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The map label for this gene is ycbM [H]

Identifier: 152976929

GI number: 152976929

Start: 3298591

End: 3299526

Strand: Reverse

Name: ycbM [H]

Synonym: Bcer98_3232

Alternate gene names: 152976929

Gene position: 3299526-3298591 (Counterclockwise)

Preceding gene: 152976930

Following gene: 152976928

Centisome position: 80.73

GC content: 30.98

Gene sequence:

>936_bases
ATGTTTTCTCTGCTCATGATTGTTATTTTTATATTATTAGGTGTCATTTATTTTCAATATAGAATAGGGAAAAGCAAGAG
TGCGAATATACGTTATACGTATGAAAAATTAGAGAATATTATAAAACAACAAACCGGTGAGAAATTATTAGTTGTAACGG
ATGATAAAGAACTACAACAATTATTAGTAGCAATTAATCATTTATTAGATGCGAAACAAAAAACGAATGCGAATCATGCG
AAGGTTGAAATTTCGATGAGAAAGATGCTTTCTAACATTTCTCATGATTTGAAAACGCCGCTCACTGTTATTCTTGGATA
TACGGAAATGTTAAATAAAGATAAAACGATGAATAAAGAAGAACAACACATACTGTTAGAAAAGGTACATGTAAAAACGT
TAGAAGTAATGGAACTTATTCATAAATTCTTTGATTTGGCGAGATTAGAATCTGGAGATAAAGCAATTGAAATAACAAAG
GTGAATATGAATGAAGTGTGCCGAGAAAAAATTTTAACGTTTTATGATTTGATAACGACTAAAGGGTTTGAGGTACATAT
TGATATACCAGAGAAAAATATGTATGCATTTGGGAATACAGAAGTATTAGGTCGTGTGTTAAATAATTTAATATCCAATG
CCCTTACGTATGGATATGATGGAAAAATACTTGGTATTACGTTAAGCGATGATGAACGATATGTATATGTTGATGTATGG
GATCGCGGTAAAGGAATTAATGAATCACATATTGATAAAGTATTTGAGCGTATGTATACGTTAGAGGATTCAAGGAATCG
ACTATATCAAGGTAGTGGTCTTGGACTCACAATTACAAAACGACTGGTAGAAGCTTTAGGGGGAGAAATTCATCTTTTTA
GTAAGCCATATGAAAAAACAGTATTTACGATTATGCTGAGAAAAATCGATTTTTAG

Upstream 100 bases:

>100_bases
CATATGAGAAGATTACGTGAGAAAATTGAAACAGATCCATCCAATCCAGAATATATTAAAACATTATGGGGAATTGGCTA
TAAGTTGGAAGTGATGTAGC

Downstream 100 bases:

>100_bases
CTTGTAGAAATAGGATTCTACAAGCTTTTTTAAGCGTAAGGAATTTGTAAGGAAGGGGTAAGAAAAAAGAGACCTTCATT
GTCTATGCTAGAGATATAAA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MFSLLMIVIFILLGVIYFQYRIGKSKSANIRYTYEKLENIIKQQTGEKLLVVTDDKELQQLLVAINHLLDAKQKTNANHA
KVEISMRKMLSNISHDLKTPLTVILGYTEMLNKDKTMNKEEQHILLEKVHVKTLEVMELIHKFFDLARLESGDKAIEITK
VNMNEVCREKILTFYDLITTKGFEVHIDIPEKNMYAFGNTEVLGRVLNNLISNALTYGYDGKILGITLSDDERYVYVDVW
DRGKGINESHIDKVFERMYTLEDSRNRLYQGSGLGLTITKRLVEALGGEIHLFSKPYEKTVFTIMLRKIDF

Sequences:

>Translated_311_residues
MFSLLMIVIFILLGVIYFQYRIGKSKSANIRYTYEKLENIIKQQTGEKLLVVTDDKELQQLLVAINHLLDAKQKTNANHA
KVEISMRKMLSNISHDLKTPLTVILGYTEMLNKDKTMNKEEQHILLEKVHVKTLEVMELIHKFFDLARLESGDKAIEITK
VNMNEVCREKILTFYDLITTKGFEVHIDIPEKNMYAFGNTEVLGRVLNNLISNALTYGYDGKILGITLSDDERYVYVDVW
DRGKGINESHIDKVFERMYTLEDSRNRLYQGSGLGLTITKRLVEALGGEIHLFSKPYEKTVFTIMLRKIDF
>Mature_311_residues
MFSLLMIVIFILLGVIYFQYRIGKSKSANIRYTYEKLENIIKQQTGEKLLVVTDDKELQQLLVAINHLLDAKQKTNANHA
KVEISMRKMLSNISHDLKTPLTVILGYTEMLNKDKTMNKEEQHILLEKVHVKTLEVMELIHKFFDLARLESGDKAIEITK
VNMNEVCREKILTFYDLITTKGFEVHIDIPEKNMYAFGNTEVLGRVLNNLISNALTYGYDGKILGITLSDDERYVYVDVW
DRGKGINESHIDKVFERMYTLEDSRNRLYQGSGLGLTITKRLVEALGGEIHLFSKPYEKTVFTIMLRKIDF

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=27.2373540856031, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786912, Length=289, Percent_Identity=24.5674740484429, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789149, Length=286, Percent_Identity=24.8251748251748, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786783, Length=306, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=26.7441860465116, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788713, Length=232, Percent_Identity=25.4310344827586, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786600, Length=206, Percent_Identity=28.1553398058252, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI145693157, Length=254, Percent_Identity=25.5905511811024, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=26.8722466960352, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=220, Percent_Identity=25, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=212, Percent_Identity=24.5283018867925, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=25.1012145748988, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=200, Percent_Identity=24.5, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=25.9574468085106, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789403, Length=248, Percent_Identity=22.9838709677419, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788279, Length=228, Percent_Identity=25.8771929824561, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790551, Length=243, Percent_Identity=27.9835390946502, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35994; Mature: 35994

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSLLMIVIFILLGVIYFQYRIGKSKSANIRYTYEKLENIIKQQTGEKLLVVTDDKELQQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCHHHHH
LLVAINHLLDAKQKTNANHAKVEISMRKMLSNISHDLKTPLTVILGYTEMLNKDKTMNKE
HHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCH
EQHILLEKVHVKTLEVMELIHKFFDLARLESGDKAIEITKVNMNEVCREKILTFYDLITT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHC
KGFEVHIDIPEKNMYAFGNTEVLGRVLNNLISNALTYGYDGKILGITLSDDERYVYVDVW
CCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEE
DRGKGINESHIDKVFERMYTLEDSRNRLYQGSGLGLTITKRLVEALGGEIHLFSKPYEKT
CCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHH
VFTIMLRKIDF
HHHHHHHHHCC
>Mature Secondary Structure
MFSLLMIVIFILLGVIYFQYRIGKSKSANIRYTYEKLENIIKQQTGEKLLVVTDDKELQQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCHHHHH
LLVAINHLLDAKQKTNANHAKVEISMRKMLSNISHDLKTPLTVILGYTEMLNKDKTMNKE
HHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCH
EQHILLEKVHVKTLEVMELIHKFFDLARLESGDKAIEITKVNMNEVCREKILTFYDLITT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHC
KGFEVHIDIPEKNMYAFGNTEVLGRVLNNLISNALTYGYDGKILGITLSDDERYVYVDVW
CCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEE
DRGKGINESHIDKVFERMYTLEDSRNRLYQGSGLGLTITKRLVEALGGEIHLFSKPYEKT
CCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHH
VFTIMLRKIDF
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]