETVNKKTLAAFEHGLTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVK
ATVIAYEPIWAIGTGKSSSAEDANEVCAHIRKVVAEAVSPAAAEAVRIQYGGSVKPGNIKEYMAQPDIDGALVGGASLEP
ASFLGLLEAVK

Sequences:

>Translated_251_residues
MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATQGTDLKVGAQNMHFEKNGAFTGEISP
VALSDLKVSYVVLGHSERREMFAETDETVNKKTLAAFEHGLTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVK
ATVIAYEPIWAIGTGKSSSAEDANEVCAHIRKVVAEAVSPAAAEAVRIQYGGSVKPGNIKEYMAQPDIDGALVGGASLEP
ASFLGLLEAVK
>Mature_251_residues
MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATQGTDLKVGAQNMHFEKNGAFTGEISP
VALSDLKVSYVVLGHSERREMFAETDETVNKKTLAAFEHGLTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVK
ATVIAYEPIWAIGTGKSSSAEDANEVCAHIRKVVAEAVSPAAAEAVRIQYGGSVKPGNIKEYMAQPDIDGALVGGASLEP
ASFLGLLEAVK

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=251, Percent_Identity=43.4262948207171, Blast_Score=183, Evalue=1e-46,
Organism=Homo sapiens, GI226529917, Length=251, Percent_Identity=43.4262948207171, Blast_Score=183, Evalue=1e-46,
Organism=Escherichia coli, GI1790353, Length=249, Percent_Identity=40.9638554216867, Blast_Score=196, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17536593, Length=253, Percent_Identity=45.8498023715415, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320255, Length=243, Percent_Identity=41.5637860082305, Blast_Score=180, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28572008, Length=250, Percent_Identity=42.4, Blast_Score=183, Evalue=9e-47,
Organism=Drosophila melanogaster, GI28572006, Length=250, Percent_Identity=42.4, Blast_Score=183, Evalue=9e-47,
Organism=Drosophila melanogaster, GI28572004, Length=250, Percent_Identity=42.4, Blast_Score=182, Evalue=1e-46,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 26505; Mature: 26505

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATQGTDLK
CCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VGAQNMHFEKNGAFTGEISPVALSDLKVSYVVLGHSERREMFAETDETVNKKTLAAFEHG
ECCCCCEEECCCCCCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
LTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVKATVIAYEPIWAIGTGKSSSA
CCEEEECCHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHHEEEEEEECCEEEEECCCCCCC
EDANEVCAHIRKVVAEAVSPAAAEAVRIQYGGSVKPGNIKEYMAQPDIDGALVGGASLEP
CCHHHHHHHHHHHHHHHHCCHHHHEEEEEECCCCCCCCHHHHHCCCCCCCEEECCCCCCH
ASFLGLLEAVK
HHHHHHHHHCC
>Mature Secondary Structure
MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATQGTDLK
CCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VGAQNMHFEKNGAFTGEISPVALSDLKVSYVVLGHSERREMFAETDETVNKKTLAAFEHG
ECCCCCEEECCCCCCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
LTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVKATVIAYEPIWAIGTGKSSSA
CCEEEECCHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHHEEEEEEECCEEEEECCCCCCC
EDANEVCAHIRKVVAEAVSPAAAEAVRIQYGGSVKPGNIKEYMAQPDIDGALVGGASLEP
CCHHHHHHHHHHHHHHHHCCHHHHEEEEEECCCCCCCCHHHHHCCCCCCCEEECCCCCCH
ASFLGLLEAVK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]