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The map label for this gene is rnr [H]

Identifier: 152977348

GI number: 152977348

Start: 3732119

End: 3734497

Strand: Reverse

Name: rnr [H]

Synonym: Bcer98_3673

Alternate gene names: 152977348

Gene position: 3734497-3732119 (Counterclockwise)

Preceding gene: 152977349

Following gene: 152977347

Centisome position: 91.37

GC content: 40.23

Gene sequence:

>2379_bases
TTGGAAGATATCATTCAAGAACATATTGATAAGTTGTTATTATTTATGAAAGAAGAAGCGTATAAACCGCTAACGATACA
AGAATTAGAGGCTGCCTTTGGAATTGAAGATTCCGCAGGATTTAAAGATTTTGTAAAAGCGCTTGTTATGATGGAAGAAA
CGGGACTTGTTGTGCGTACGCGCAGTAATCGCTACGGTCTTCCAGAAAAAATGAATTTAGTGCGCGGGAAATTAATTGGA
CATGCACGTGGCTTTGCATTCGTTGTTCCAGAAGAGAAGAAAACGGGAGACGATGATCTTTTCATTCCGCCGACAGAATT
AAACGGTGCACTTCATGGAGACACAGTATTAGCACGAATTAGCTCACAATCTAGCGGGTCACGTCAAGAAGGTACGATTA
TTCGTATTGTGGAGCGCGGAACGAAAGAATTAGTTGGTACATATACAGAATCAAAAAATTTCGGGTTTGTTATTCCAGAC
AATAAAAGATGGACAAGCGATATTTTTATCCCGAAAAGCGCCTCTATGGGTGCTGTTGAAGGTCATAAAGTAGTTGTGAA
AATTACTAGCTATCCGCAAAATCGTTTAAGTGCAGAGGGCGAAGTCATTCAAATTTTAGGACATAAAAATGATCCAGGAG
TAGATATTTTATCGGTTATTCATAAACATCATTTGCCTTTAGCGTTTCCAGAAGAAGTAATGGAGCACGCGAACAGTGTA
CCAGAAACAATTTCAGAAGAAGATTTAAAGGATCGCCGTGATTTGCGTGACCAAATGATTGTGACAATCGATGGTGCAGA
TGCGAAAGATTTAGATGATGCAGTTACAGTCACGAAGCTTGAGAACGGTAATTATAAGCTAGGTGTTCATATTGCAGATG
TGAGTCACTATGTTCATGAAGGCTCTCCAATTGATGTAGAAGCAGCAGAGAGGGCGACAAGTGTCTATCTTGTAGATCGT
GTAATTCCAATGATTCCGCATCGTTTATCAAATGGAATTTGCTCATTAAATCCAAAAGTAGATCGTTTAACATTATCTTG
TGAAATGGAAATTAACCATTTAGGCGATGTTGTAAAACATGAAATTTTCCAAAGTGTAATCAAGACGACAGAACGCATGA
CATATGCTGATGTAAGAAGCATTTTGGAAGATGAAGATGAAGAATTAATGGAACGTTATAAGCCACTTGTTCCAATGTTT
AAAGAGATGGCAGAATTAGCGCAAATTTTACGTGAAAAACGTATGAGACGCGGCGCTATTGACTTTGATTTCAAAGAAGC
GAAAGTATTAGTTGATGAAGAAGGAAAGCCGACAGATGTTGTGCTGCGCGATCGCTCAATATCTGAAAAGCTCATTGAAG
AATTTATGCTTGTTGCAAACGAAACAGTGGCAGAGCATTTTCACTGGATGAATGTACCGTTTATGTACCGTATTCATGAA
GAGCCGAAAGAAGATAAATTAGAACGTTTCTTCGAGTTCGTTACAAACTTCGGATACGCGGTAAAAGGACGTGCCAATGA
GGTGCATCCTCGTGCTTTACAGCAAATTCTGGAAATGGTGCAAGGTCAGCCAGAAGAACCAGTTATTTCAACAGTTATGC
TTCGCTCGATGAAGCAAGCTCGTTATGATGCTGAAAGCTTAGGACATTTCGGTCTATCAACAGAATTCTATACACATTTC
ACCTCGCCAATTCGTCGTTATCCAGATACGATTGTTCACAGGCTGATTCGTGAATATATCATTAATGGCAATATAGACAA
TGAAACACAAGCAAAGTGGCATGAGAAGTTACCAGATATCGCAGAGCATTCGTCCAATATGGAACGCCGCGCTGTTGAAG
CGGAACGCGAAACAGATGAACTGAAAAAGGCAGAGTATATGCTTGATAAGATTGGTGAAGAGTATGATGGTATGATTAGC
TCTGTAACGAACTTTGGTTTATTTGTAGAGCTTCCAAACACAATTGAAGGTCTCGTTCATGTTAGTTATTTAACAGATGA
TTACTACCGTTATGATGAACAGCACTTTGCGATGATTGGTGAGCGCACAGGTAACGTCTTCCGCATCGGTGATGAAATTA
CAATTCGCGTGATTAATGTCAATAAAGATGAGCGCGCAATTGATTTTGAAATCGTCGGTATGAAAGGCACGCCAAGACGT
AAACTCAAAGACCGTCCAATTGTCATTGAACAACCAAAAGGTGGCAGAAAGAAACGTAGTGGCCGTGGTAGTGACGAGCG
CGGAAAAGATCGCAAACATGAGCGCGGCAGCCGCGGAAAAGGCAGAGCGGATCACTCTGGAAAAAAAGGTGGCAAAAAGA
AAAAGCCATTCTTTGAGAACGTTCCAGGATTCAAGAAGAAAAAGAAAAAGCGTAAGTAA

