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The map label for this gene is ycbL [H]

Identifier: 152976930

GI number: 152976930

Start: 3299528

End: 3300220

Strand: Reverse

Name: ycbL [H]

Synonym: Bcer98_3233

Alternate gene names: 152976930

Gene position: 3300220-3299528 (Counterclockwise)

Preceding gene: 152976933

Following gene: 152976929

Centisome position: 80.75

GC content: 33.19

Gene sequence:

>693_bases
ATGTCACGTCATATTTTATTAATAGAAGATGACATTTCGATTCAAGAAATGGTCGAGAAATATTTATCAAAAGAAGGATT
TCAAGTTACATTTGCTTCTGATGGAGAAGAAGGCGTTGCGAAATTTTTTCATGGATCATTTGACTTGATTATTCTTGATA
TTATGATGCCAAAGCTAGATGGTTTAGAAGTTGTGAGAATTATTCGCGAAAAAAGCGCTGTACCGATTTTAATGATGTCC
GCAAAAGATACAGATATCGATAAGGCGGTGGGGCTAGGACTTGGTGCAGATGATTACATTTGCAAACCATTCTCTATGAT
TGAATTGGCAGCGAGAGCAAAGGCAAGTATTCGAAGATTTACAAAGTATTCAGCTACGGAGCAAAAAGAAGAAATGATTG
AGATTGGTGATTTGAAAATAGATCCGATTAACTTCACTGTGTATAAAAAAGAAAAACAGTTAAAACTTACTTTAAAAGAA
TTCGAAATTTTGAAATTGTTCGCAAGGAATCAAAATCGTGTATTTACAAAAGCGCAAATATATAATCTCATTTGGAATGA
AGAATACTATGGCGATGATAATGTTATTAACGTTCATATGAGAAGATTACGTGAGAAAATTGAAACAGATCCATCCAATC
CAGAATATATTAAAACATTATGGGGAATTGGCTATAAGTTGGAAGTGATGTAG

Upstream 100 bases:

>100_bases
AAGGAAAGGAAGTTGGTTTGCACATTCATATAATTCTTTCCACTTTATAACAGTTACGATACAATGAAATTGTTAATATT
TGTAAAAAGGGGATAGGAGC

Downstream 100 bases:

>100_bases
CATGTTTTCTCTGCTCATGATTGTTATTTTTATATTATTAGGTGTCATTTATTTTCAATATAGAATAGGGAAAAGCAAGA
GTGCGAATATACGTTATACG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSRHILLIEDDISIQEMVEKYLSKEGFQVTFASDGEEGVAKFFHGSFDLIILDIMMPKLDGLEVVRIIREKSAVPILMMS
AKDTDIDKAVGLGLGADDYICKPFSMIELAARAKASIRRFTKYSATEQKEEMIEIGDLKIDPINFTVYKKEKQLKLTLKE
FEILKLFARNQNRVFTKAQIYNLIWNEEYYGDDNVINVHMRRLREKIETDPSNPEYIKTLWGIGYKLEVM

Sequences:

>Translated_230_residues
MSRHILLIEDDISIQEMVEKYLSKEGFQVTFASDGEEGVAKFFHGSFDLIILDIMMPKLDGLEVVRIIREKSAVPILMMS
AKDTDIDKAVGLGLGADDYICKPFSMIELAARAKASIRRFTKYSATEQKEEMIEIGDLKIDPINFTVYKKEKQLKLTLKE
FEILKLFARNQNRVFTKAQIYNLIWNEEYYGDDNVINVHMRRLREKIETDPSNPEYIKTLWGIGYKLEVM
>Mature_229_residues
SRHILLIEDDISIQEMVEKYLSKEGFQVTFASDGEEGVAKFFHGSFDLIILDIMMPKLDGLEVVRIIREKSAVPILMMSA
KDTDIDKAVGLGLGADDYICKPFSMIELAARAKASIRRFTKYSATEQKEEMIEIGDLKIDPINFTVYKKEKQLKLTLKEF
EILKLFARNQNRVFTKAQIYNLIWNEEYYGDDNVINVHMRRLREKIETDPSNPEYIKTLWGIGYKLEVM

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=36.6071428571429, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=37.6106194690265, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=35.6521739130435, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=35.5855855855856, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=33.1838565022422, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=37.1681415929204, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=34.070796460177, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=29.6943231441048, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=32.4444444444444, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=29.9107142857143, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=29.004329004329, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=30.8035714285714, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=29.3859649122807, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=28.7610619469027, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=29.9065420560748, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=104, Percent_Identity=30.7692307692308, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=109, Percent_Identity=32.1100917431193, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=110, Percent_Identity=35.4545454545455, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26660; Mature: 26529

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRHILLIEDDISIQEMVEKYLSKEGFQVTFASDGEEGVAKFFHGSFDLIILDIMMPKLD
CCCEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCHHEEEEEEHHCCCC
GLEVVRIIREKSAVPILMMSAKDTDIDKAVGLGLGADDYICKPFSMIELAARAKASIRRF
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TKYSATEQKEEMIEIGDLKIDPINFTVYKKEKQLKLTLKEFEILKLFARNQNRVFTKAQI
HHHCCHHHHHHHHHHCCEEECCEEEEEEECCCCEEEHHHHHHHHHHHHCCCCCEEHHHHH
YNLIWNEEYYGDDNVINVHMRRLREKIETDPSNPEYIKTLWGIGYKLEVM
HHHHCCCCEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEC
>Mature Secondary Structure 
SRHILLIEDDISIQEMVEKYLSKEGFQVTFASDGEEGVAKFFHGSFDLIILDIMMPKLD
CCEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCHHEEEEEEHHCCCC
GLEVVRIIREKSAVPILMMSAKDTDIDKAVGLGLGADDYICKPFSMIELAARAKASIRRF
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TKYSATEQKEEMIEIGDLKIDPINFTVYKKEKQLKLTLKEFEILKLFARNQNRVFTKAQI
HHHCCHHHHHHHHHHCCEEECCEEEEEEECCCCEEEHHHHHHHHHHHHCCCCCEEHHHHH
YNLIWNEEYYGDDNVINVHMRRLREKIETDPSNPEYIKTLWGIGYKLEVM
HHHHCCCCEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]