Click here to switch to the map view.

The map label for this gene is est [H]

Identifier: 152977349

GI number: 152977349

Start: 3734652

End: 3735395

Strand: Reverse

Name: est [H]

Synonym: Bcer98_3674

Alternate gene names: 152977349

Gene position: 3735395-3734652 (Counterclockwise)

Preceding gene: 152977350

Following gene: 152977348

Centisome position: 91.4

GC content: 38.44

Gene sequence:

>744_bases
ATGATGAAATTAGCATCTCCGAAACCATTTACATTTGAAGGTGGAGACCGCGCTGTTTTATTATTGCACGGTTTCACGGG
AAACTCAGCTGATGTACGTATGTTAGGGCGTTTCTTAGAGAAAAAAGGATACACTTGCCACGCCCCTATTTATAAAGGCC
ATGGTGTGCCACCAGAACAGCTTGTACATACAGGTCCTGAAGACTGGTGGAAAGATGTAATGAACGCGTATCAGCATTTA
AAAGATCAAGGCTATGAGAAGATTGCTGCTGTTGGATTGTCACTTGGTGGTGTATTCTCATTAAAGCTTGCTTATACAGT
TCCTATTTTAGGTGTAGTACCAATGTGTGCGCCAATGTATATTAAGAGTGAAGAAACAATGTACCAAGGTATATTGGCAT
ATGCGCGTGAATATAAAAAACGTGAACAGAAGTCGCCAGAGCAAATTGAACAAGAGATGTTCGAATTTAAAAAGACACCA
ATGAATACATTAAAGGCATTACAAGATTTAATTCGTGACGTACGCAATAATGTAGATATGATTTATGCACCAACATTTGT
TGTACAAGCGCGCCATGATGAAATGATTAATACTGACAGCGCAAACATTATTTATAACGGTGTAGAATCTACATTAAAAG
AGATCAAATGGTATGAAGACTCTACTCACGTCATTACGCTGGATAAACAACGTGATGAGCTACATGAAGACGTATATAAC
TTCTTGGAGCAACTAGATTGGTAA

Upstream 100 bases:

>100_bases
ATGTAAACAAAGTTTCAAATTAGATTATGGAAATAGAACTATGGTAAACTAAGGACAGAAACAATACGACTAGACTACAG
AAGAGAAAGAGGAGAAGAAG

Downstream 100 bases:

>100_bases
GATCTAGTTGCCTCTTTTTTTCATGGGGGCTGTAAGGTAGAAGGAATCGCAAGATAAAGGATGAAAAATGAATGTTTGTA
GAAGTTTCACTTTATATATC

Product: carboxylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEQLVHTGPEDWWKDVMNAYQHL
KDQGYEKIAAVGLSLGGVFSLKLAYTVPILGVVPMCAPMYIKSEETMYQGILAYAREYKKREQKSPEQIEQEMFEFKKTP
MNTLKALQDLIRDVRNNVDMIYAPTFVVQARHDEMINTDSANIIYNGVESTLKEIKWYEDSTHVITLDKQRDELHEDVYN
FLEQLDW

Sequences:

>Translated_247_residues
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEQLVHTGPEDWWKDVMNAYQHL
KDQGYEKIAAVGLSLGGVFSLKLAYTVPILGVVPMCAPMYIKSEETMYQGILAYAREYKKREQKSPEQIEQEMFEFKKTP
MNTLKALQDLIRDVRNNVDMIYAPTFVVQARHDEMINTDSANIIYNGVESTLKEIKWYEDSTHVITLDKQRDELHEDVYN
FLEQLDW
>Mature_247_residues
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEQLVHTGPEDWWKDVMNAYQHL
KDQGYEKIAAVGLSLGGVFSLKLAYTVPILGVVPMCAPMYIKSEETMYQGILAYAREYKKREQKSPEQIEQEMFEFKKTP
MNTLKALQDLIRDVRNNVDMIYAPTFVVQARHDEMINTDSANIIYNGVESTLKEIKWYEDSTHVITLDKQRDELHEDVYN
FLEQLDW

Specific function: Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012354
- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 28430; Mature: 28430

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEQ
CCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHH
LVHTGPEDWWKDVMNAYQHLKDQGYEKIAAVGLSLGGVFSLKLAYTVPILGVVPMCAPMY
HHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCE
IKSEETMYQGILAYAREYKKREQKSPEQIEQEMFEFKKTPMNTLKALQDLIRDVRNNVDM
ECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCE
IYAPTFVVQARHDEMINTDSANIIYNGVESTLKEIKWYEDSTHVITLDKQRDELHEDVYN
EEECCEEEEECCCHHCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
FLEQLDW
HHHHHCC
>Mature Secondary Structure
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEQ
CCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHH
LVHTGPEDWWKDVMNAYQHLKDQGYEKIAAVGLSLGGVFSLKLAYTVPILGVVPMCAPMY
HHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCE
IKSEETMYQGILAYAREYKKREQKSPEQIEQEMFEFKKTPMNTLKALQDLIRDVRNNVDM
ECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCE
IYAPTFVVQARHDEMINTDSANIIYNGVESTLKEIKWYEDSTHVITLDKQRDELHEDVYN
EEECCEEEEECCCHHCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
FLEQLDW
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1369099 [H]