Upstream 100 bases:

>100_bases
TAAAGGATGAAAAATGAATGTTTGTAGAAGTTTCACTTTATATATCCCACATCTTTCGGATACACTAGACAATATGAGGG
TTTAAAGGAGGTATTTGTGC

Downstream 100 bases:

>100_bases
GGGATGGCTTCGCTTTTAATAAAGCGGAGCCATTTTTATTTTTTTTATAATCTAGCTCCAGTGGCTTTGCTTCTTCTCAC
ATTCCGAGCGAGCCACTTCC

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MEDIIQEHIDKLLLFMKEEAYKPLTIQELEAAFGIEDSAGFKDFVKALVMMEETGLVVRTRSNRYGLPEKMNLVRGKLIG
HARGFAFVVPEEKKTGDDDLFIPPTELNGALHGDTVLARISSQSSGSRQEGTIIRIVERGTKELVGTYTESKNFGFVIPD
NKRWTSDIFIPKSASMGAVEGHKVVVKITSYPQNRLSAEGEVIQILGHKNDPGVDILSVIHKHHLPLAFPEEVMEHANSV
PETISEEDLKDRRDLRDQMIVTIDGADAKDLDDAVTVTKLENGNYKLGVHIADVSHYVHEGSPIDVEAAERATSVYLVDR
VIPMIPHRLSNGICSLNPKVDRLTLSCEMEINHLGDVVKHEIFQSVIKTTERMTYADVRSILEDEDEELMERYKPLVPMF
KEMAELAQILREKRMRRGAIDFDFKEAKVLVDEEGKPTDVVLRDRSISEKLIEEFMLVANETVAEHFHWMNVPFMYRIHE
EPKEDKLERFFEFVTNFGYAVKGRANEVHPRALQQILEMVQGQPEEPVISTVMLRSMKQARYDAESLGHFGLSTEFYTHF
TSPIRRYPDTIVHRLIREYIINGNIDNETQAKWHEKLPDIAEHSSNMERRAVEAERETDELKKAEYMLDKIGEEYDGMIS
SVTNFGLFVELPNTIEGLVHVSYLTDDYYRYDEQHFAMIGERTGNVFRIGDEITIRVINVNKDERAIDFEIVGMKGTPRR
KLKDRPIVIEQPKGGRKKRSGRGSDERGKDRKHERGSRGKGRADHSGKKGGKKKKPFFENVPGFKKKKKKRK

Sequences:

