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The map label for this gene is appB [H]

Identifier: 152974064

GI number: 152974064

Start: 232123

End: 233079

Strand: Direct

Name: appB [H]

Synonym: Bcer98_0220

Alternate gene names: 152974064

Gene position: 232123-233079 (Clockwise)

Preceding gene: 152974063

Following gene: 152974065

Centisome position: 5.68

GC content: 35.32

Gene sequence:

>957_bases
GTGAAAACATATATCATTCGTAGGTTGTTACAAATGATCCCTACACTGTTTGGTACATCTATTATTATCTTCTTCTTATT
CGCACTTTTACCAGGGGATTATATTGATTCGAATCCGAAGATTACGCCAGAAAGAGCTGCGGAGCTGAGGGAACTATATG
GGTTAAACAAACCAATTATGGAACGTTACTTTCATTGGTTGGGTAATGCATTACAAGGGAACTTTGGTTTTTCTTTGCAA
TATCAAGAATCTGTAACATCGCTATTAAATAAATTTATTTGGAATTCGTTTATGGTAGCGATTGTAGCTTTATTTTTAAT
TTGGTTAATCGCGCTTATTGTCGGAGTATTTTCAGCCACAAAACAGCACTCCTTATTCGATAAGCTTGTGACAGTCGGAG
TTTTTGCTGCAATGTCATTTCCGTCATTCTTTATTGGCTTATTTCTGATTAAAGTCTTTGCTGTAGATTTTCATTTGTTA
CCGATAGGTGGAATGATTGATGTTGGTAGTAATTCAACCGGTTTTGCTTATGTTTTAGAAGTTGCTGGACATATGATCCT
ACCAGTATTTATTTTGACACTTCTTGGTGTAGGGTCGTTAACTCGTTATTTTAGAACAAGTATGCTTGAGGTTGTAAGAC
AAGATTATATTCGCACAGCACGAGCAAAAGGGCTCAAGGAGAAGGCTGTTATTTATAAACATGCACTAAAAAATGCCATT
TTACCAGCTATTACATTGCTTGCATTTGAACTACCAGGATTATTCTCTGGTGCAATTATTATTGAACAAATTTTTAACTG
GCCTGGAATTGGAAGCATTCAATTAGAGGCATTAAATTTTCGAGATTATACAGTATTAATGGGCTTTACAATGTTTCTTT
CTGTTTTAACGATTGTTTCAAATTTCTTAGCGGATATTGTATATGCTGTTGTGGATCCACGCATTCGGTTGCAGTAA

Upstream 100 bases:

>100_bases
TAAAGATAAGTCCGTATAAATAGAAGACATTTTTTTATTCGAAACGCTGAATGAAAAAATGTTCTTCTATTTTAAGTACA
TAAGATTGGGGAGACGAAGG

Downstream 100 bases:

>100_bases
AGGGGGGAGAGAGATGGAAGTTGTTACAACAACTACAGAGATAAAGAAGAAAAAGAAAAGAAGAAATGAATCGTCGCCAT
GGCGACAGGCCCATAGGAAA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKTYIIRRLLQMIPTLFGTSIIIFFLFALLPGDYIDSNPKITPERAAELRELYGLNKPIMERYFHWLGNALQGNFGFSLQ
YQESVTSLLNKFIWNSFMVAIVALFLIWLIALIVGVFSATKQHSLFDKLVTVGVFAAMSFPSFFIGLFLIKVFAVDFHLL
PIGGMIDVGSNSTGFAYVLEVAGHMILPVFILTLLGVGSLTRYFRTSMLEVVRQDYIRTARAKGLKEKAVIYKHALKNAI
LPAITLLAFELPGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMGFTMFLSVLTIVSNFLADIVYAVVDPRIRLQ

Sequences:

>Translated_318_residues
MKTYIIRRLLQMIPTLFGTSIIIFFLFALLPGDYIDSNPKITPERAAELRELYGLNKPIMERYFHWLGNALQGNFGFSLQ
YQESVTSLLNKFIWNSFMVAIVALFLIWLIALIVGVFSATKQHSLFDKLVTVGVFAAMSFPSFFIGLFLIKVFAVDFHLL
PIGGMIDVGSNSTGFAYVLEVAGHMILPVFILTLLGVGSLTRYFRTSMLEVVRQDYIRTARAKGLKEKAVIYKHALKNAI
LPAITLLAFELPGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMGFTMFLSVLTIVSNFLADIVYAVVDPRIRLQ
>Mature_318_residues
MKTYIIRRLLQMIPTLFGTSIIIFFLFALLPGDYIDSNPKITPERAAELRELYGLNKPIMERYFHWLGNALQGNFGFSLQ
YQESVTSLLNKFIWNSFMVAIVALFLIWLIALIVGVFSATKQHSLFDKLVTVGVFAAMSFPSFFIGLFLIKVFAVDFHLL
PIGGMIDVGSNSTGFAYVLEVAGHMILPVFILTLLGVGSLTRYFRTSMLEVVRQDYIRTARAKGLKEKAVIYKHALKNAI
LPAITLLAFELPGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMGFTMFLSVLTIVSNFLADIVYAVVDPRIRLQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=34.2261904761905, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1787053, Length=320, Percent_Identity=31.5625, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1787497, Length=317, Percent_Identity=35.9621451104101, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1789888, Length=321, Percent_Identity=34.2679127725857, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1788504, Length=362, Percent_Identity=30.1104972375691, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=30.3680981595092, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=25.3731343283582, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35774; Mature: 35774

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYIIRRLLQMIPTLFGTSIIIFFLFALLPGDYIDSNPKITPERAAELRELYGLNKPIM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHH
ERYFHWLGNALQGNFGFSLQYQESVTSLLNKFIWNSFMVAIVALFLIWLIALIVGVFSAT
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQHSLFDKLVTVGVFAAMSFPSFFIGLFLIKVFAVDFHLLPIGGMIDVGSNSTGFAYVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
VAGHMILPVFILTLLGVGSLTRYFRTSMLEVVRQDYIRTARAKGLKEKAVIYKHALKNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LPAITLLAFELPGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMGFTMFLSVLTIVS
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
NFLADIVYAVVDPRIRLQ
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTYIIRRLLQMIPTLFGTSIIIFFLFALLPGDYIDSNPKITPERAAELRELYGLNKPIM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHH
ERYFHWLGNALQGNFGFSLQYQESVTSLLNKFIWNSFMVAIVALFLIWLIALIVGVFSAT
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQHSLFDKLVTVGVFAAMSFPSFFIGLFLIKVFAVDFHLLPIGGMIDVGSNSTGFAYVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
VAGHMILPVFILTLLGVGSLTRYFRTSMLEVVRQDYIRTARAKGLKEKAVIYKHALKNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LPAITLLAFELPGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMGFTMFLSVLTIVS
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
NFLADIVYAVVDPRIRLQ
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]