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The map label for this gene is appC [H]

Identifier: 152974065

GI number: 152974065

Start: 233093

End: 234016

Strand: Direct

Name: appC [H]

Synonym: Bcer98_0221

Alternate gene names: 152974065

Gene position: 233093-234016 (Clockwise)

Preceding gene: 152974064

Following gene: 152974066

Centisome position: 5.7

GC content: 37.88

Gene sequence:

>924_bases
ATGGAAGTTGTTACAACAACTACAGAGATAAAGAAGAAAAAGAAAAGAAGAAATGAATCGTCGCCATGGCGACAGGCCCA
TAGGAAAATTAAGAAAAATAAAATGGCGTTAGTCGGGTTTTATGCATTAATTTTTATGTTTTTATTTTGTTTTATTGGAC
CATTCTTTTCACCATATGCATCTGGAAAAATACAAGTTACTTTAATAAATAAACCACCTAGCTTGTTACATTGGCTTGGT
ACAGATCAACTTGGAAGAGATGTATTAACAAGGCTTATGCAAGCGGGGCGTATATCACTAACAATTGGCTTGGCATCAAT
GGTTCTATCGGTAATTTTAGGTGCTTTATTAGGTGCCATTTCTGGTTTTTATCGAGGTATTGTTGACAACGTTATTATGC
GCCTTGCCGATATTTTAATGTCAATGCCAGGATTACCTTTACTCATTATAATGGGAGCGATTTTATCAGAGTGGAAAATC
CCATCAAACTACCGTCTTTATGTCATTATGATTATTTTAAGTTTGGTGGGTTGGCCAGGACTCGCTCGTCTTGTTAGAGG
ACAAATTTTGTCGCTTCGGGAACAATCCTTTATGCAAGCAGCTGATGTGTTAGGGTTGAAAGACTATCGTAAGATTGTGT
ATCACTTAATTCCGAACGTATTACCGTTATTGATAGTTGTATCTACCTTAGGGGTTGCAGGGTCTATTTTAGGGGAGTCA
GCACTCAGTTATCTAGGTCTTGGAGTTGTTCCACCTACACCTTCATGGGGGAATATGATTCATGCAGCAAACTCACTAAT
TGATTTTCAAAAGCGTCCGTGGTTATGGATTCCACCAGGGTTTGCTATTTTTATAACCGTTATATCAATTAACTTACTTG
GTGATGCACTTCGTGATGCATTAGATCCAAAGATGAAGCGGTAG

Upstream 100 bases:

>100_bases
ATGTTTCTTTCTGTTTTAACGATTGTTTCAAATTTCTTAGCGGATATTGTATATGCTGTTGTGGATCCACGCATTCGGTT
GCAGTAAAGGGGGGAGAGAG

Downstream 100 bases:

>100_bases
GTGAAAAGAATGAGCAGAGCAATAGTAGAATTAAAAGATTTACAAACACACTTTCAAACAGAAGAGGGGATTGTGAAAGC
TGTTAATCATGTGAGCTTTT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MEVVTTTTEIKKKKKRRNESSPWRQAHRKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVTLINKPPSLLHWLG
TDQLGRDVLTRLMQAGRISLTIGLASMVLSVILGALLGAISGFYRGIVDNVIMRLADILMSMPGLPLLIIMGAILSEWKI
PSNYRLYVIMIILSLVGWPGLARLVRGQILSLREQSFMQAADVLGLKDYRKIVYHLIPNVLPLLIVVSTLGVAGSILGES
ALSYLGLGVVPPTPSWGNMIHAANSLIDFQKRPWLWIPPGFAIFITVISINLLGDALRDALDPKMKR

Sequences:

>Translated_307_residues
MEVVTTTTEIKKKKKRRNESSPWRQAHRKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVTLINKPPSLLHWLG
TDQLGRDVLTRLMQAGRISLTIGLASMVLSVILGALLGAISGFYRGIVDNVIMRLADILMSMPGLPLLIIMGAILSEWKI
PSNYRLYVIMIILSLVGWPGLARLVRGQILSLREQSFMQAADVLGLKDYRKIVYHLIPNVLPLLIVVSTLGVAGSILGES
ALSYLGLGVVPPTPSWGNMIHAANSLIDFQKRPWLWIPPGFAIFITVISINLLGDALRDALDPKMKR
>Mature_307_residues
MEVVTTTTEIKKKKKRRNESSPWRQAHRKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVTLINKPPSLLHWLG
TDQLGRDVLTRLMQAGRISLTIGLASMVLSVILGALLGAISGFYRGIVDNVIMRLADILMSMPGLPLLIIMGAILSEWKI
PSNYRLYVIMIILSLVGWPGLARLVRGQILSLREQSFMQAADVLGLKDYRKIVYHLIPNVLPLLIVVSTLGVAGSILGES
ALSYLGLGVVPPTPSWGNMIHAANSLIDFQKRPWLWIPPGFAIFITVISINLLGDALRDALDPKMKR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=287, Percent_Identity=35.5400696864112, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1787760, Length=307, Percent_Identity=32.2475570032573, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787498, Length=303, Percent_Identity=35.6435643564356, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789964, Length=295, Percent_Identity=36.9491525423729, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1789889, Length=248, Percent_Identity=39.1129032258064, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788505, Length=235, Percent_Identity=32.7659574468085, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787549, Length=285, Percent_Identity=30.1754385964912, Blast_Score=114, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34095; Mature: 34095

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVVTTTTEIKKKKKRRNESSPWRQAHRKIKKNKMALVGFYALIFMFLFCFIGPFFSPYA
CCEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SGKIQVTLINKPPSLLHWLGTDQLGRDVLTRLMQAGRISLTIGLASMVLSVILGALLGAI
CCEEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
SGFYRGIVDNVIMRLADILMSMPGLPLLIIMGAILSEWKIPSNYRLYVIMIILSLVGWPG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHH
LARLVRGQILSLREQSFMQAADVLGLKDYRKIVYHLIPNVLPLLIVVSTLGVAGSILGES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSYLGLGVVPPTPSWGNMIHAANSLIDFQKRPWLWIPPGFAIFITVISINLLGDALRDA
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
LDPKMKR
CCCCCCC
>Mature Secondary Structure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CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]