>Translated_792_residues
MEDIIQEHIDKLLLFMKEEAYKPLTIQELEAAFGIEDSAGFKDFVKALVMMEETGLVVRTRSNRYGLPEKMNLVRGKLIG
HARGFAFVVPEEKKTGDDDLFIPPTELNGALHGDTVLARISSQSSGSRQEGTIIRIVERGTKELVGTYTESKNFGFVIPD
NKRWTSDIFIPKSASMGAVEGHKVVVKITSYPQNRLSAEGEVIQILGHKNDPGVDILSVIHKHHLPLAFPEEVMEHANSV
PETISEEDLKDRRDLRDQMIVTIDGADAKDLDDAVTVTKLENGNYKLGVHIADVSHYVHEGSPIDVEAAERATSVYLVDR
VIPMIPHRLSNGICSLNPKVDRLTLSCEMEINHLGDVVKHEIFQSVIKTTERMTYADVRSILEDEDEELMERYKPLVPMF
KEMAELAQILREKRMRRGAIDFDFKEAKVLVDEEGKPTDVVLRDRSISEKLIEEFMLVANETVAEHFHWMNVPFMYRIHE
EPKEDKLERFFEFVTNFGYAVKGRANEVHPRALQQILEMVQGQPEEPVISTVMLRSMKQARYDAESLGHFGLSTEFYTHF
TSPIRRYPDTIVHRLIREYIINGNIDNETQAKWHEKLPDIAEHSSNMERRAVEAERETDELKKAEYMLDKIGEEYDGMIS
SVTNFGLFVELPNTIEGLVHVSYLTDDYYRYDEQHFAMIGERTGNVFRIGDEITIRVINVNKDERAIDFEIVGMKGTPRR
KLKDRPIVIEQPKGGRKKRSGRGSDERGKDRKHERGSRGKGRADHSGKKGGKKKKPFFENVPGFKKKKKKRK
>Mature_792_residues
MEDIIQEHIDKLLLFMKEEAYKPLTIQELEAAFGIEDSAGFKDFVKALVMMEETGLVVRTRSNRYGLPEKMNLVRGKLIG
HARGFAFVVPEEKKTGDDDLFIPPTELNGALHGDTVLARISSQSSGSRQEGTIIRIVERGTKELVGTYTESKNFGFVIPD
NKRWTSDIFIPKSASMGAVEGHKVVVKITSYPQNRLSAEGEVIQILGHKNDPGVDILSVIHKHHLPLAFPEEVMEHANSV
PETISEEDLKDRRDLRDQMIVTIDGADAKDLDDAVTVTKLENGNYKLGVHIADVSHYVHEGSPIDVEAAERATSVYLVDR
VIPMIPHRLSNGICSLNPKVDRLTLSCEMEINHLGDVVKHEIFQSVIKTTERMTYADVRSILEDEDEELMERYKPLVPMF
KEMAELAQILREKRMRRGAIDFDFKEAKVLVDEEGKPTDVVLRDRSISEKLIEEFMLVANETVAEHFHWMNVPFMYRIHE
EPKEDKLERFFEFVTNFGYAVKGRANEVHPRALQQILEMVQGQPEEPVISTVMLRSMKQARYDAESLGHFGLSTEFYTHF
TSPIRRYPDTIVHRLIREYIINGNIDNETQAKWHEKLPDIAEHSSNMERRAVEAERETDELKKAEYMLDKIGEEYDGMIS
SVTNFGLFVELPNTIEGLVHVSYLTDDYYRYDEQHFAMIGERTGNVFRIGDEITIRVINVNKDERAIDFEIVGMKGTPRR
KLKDRPIVIEQPKGGRKKRSGRGSDERGKDRKHERGSRGKGRADHSGKKGGKKKKPFFENVPGFKKKKKKRK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=515, Percent_Identity=30.873786407767, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI190014623, Length=515, Percent_Identity=30.873786407767, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI134288890, Length=416, Percent_Identity=33.1730769230769, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI19115966, Length=595, Percent_Identity=27.8991596638655, Blast_Score=195, Evalue=2e-49,
Organism=Homo sapiens, GI219521928, Length=595, Percent_Identity=27.8991596638655, Blast_Score=194, Evalue=2e-49,
Organism=Escherichia coli, GI87082383, Length=706, Percent_Identity=39.3767705382436, Blast_Score=521, Evalue=1e-148,
Organism=Escherichia coli, GI1787542, Length=641, Percent_Identity=25.2730109204368, Blast_Score=148, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17553506, Length=541, Percent_Identity=29.9445471349353, Blast_Score=207, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI212645896, Length=492, Percent_Identity=28.8617886178862, Blast_Score=189, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6324552, Length=594, Percent_Identity=28.7878787878788, Blast_Score=208, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6320499, Length=422, Percent_Identity=24.6445497630332, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323943, Length=432, Percent_Identity=23.3796296296296, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24649634, Length=479, Percent_Identity=31.1064718162839, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24654592, Length=363, Percent_Identity=32.7823691460055, Blast_Score=186, Evalue=6e-47,
Organism=Drosophila melanogaster, GI19922976, Length=363, Percent_Identity=32.7823691460055, Blast_Score=186, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24654597, Length=363, Percent_Identity=32.7823691460055, Blast_Score=186, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 90588; Mature: 90588

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDIIQEHIDKLLLFMKEEAYKPLTIQELEAAFGIEDSAGFKDFVKALVMMEETGLVVRT
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEE
RSNRYGLPEKMNLVRGKLIGHARGFAFVVPEEKKTGDDDLFIPPTELNGALHGDTVLARI
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCHHCCCCCCCCHHEEEE
SSQSSGSRQEGTIIRIVERGTKELVGTYTESKNFGFVIPDNKRWTSDIFIPKSASMGAVE
CCCCCCCCCCCCEEEEEHHCHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCCCCC
GHKVVVKITSYPQNRLSAEGEVIQILGHKNDPGVDILSVIHKHHLPLAFPEEVMEHANSV
CCEEEEEEECCCCHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCC
PETISEEDLKDRRDLRDQMIVTIDGADAKDLDDAVTVTKLENGNYKLGVHIADVSHYVHE
CHHCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHC
GSPIDVEAAERATSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMEINHLGDVVKH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEEEEEHHHHHHHHHH
EIFQSVIKTTERMTYADVRSILEDEDEELMERYKPLVPMFKEMAELAQILREKRMRRGAI
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
DFDFKEAKVLVDEEGKPTDVVLRDRSISEKLIEEFMLVANETVAEHFHWMNVPFMYRIHE
CCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
EPKEDKLERFFEFVTNFGYAVKGRANEVHPRALQQILEMVQGQPEEPVISTVMLRSMKQA
CCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RYDAESLGHFGLSTEFYTHFTSPIRRYPDTIVHRLIREYIINGNIDNETQAKWHEKLPDI
HCCHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCH
AEHSSNMERRAVEAERETDELKKAEYMLDKIGEEYDGMISSVTNFGLFVELPNTIEGLVH
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEECCHHHHHHEE
VSYLTDDYYRYDEQHFAMIGERTGNVFRIGDEITIRVINVNKDERAIDFEIVGMKGTPRR
EHHHHHHHHHHCCHHHHHHHCCCCCEEEECCEEEEEEEECCCCCCEEEEEEEECCCCCCH
KLKDRPIVIEQPKGGRKKRSGRGSDERGKDRKHERGSRGKGRADHSGKKGGKKKKPFFEN
HCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHC
VPGFKKKKKKRK
CCCHHHHHHCCC
>Mature Secondary Structure
MEDIIQEHIDKLLLFMKEEAYKPLTIQELEAAFGIEDSAGFKDFVKALVMMEETGLVVRT
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEE
RSNRYGLPEKMNLVRGKLIGHARGFAFVVPEEKKTGDDDLFIPPTELNGALHGDTVLARI
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCHHCCCCCCCCHHEEEE
SSQSSGSRQEGTIIRIVERGTKELVGTYTESKNFGFVIPDNKRWTSDIFIPKSASMGAVE
CCCCCCCCCCCCEEEEEHHCHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCCCCC
GHKVVVKITSYPQNRLSAEGEVIQILGHKNDPGVDILSVIHKHHLPLAFPEEVMEHANSV
CCEEEEEEECCCCHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCC
PETISEEDLKDRRDLRDQMIVTIDGADAKDLDDAVTVTKLENGNYKLGVHIADVSHYVHE
CHHCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHC
GSPIDVEAAERATSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMEINHLGDVVKH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEEEEEHHHHHHHHHH
EIFQSVIKTTERMTYADVRSILEDEDEELMERYKPLVPMFKEMAELAQILREKRMRRGAI
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
DFDFKEAKVLVDEEGKPTDVVLRDRSISEKLIEEFMLVANETVAEHFHWMNVPFMYRIHE
CCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
EPKEDKLERFFEFVTNFGYAVKGRANEVHPRALQQILEMVQGQPEEPVISTVMLRSMKQA
CCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RYDAESLGHFGLSTEFYTHFTSPIRRYPDTIVHRLIREYIINGNIDNETQAKWHEKLPDI
HCCHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCH
AEHSSNMERRAVEAERETDELKKAEYMLDKIGEEYDGMISSVTNFGLFVELPNTIEGLVH
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEECCHHHHHHEE
VSYLTDDYYRYDEQHFAMIGERTGNVFRIGDEITIRVINVNKDERAIDFEIVGMKGTPRR
EHHHHHHHHHHCCHHHHHHHCCCCCEEEECCEEEEEEEECCCCCCEEEEEEEECCCCCCH
KLKDRPIVIEQPKGGRKKRSGRGSDERGKDRKHERGSRGKGRADHSGKKGGKKKKPFFEN
HCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHC
VPGFKKKKKKRK
CCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]